16 Questions
Which lipoprotein transports triglycerides from the liver to peripheral tissue?
Very low density lipoprotein (VLDL)
What is the main function of high density lipoprotein (HDL) cholesterol?
Transports cholesterol to the liver for breakdown
What type of fatty acid has the maximum number of hydrogen atoms?
Saturated
Which equation represents the calculation of low density lipoprotein (LDL) cholesterol?
$LDL = Total hinspace cholesterol - HDL - (TG imes 0.2)$
Which type of statin is known to be tissue selective in the liver but not in other tissues?
Simvastatin
Which statin is easier to synthesize?
Type 2 statins
Which statin is metabolized by CYP3A4?
Atorvastatin
Which statin is known to have little metabolism by CYP enzymes?
Pravastatin
Which medication is known to inhibit intestinal absorption of dietary and biliary cholesterol without inhibiting cholesterol synthesis?
Ezetimibe
Which class of drugs stimulate peroxisome proliferator-activated receptor type α nuclear receptors in the liver?
Fibrates
Which medication is administered every few weeks by injection and increases LDL-C uptake by the liver?
Evolocumab
Which type of statin is known to have high lipophilicity at its active form?
Cerivastatin
Which type of statin is known to have poor selectivity for the liver over peripheral tissue?
Cerivastatin
Which medication inhibits reabsorption of bile acids from the intestine, leading to increased uptake of cholesterol from the blood by the liver?
Cholestyramine
Which medication must be used with extreme caution or stopped when potent CYP3A4 inhibitors are being used?
Simvastatin
Which medication is known to decrease total cholesterol, LDL, and HDL without inhibiting cholesterol synthesis?
Ezetimibe
Test your knowledge of dyslipidemia and cholesterol with this quiz. Explore the roles of lipoproteins like VLDL and LDL in transporting triglycerides and cholesterol. Learn about the potential risks associated with the accumulation of LDL cholesterol in blood vessels and its impact on cardiovascular health.
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