Dyslipidemia and Cholesterol Quiz
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Questions and Answers

Which lipoprotein transports triglycerides from the liver to peripheral tissue?

  • Very low density lipoprotein (VLDL) (correct)
  • High density lipoprotein (HDL)
  • Low density lipoprotein (LDL)
  • Chylomicrons
  • What is the main function of high density lipoprotein (HDL) cholesterol?

  • Transports cholesterol to the liver for breakdown (correct)
  • Transports triglycerides to peripheral tissue
  • Accumulates in blood vessel walls
  • Transports cholesterol to tissues
  • What type of fatty acid has the maximum number of hydrogen atoms?

  • Polyunsaturated
  • Trans
  • Saturated (correct)
  • Monounsaturated
  • Which equation represents the calculation of low density lipoprotein (LDL) cholesterol?

    <p>$LDL = Total hinspace cholesterol - HDL - (TG imes 0.2)$</p> Signup and view all the answers

    Which type of statin is known to be tissue selective in the liver but not in other tissues?

    <p>Simvastatin</p> Signup and view all the answers

    Which statin is easier to synthesize?

    <p>Type 2 statins</p> Signup and view all the answers

    Which statin is metabolized by CYP3A4?

    <p>Atorvastatin</p> Signup and view all the answers

    Which statin is known to have little metabolism by CYP enzymes?

    <p>Pravastatin</p> Signup and view all the answers

    Which medication is known to inhibit intestinal absorption of dietary and biliary cholesterol without inhibiting cholesterol synthesis?

    <p>Ezetimibe</p> Signup and view all the answers

    Which class of drugs stimulate peroxisome proliferator-activated receptor type α nuclear receptors in the liver?

    <p>Fibrates</p> Signup and view all the answers

    Which medication is administered every few weeks by injection and increases LDL-C uptake by the liver?

    <p>Evolocumab</p> Signup and view all the answers

    Which type of statin is known to have high lipophilicity at its active form?

    <p>Cerivastatin</p> Signup and view all the answers

    Which type of statin is known to have poor selectivity for the liver over peripheral tissue?

    <p>Cerivastatin</p> Signup and view all the answers

    Which medication inhibits reabsorption of bile acids from the intestine, leading to increased uptake of cholesterol from the blood by the liver?

    <p>Cholestyramine</p> Signup and view all the answers

    Which medication must be used with extreme caution or stopped when potent CYP3A4 inhibitors are being used?

    <p>Simvastatin</p> Signup and view all the answers

    Which medication is known to decrease total cholesterol, LDL, and HDL without inhibiting cholesterol synthesis?

    <p>Ezetimibe</p> Signup and view all the answers

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