Dysentery Causes and Types
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Questions and Answers

What is the primary therapy for symptomatic amebiasis?

  • Washing vegetables to get rid of cyst
  • Desiccation and exposure to temperature above 50°C (122°F)
  • Education of known carriers for thorough washing after defecation
  • Hydration and the use of metronidazole and/or tinidazole (correct)
  • What is the most common climate for Giardia lamblia to occur?

  • Tropical climates
  • Cold climates
  • Temperate climates
  • Warm climates (correct)
  • What is the percentage of patients who experience weight loss in Giardiasis?

  • More than 70%
  • More than 20%
  • More than 50% (correct)
  • More than 30%
  • What is the primary mode of transmission of Giardiasis?

    <p>Swallowing contaminated food or water</p> Signup and view all the answers

    What is the purpose of educating known carriers in Amebiasis control?

    <p>To inform them of the need for thorough washing after defecation</p> Signup and view all the answers

    What is the primary source of Giardia contamination?

    <p>Feces from infected humans or animals</p> Signup and view all the answers

    What is the morbidity rate of Giardiasis?

    <p>Up to 20%</p> Signup and view all the answers

    What is a common symptom of Giardiasis?

    <p>Diarrhea</p> Signup and view all the answers

    What is the consequence of chronic Giardiasis in immunodeficient individuals?

    <p>Decreased lifespan</p> Signup and view all the answers

    What is a possible outcome of Giardiasis infection in children?

    <p>Failure to thrive</p> Signup and view all the answers

    Study Notes

    Dysentery

    • Caused by bacteria Shigella, resulting in shigellosis
    • Can also be caused by other bacteria, protozoa, or parasitic worms
    • Bacillary dysentery is characterized by severe diarrhea containing blood or mucus
    • Caused by gram-negative, facultatively anaerobic, non-motile rods of the genus Shigella

    Shigellosis

    • Estimated 150 million illnesses and 14,000 deaths worldwide
    • Endemic in tropical and temperate climates
    • S. dysenteriae type 1 causes the most severe disease and largest outbreaks
    • Other species include S. Flexneri, S. Sonnei, and S. Boydii
    • Most important cause of acute bloody diarrhea

    Susceptibility and Transmission

    • Immunity after infection is short and unsteady, with no cross-immunity
    • High-risk groups include:
      • Children under 5 years
      • Severely malnourished patients
      • Elderly over 50 years
    • Period of communicability: during acute infection and until the infectious agent is no longer present in feces (usually within 4 weeks)

    Pathogenesis of Shigella

    • Two-stage disease:
      1. Early stage: watery diarrhea and fever due to enterotoxic activity of Shiga toxin
      2. Second stage: adherence to and tissue invasion of the large intestine, resulting in bloody diarrhea and mucosal ulcerations

    Laboratory Findings and Treatment

    • Blood picture: increased total WBC count and neutrophils
    • Stool examination: direct microscopic exam, WBC, RBC, and pus cells
    • Bacteria culture: Shigella species
    • Treatment: rest, fluids, and antimicrobials for severe cases; hospitalization for severely ill or malnourished patients

    Amoebiasis

    • Caused by the intestinal protozoan Entamoeba histolytica
    • Geographic distribution: worldwide, with higher incidence in developing countries
    • Risk groups: male homosexuals, travelers, recent immigrants, and institutionalized populations
    • Incubation period: 2-4 weeks
    • Period of communicability: while E. histolytica cysts are excreted (may continue for years)

    Complications of Amoebiasis

    • Severe ulceration of the gastrointestinal mucosal surfaces
    • Invasion of soft tissues, most commonly the liver
    • Formation of masses (amoebomas) leading to intestinal obstruction
    • Local complications: pericolic and pericaecal abscess, pyogenic liver abscess, and subdiaphragmatic abscess
    • Pulmonary amoebiasis: lung abscess, pulmono-pleural fistula, and empyema
    • Brain abscess and amoebic meningoencephalitis

    Diagnosis and Prevention of Amoebiasis

    • Diagnosis: stool examination, blood tests, proctosigmoidoscopy or colonoscopy
    • Prevention:
      • Sanitary disposal of human feces
      • Safe water supply
      • Proper chlorination of water supply
      • Education on personal hygiene
      • Health supervision of food handlers
      • Flies control
      • Washing vegetables to remove cysts
      • Cysts can be killed by desiccation and high temperatures

    Treatment of Amoebiasis

    • Primary therapy: hydration and metronidazole and/or tinidazole

    Giardiasis

    • Caused by the protozoal parasite Giardia intestinalis
    • Found in humans, domestic animals, and wild animals
    • Occurs worldwide, especially in warm climates
    • Morbidity rate up to 20%
    • Infections often resolve spontaneously, but chronic infections can occur
    • Can be spread through:
      • Contaminated food or water
      • Close contact with infected individuals
      • Traveling to areas with poor sanitation
      • Exposure to contaminated surfaces
      • Animal contact or environments contaminated with feces

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    Description

    This quiz covers the causes of dysentery, including bacterial and parasitic infections, as well as the different types of dysentery such as shigellosis and amoebic dysentery.

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