70 Questions
Muscle Tissue is generated by interaction of
Actin and Myosin
contractile role in addition to being able to secrete collagen
Myofibroblasts
what are the 3 single cell contractile units
Myoepithelial cells Pericytes Myofibroblasts
cytoplasm of muscle cells
Sarcoplasm
3 Multicellular contractile units
Skeletal Muscle Cardiac Muscle Smooth Muscle
component of a certain secretory glands
Myoepithelial cells
smooth muscle like cells
Pericytes
surrounding cell membrane or plasmalemma
sarcolemma
fusiform, lack striation, slow and involuntary contractions
Smooth Muscle
long, multinucleated, with cross striations, quick, forceful, voluntary
Skeletal Muscle
smooth endoplasmic reticulum
sarcoplasmic reticulum
surrounds all 3 types of muscles; contractile forces from internal contractile proteins to external lamina via link protein.
External Lamina
intercalated discs, involuntary, vigorous, and rhythmic
Cardiac Muscle
elongated muscle cells
Muscle Fibers Myocytes
process of sliding interaction of myosin filaments along actin filaments
Sliding Filament Mechanism
Functions of Muscular Tissue
Producing Body Movements Stabilizing body positions Storing and Moving Substances Generating Heat
consists of elongated muscle cells called muscle fibers or myocytes
Muscle Tissue
Usually attached to bones by tendons
Skeletal Muscle Tissue
long cylindrical fiber
Skeletal Muscle Tissue
Structures of Skeletal Muscle Fiber
Sarcolemma Nuclei Sarcoplasm
long finger like invaginations of the sarcolemma that penetrate into thesarcoplasm
Transverse tubules
found just beneath the sarcolemma
Nuclei
how many nuclei are found in each skeletal muscle fiber
100 or more
red colored protein found only in muscle; binds oxygen molecules that diffuse into muscle fibers
Myoglobin
large molecule composed of many glucose molecules; can be used for ATP Synthesis
Glycogen
lie in rows throughout the muscle fiber
Mitochondria
contractile organelles of skeletal muscle; arranged in parallel bundles
Myofibrils
fluid filled system of membranous sacs that encircles each myofibril
Sarcoplasmic reticulum
basic functional contractile unit of myofibril
Sarcomere
narrow region in center of each A band
H Zone
narrow, plate shaped regions of dense materials
Z discs
region in center of H zone that contains proteins that hold filaments together at center of sarcomere
M line
consists of long series of sarcomeres
Structure of Myofibril
dark, middle part of sarcomere
A band
lighter, less dense area of sarcomere
I band
3 layers of Skeletal Muscle
Epimysium Perimysium Endomysium
surrounds and separates individual muscle fibers from one another; consists mostly of reticular fibers
Endomysium
outer layer, encircling the entire muscle; consists of dense irregular connective tissue
Epimysium
surrounds groups of 10 to 100 or more muscle fibers, separating the bundles called fasicles; consists of dense irregular collagenous connective tissue
Perimysium
3 kinds of muscle proteins
Contractile Regulatory Structural
help switch the contraction process on and off
Regulatory Proteins
generate force during contraction
Contractile Proteins
main component of thin filament; functions as a motor protein
Actin
component of thin filament
Tropomyosin
makes up thick filament; a molecule consists of a tail and two heads
Myosin
keep thick and thin filaments of myofibrils in proper alignment
Structural Proteins
connects Z disc to M line of sarcomere
Titin
regulatory protein that is a component of thin filament
Troponin
forms M line of sarcomere; binds to titin molecules and connects adjacent filaments to one another
Myomesin
links thin filaments of sarcomere to integral membrane proteins
Dystrophin
wraps around entire length of each thin filament; helps anchor thin filaments and regulates length of thin filaments during development
Nebulin
structural proteins of Z discs that attaches to actin molecules of thin filament
a-Actinin
3 types of skeletal muscle fibers
Slow Oxidative Fast Glycolytic Fast-Oxidative Glycolytic
largest and contain large amounts of myoglobin
Fast- Oxidative Glycolytic
fibers appear dark red because they contain large amounts of myglobin
Slow Oxidative
have low myoglobin content; contain large amounts of glycogen and generate ATP
Fast Glycolytic
located in the heart and large vessels attached to the heart
Cardiac Muscle Tissue
Branched cylindrical fiber with one centrally located nucleus
Cardiac Muscle Tissue
regulatory proteins
tropomyosin and troponin
length of cardiac muscle tissue (long)
50-100um
diameter of cardiac muscle tissue (large)
10-20um
found in walls of hollow viscera, airways, blood vessels etc…
Smooth Muscle Tissue
shape of fibers
fusiform
develop from mesodermal cells
Smooth Muscle Tissue
length of smooth muscle fiber (Intermediate)
30-200um
Diameter of smooth muscular fiber (small)
3-8um
it can occur in skeletal muscle because of a population of reserve muscle satellite cells
Repair and Regeneration
rapid in smooth muscle because the cells/fibers are small and relatively less differentiated
Regeneration
Cardiac muscle lacks?
satellite cells
filled with interstitial fluid
Transverse tubules
Test your knowledge of muscle tissue cell structures, including single cell contractile units and multicellular contractile units. Explore the cytoplasm of muscle cells and components of secretory glands.
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