Questions and Answers
Which of the following is NOT an advantage of monoclonal antibodies?
Low cost
What is the primary method of absorption of monoclonal antibodies?
Intravenous injection
How are monoclonal antibodies eliminated from the body?
Receptor-mediated endocytosis
Which factor can lead to faster drug clearance and lower levels of monoclonal antibodies in the body?
Signup and view all the answers
Why are monoclonal antibodies considered as foreign proteins in the body?
Signup and view all the answers
Which of the following is a disadvantage of monoclonal antibodies?
Signup and view all the answers
Which of the following statements about TNF inhibitors is TRUE?
Signup and view all the answers
What is a common feature of anti-TNF biologics like Infliximab, Golimumab, and Adalimumab?
Signup and view all the answers
Which of the following is a potential adverse effect associated with anti-cytokine biologics like Infliximab?
Signup and view all the answers
Which type of biologic targets B lymphocytes directly?
Signup and view all the answers
What distinguishes anti-integrin biologics from other biologics mentioned in the text?
Signup and view all the answers
Why must TNF inhibitors like Infliximab be dosed less frequently than small molecule drugs?
Signup and view all the answers
Which adverse effect is associated with TNFα inhibitors?
Signup and view all the answers
Which statement about anti-TNF biologics is false?
Signup and view all the answers
Which biologic targets the p40 subunit to inhibit IL-12/23?
Signup and view all the answers
Which disease is NOT commonly treated with anti-B lymphocyte biologics?
Signup and view all the answers
Which chronic inflammatory disease is effectively treated with anti-integrin biologics?
Signup and view all the answers
What is a common class effect associated with TNFα inhibitors?
Signup and view all the answers