Podcast
Questions and Answers
What percentage of patients in the PONOS study underwent joint replacement procedures?
What percentage of patients in the PONOS study underwent joint replacement procedures?
- 15%
- 23% (correct)
- 38%
- 50%
What is the significance of the annual medical examinations cost for OA patients in Greece?
What is the significance of the annual medical examinations cost for OA patients in Greece?
- It is not a significant expense for moderate to severe OA patients.
- It accounts for almost half of the National Health Insurance contributions.
- It is included in the total annual cost calculations. (correct)
- It can reach up to €500 per patient.
Which of the following is NOT identified as an unmet need in osteoarthritis management?
Which of the following is NOT identified as an unmet need in osteoarthritis management?
- Stronger enforcement of medical regulations (correct)
- Early diagnosis and management
- Innovation in treatment
- Public health interventions
What is the total annual financial impact of osteoarthritis on a single patient?
What is the total annual financial impact of osteoarthritis on a single patient?
Which of the following was highlighted as a key cost component in the private contributions for OA patients?
Which of the following was highlighted as a key cost component in the private contributions for OA patients?
Which treatments are suggested to potentially lower the need for joint replacements?
Which treatments are suggested to potentially lower the need for joint replacements?
How significant is the expected cost of caregiving for moderate to severe OA patients annually?
How significant is the expected cost of caregiving for moderate to severe OA patients annually?
What critical role does early diagnosis and management play in treating osteoarthritis?
What critical role does early diagnosis and management play in treating osteoarthritis?
What annual average contribution does the National Health Insurance Fund make per patient for treating osteoarthritis?
What annual average contribution does the National Health Insurance Fund make per patient for treating osteoarthritis?
What is a primary factor driving the prevalence of osteoarthritis according to the study?
What is a primary factor driving the prevalence of osteoarthritis according to the study?
What was the primary aim of the PONOS study?
What was the primary aim of the PONOS study?
How many patients were included in the PONOS study?
How many patients were included in the PONOS study?
Which of the following treatments had patients failed to tolerate in the PONOS study?
Which of the following treatments had patients failed to tolerate in the PONOS study?
What was the total average direct cost per patient annually identified in the PONOS study?
What was the total average direct cost per patient annually identified in the PONOS study?
Which indirect cost was found to be the most significant in the PONOS study?
Which indirect cost was found to be the most significant in the PONOS study?
What percentage of patients reported requiring private caregiving in the study?
What percentage of patients reported requiring private caregiving in the study?
Which healthcare site characteristic was part of the PONOS study design?
Which healthcare site characteristic was part of the PONOS study design?
What age group did the PONOS study focus on for its patient sample?
What age group did the PONOS study focus on for its patient sample?
What were the Kellgren-Lawrence grades of osteoarthritis included in the PONOS study?
What were the Kellgren-Lawrence grades of osteoarthritis included in the PONOS study?
What is the estimated ratio of indirect costs to direct costs for osteoarthritis patients according to the study?
What is the estimated ratio of indirect costs to direct costs for osteoarthritis patients according to the study?
Flashcards
What is the main objective of the PONOS study?
What is the main objective of the PONOS study?
The PONOS study focused on assessing the financial burden of moderate to severe osteoarthritis (OA) on individuals and the Greek healthcare system.
How was the PONOS study conducted?
How was the PONOS study conducted?
The study analyzed data from 164 patients with moderate to severe OA of the hip or knee, focusing on real-world data through a non-interventional, cross-sectional, and prospective approach.
Who were the participants in PONOS?
Who were the participants in PONOS?
The study involved 164 participants aged 18 years or older, with confirmed, moderate to severe OA in the hip or knee, based on Kellgren-Lawrence grades 3-4.
What were the conditions of the participants in PONOS?
What were the conditions of the participants in PONOS?
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Where did the PONOS research take place?
Where did the PONOS research take place?
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What are the main cost categories in PONOS?
What are the main cost categories in PONOS?
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What are the average direct costs in PONOS?
What are the average direct costs in PONOS?
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What are the average indirect costs in PONOS?
What are the average indirect costs in PONOS?
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What is the key takeaway regarding indirect costs in PONOS?
What is the key takeaway regarding indirect costs in PONOS?
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What are the major cost drivers identified in PONOS?
What are the major cost drivers identified in PONOS?
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What is the economic significance of joint replacement procedures in treating osteoarthritis?
What is the economic significance of joint replacement procedures in treating osteoarthritis?
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How does osteoarthritis impact the Greek healthcare system?
How does osteoarthritis impact the Greek healthcare system?
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What unmet needs exist in osteoarthritis treatment?
What unmet needs exist in osteoarthritis treatment?
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What are some of the risk factors associated with osteoarthritis?
What are some of the risk factors associated with osteoarthritis?
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Why is early diagnosis and management crucial in osteoarthritis?
Why is early diagnosis and management crucial in osteoarthritis?
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What is the financial impact of osteoarthritis on patients?
What is the financial impact of osteoarthritis on patients?
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How can healthcare innovation address the economic burden of osteoarthritis?
How can healthcare innovation address the economic burden of osteoarthritis?
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How can advanced treatments reduce healthcare costs in osteoarthritis management?
How can advanced treatments reduce healthcare costs in osteoarthritis management?
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How can healthcare institutions leverage innovation in osteoarthritis management?
How can healthcare institutions leverage innovation in osteoarthritis management?
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What overall strategies can be implemented to address the challenges of osteoarthritis?
What overall strategies can be implemented to address the challenges of osteoarthritis?
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Study Notes
PONOS Study: Economic Burden of Osteoarthritis in Greece
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Study Objective: Assess the economic impact of moderate to severe osteoarthritis (OA) on patients and the Greek healthcare system. Analyzed data from 164 patients across 9 Greek healthcare sites. Used a non-interventional, cross-sectional, prospective design.
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Study Participants: Patients (18 years and older) with moderate to severe OA (Kellgren-Lawrence grades 3-4) of hip or knee. Patients had failed or couldn't tolerate treatment with paracetamol, NSAIDs, or opioids. Recruited from 9 Greek sites between April and November 2021.
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Cost Drivers (Direct):
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Medical Visits: €813.4 annually (avg. per patient), including physiotherapy, equipment, and diagnostic imaging (X-rays, MRI).
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Joint Replacement Surgery (JR): €4,326.3 annually (avg. per patient) for those undergoing procedures. 38 patients (23%) had JR.
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Paid Care: €9,360 annually (avg. per patient) for those needing private caregiving. 4 patients (2.5%) fell in this category.
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Average Total Direct Costs: €1,675.3 annually per patient.
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Cost Drivers (Indirect):
- Lost Productivity: €3,501.4 annually (avg. per patient) due to absenteeism (sick leave) and presenteeism (reduced productivity from chronic pain).
- Indirect costs (disability compensation, early retirement) were estimated to be possibly four times higher than direct costs.
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Significance of Joint Replacement Surgery:
- Represents a major cost component (€4,326.3 annually).
- Important procedure for end-stage OA but a significant financial burden, especially in Greece due to reliance on private funding.
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Impact on the Greek Healthcare System:
- Public Funding (e.g., NOPHS): €813.4 annual contribution per patient (covering medical examinations, physiotherapy, and equipment).
- Private Funding: Significant costs for private caregiving (up to €9,360 annually per patient), impacting patients and families. Unpaid caregiving reduces formal costs but increases indirect burdens.
- Overall: Combined public and private funding underlines the need for affordable, innovative treatments to reduce costs and improve outcomes.
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Unmet Needs in Osteoarthritis Management:
- Treatment Innovation: Focus on solutions for joint regeneration to reduce reliance on costly procedures like joint replacements.
- Public Health Interventions: Address risk factors such as obesity and aging to curtail OA prevalence.
- Early Diagnosis and Management: Timely, effective interventions to minimize long-term costs and improve patient outcomes.
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Total Financial Impact per Patient:
- Combined Direct and Indirect Costs: €5,176.7 annually per patient.
- Patients requiring joint replacement or paid caregiving have costs significantly exceeding €9,360 per year per patient. Indicates critical need for innovative cost-effective solutions like new technologies.
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Leveraging Findings for Healthcare Innovation:
- Advanced Treatments Introduction: Technologies like ORMI and BioEnthesis could reduce the procedure burden and related costs.
- Decreasing Costs: Reducing procedures, shorter hospital stays, and improved patient recovery would decrease direct and indirect costs.
- Strategic Partnerships: Hospitals can partner with insurers and incorporate these technologies for improved orthopedic care.
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