Drugs Used to Manage Pain
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Questions and Answers

Which of the following ingredients should patients with pseudomembranous colitis avoid?

  • Potassium chloride
  • Zinc
  • Calcium (correct)
  • Sodium bicarbonate (correct)
  • What is one of the major adverse reactions in the gastrointestinal system from antacid use?

  • Fatigue
  • Diarrhea
  • Constipation (correct)
  • Headache
  • Which category does Loperamide fall under during pregnancy?

  • Category D
  • Category B (correct)
  • Category A
  • Category C
  • What are common symptoms indicated for the use of antacids?

    <p>Heartburn symptoms in GERD</p> Signup and view all the answers

    Which type of drug may result in decreased absorption when administered with antacids?

    <p>Acidic drugs</p> Signup and view all the answers

    What is a common adverse reaction affecting the central nervous system from antacids?

    <p>Euphoria</p> Signup and view all the answers

    Which of the following conditions is NOT indicated for the use of antiflatulents?

    <p>Chronic heart failure</p> Signup and view all the answers

    What effect do antidiarrheal drugs have when combined with antihistamines?

    <p>Decrease blood concentration of acidic drugs</p> Signup and view all the answers

    What is the primary function of cathartics in the gastrointestinal (GI) tract?

    <p>To speed up the expulsion of substances</p> Signup and view all the answers

    Which of the following is a significant consideration when assessing a patient for H2 antagonists?

    <p>Presence of renal or hepatic impairment</p> Signup and view all the answers

    What characteristic distinguishes bulk forming laxatives from other types?

    <p>They are considered mild laxatives.</p> Signup and view all the answers

    Which of the following would not be relevant when performing a physical examination prior to therapy?

    <p>Personal preferences for medication form</p> Signup and view all the answers

    What should be assessed to prevent potential allergic reactions when administering H2 antagonists?

    <p>History of allergy to any H2 antagonists</p> Signup and view all the answers

    What is the primary risk associated with osmotic laxatives?

    <p>They can produce serious adverse effects.</p> Signup and view all the answers

    What type of medical history is important for assessing a patient's eligibility for H2 antagonists?

    <p>Current status of pregnancy and lactation</p> Signup and view all the answers

    Which statement is true regarding the administration of cathartics with charcoal?

    <p>Charcoal can hasten toxin elimination from the GI tract.</p> Signup and view all the answers

    What is the primary effect of nitroglycerin-derived nitrates?

    <p>Dilate coronary arteries</p> Signup and view all the answers

    Which drug primarily inhibits the absorption of cholesterol in the small intestine?

    <p>Ezetimibe</p> Signup and view all the answers

    What classification does niacin belong to regarding its use in managing lipid levels?

    <p>Antihyperlipidemics</p> Signup and view all the answers

    In which situation should the use of vasodilators be avoided?

    <p>Pregnant women</p> Signup and view all the answers

    Which of the following drugs is typically not used during lactation?

    <p>Nitroglycerin</p> Signup and view all the answers

    What condition is characterized by elevated lipids, specifically cholesterol and triglycerides in the bloodstream?

    <p>Hyperlipidemia</p> Signup and view all the answers

    What is the main therapeutic use of antihyperlipidemic drugs?

    <p>Reduce cholesterol levels</p> Signup and view all the answers

    What role do antihypertensive drugs play in patient care?

    <p>Lower blood pressure</p> Signup and view all the answers

    What is the primary way that guaifenesin is excreted from the body?

    <p>Primarily by the kidneys</p> Signup and view all the answers

    Which of the following conditions requires caution when using guaifenesin?

    <p>Pregnancy or lactation</p> Signup and view all the answers

    What is the primary therapeutic use of guaifenesin?

    <p>To make mucus easier to cough up</p> Signup and view all the answers

    What adverse effect is associated with topical nasal decongestants?

    <p>Rebound congestion</p> Signup and view all the answers

    Which patient condition requires careful monitoring when using guaifenesin?

    <p>Lesion or erosion in the mucous membrane</p> Signup and view all the answers

    In which patients are ACE inhibitors contraindicated?

    <p>Patients with a history of angioedema</p> Signup and view all the answers

    What adverse reaction is NOT commonly associated with ACE inhibitors?

    <p>Increased appetite</p> Signup and view all the answers

    What should be monitored when prescribing ACE inhibitors with potassium supplements?

    <p>Potassium levels</p> Signup and view all the answers

    What is a serious warning associated with Captopril?

    <p>Risk of fetal/neonatal morbidity/mortality if used in pregnancy</p> Signup and view all the answers

    Which of the following is NOT an HMG-CoA Reductase Inhibitor?

    <p>Captopril</p> Signup and view all the answers

    What should a patient taking an ACE inhibitor be warned to avoid?

    <p>Potassium-containing salt substitutes</p> Signup and view all the answers

    Which condition might require the withholding of the ACE inhibitor dose?

    <p>Leukopenia</p> Signup and view all the answers

    What should be given one hour before meals when taking specific ACE inhibitors?

    <p>Captopril and Moexipril</p> Signup and view all the answers

    Which of the following is an example of an ACE inhibitor?

    <p>Benazepril</p> Signup and view all the answers

    What is the primary action of Angiotensin II Receptor Blockers?

    <p>They relax veins and arteries.</p> Signup and view all the answers

    Which mechanism do calcium-channel blockers use to decrease blood pressure?

    <p>They inhibit calcium ion movement across cell membranes.</p> Signup and view all the answers

    What effect do bile acid resins have on cholesterol?

    <p>They bind to bile acids and decrease cholesterol levels.</p> Signup and view all the answers

    Which group of antihypertensive agents significantly decreases cardiac workload?

    <p>Calcium Channel Blockers</p> Signup and view all the answers

    What is a possible contraindication for using calcium-channel blockers?

    <p>Renal impairment</p> Signup and view all the answers

    Which of the following statements is incorrect about ACE inhibitors?

    <p>They significantly increase calcium influx.</p> Signup and view all the answers

    How do ACE inhibitors assist in treating heart failure?

    <p>By reducing preload and afterload on the heart.</p> Signup and view all the answers

    Study Notes

    Drugs Used to Manage Pain

    • Pain is a general term describing uncomfortable sensations. It ranges from mild to severe, and can be acute (short-term) or chronic (long-term).
    • Nociceptive pain results from tissue injury (e.g., arthritis, back pain).
    • Inflammatory pain arises from inappropriate immune system responses (e.g., gout, rheumatoid arthritis).
    • Neuropathic pain stems from nerve irritation (e.g., neuropathy, radicular pain).
    • Functional pain lacks an obvious origin (e.g., fibromyalgia, irritable bowel syndrome).

    Pain Perception Pathway

    • Pain perception involves complex signaling pathways beginning in the periphery, ascending through the spinal cord or brainstem, and ultimately interpreted in the brain's cortex.
    • Key stages: transduction, transmission, modulation, and perception.

    Characteristics of Pain

    • Provocation and Palliation: Identify what triggers the pain and what relieves it.
    • Quality/Quantity: Describe the pain sensation (e.g., sharp, dull, stabbing).
    • Region/Radiation: Specify the location and if the pain spreads.
    • Severity Scale: Rate pain on a scale (e.g., 1-10).
    • Timing: Note time of day, activity, weather, position, etc., when pain changes in severity.

    Pain Assessment

    • A thorough evaluation of pain, including patient experience, factors influencing pain expression, and nursing assessment barriers.

    Comparative Pain Scale Chart

    • Categorizes pain levels from pain-free to excruciating. Pain is rated and described in detail for proper patient management.

    Nonopioid Analgesics

    • Include NSAIDs and paracetamol (acetaminophen).
    • NSAIDs have strong anti-inflammatory, analgesic, and antipyretic effects.
    • Paracetmol is a safe, effective pain reliever and fever reducer, typically used for mild to moderate pain, available over-the-counter or via prescription (in combination).

    Opioid Analgesics

    • Used for severe pain, for both short-term and long-term relief.
    • Opioids are prescribed only.

    Patient-Controlled Analgesia (PCA)

    • Allows patients to self-administer pain medication using a programmable machine.
    • Primarily for patients requiring parenteral analgesia, with incident pain, or patients where oral/transdermal/rectal routes are not used.

    Gastrointestinal Agents

    • Antidiarrheals: Reduce peristalsis and increase intestinal transit time, used for diarrhea symptom relief (contraindicated in specific conditions).
    • Antiflatulents: Relieve or prevent excessive intestinal gas, often using simethicone to coalesce gas bubbles for easier release.
    • Laxatives: Accelerate fecal passage or decrease consistency, primarily used for constipation, with various types (stool softeners, cathartics, etc.).
    • Antacids: Neutralize stomach acid, used for indigestion and heartburn, but can interfere with absorption of other drugs.
    • H2-Receptor Antagonists: Reduce stomach acid production, used for ulcers, GERD and other acid-related conditions.
    • Detailed actions, classifications, and nursing considerations are present for each category.

    Cardiovascular Drugs

    • Antiarrhythmic drugs: Treat irregular heart rhythms by restoring normal heart electrical activity.
    • Cardiac stimulants: Increase heart rate and contractility.
    • Cardiac depressants: Reduce heartbeat and contraction force, decreasing cardiac output.
    • Antihyperlipidemic drugs: Treat high cholesterol (hyperlipidemia). Statins are a common class of these drugs.
    • Bile acid resins: Bind to bile acids, increasing cholesterol production and excretion in the feces.
    • Fibric acid derivatives: Treat high cholesterol, mainly by lowering triglycerides and increasing metabolism of very low-density lipoproteins.
    • Coronary vasodilators: Open coronary arteries to increase blood flow, often used for angina.
    • HMG-CoA reductase inhibitors (statins): Inhibit cholesterol production; used with a diet low in saturated fat.

    Respiratory Agents

    • Antitussives: Suppress coughs, acting directly on the brain’s cough center.
    • Antihistamines: Treat allergic rhinitis (hay fever), hives, and other allergies (first and second generation).
    • Mucolytics: Thin respiratory secretions, making them easier to cough up.
    • Expectorants: Increase airway water to aid mucus clearing.
    • Decongestants: Reduce congestion by causing local blood vessel constriction.
    • Bronchodilators: Relax lung muscles and widen airways, used for asthma and other lung conditions.
    • Antiasthmatic drugs: Treat and prevent asthma attacks. These include bronchodilators, corticosteroids, and cromolyn.

    Anticoagulants and Antiplatelets

    • Anticoagulants: Prevent blood clot formation, mainly for people at high risk of stroke or heart attack.
    • Antiplatelets: Prevent platelets (blood cells) from clumping together, forming clots; aspirin is most common.

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    Related Documents

    Unit 3 Pharmacology PDF

    Description

    This quiz explores the various types of pain and the drugs used to manage them. It covers nociceptive, inflammatory, neuropathic, and functional pain along with the pain perception pathways. Test your knowledge on pain characteristics and management strategies.

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