Podcast
Questions and Answers
What is the primary indication for using triptans like sumatriptan?
What is the primary indication for using triptans like sumatriptan?
- Treating allergic reactions
- Managing chronic pain disorders
- Terminating migraine attacks (correct)
- Providing relief for severe headache
Which of the following is a possible method of administration for sumatriptan?
Which of the following is a possible method of administration for sumatriptan?
- Intravenous infusion
- Oral only
- Nasal inhalation (correct)
- Topical ointment
Which combination is marketed as a treatment for migraines that includes acetaminophen?
Which combination is marketed as a treatment for migraines that includes acetaminophen?
- Pain Relief Max
- Tylenol Complete
- Excedrin migraine (correct)
- Migraine Away
What should be avoided in patients with risk factors for coronary artery disease (CAD) when prescribing sumatriptan?
What should be avoided in patients with risk factors for coronary artery disease (CAD) when prescribing sumatriptan?
What is a common side effect of sumatriptan?
What is a common side effect of sumatriptan?
When is the use of opioid analgesics recommended for migraine treatment?
When is the use of opioid analgesics recommended for migraine treatment?
Which of the following medications are effective in combination with aspirin for migraine relief?
Which of the following medications are effective in combination with aspirin for migraine relief?
Which of the following best describes the action mechanism of triptans on migraines?
Which of the following best describes the action mechanism of triptans on migraines?
What is a potential effect of overdosing with certain medications as indicated in the content?
What is a potential effect of overdosing with certain medications as indicated in the content?
Which of the following symptoms could be indicative of severe adverse effects from a medication listed?
Which of the following symptoms could be indicative of severe adverse effects from a medication listed?
What underlying condition might contra-indicate the use of specific triptans as suggested in the content?
What underlying condition might contra-indicate the use of specific triptans as suggested in the content?
In the context provided, what is likely true about the use of triptans in older adults?
In the context provided, what is likely true about the use of triptans in older adults?
Which of the following is a significant consideration when prescribing medications associated with the content?
Which of the following is a significant consideration when prescribing medications associated with the content?
What is the primary mechanism of action of Methylnaltrexone?
What is the primary mechanism of action of Methylnaltrexone?
Which of the following is considered a significant risk when using Naloxegol?
Which of the following is considered a significant risk when using Naloxegol?
What is a common side effect associated with Methylnaltrexone administration?
What is a common side effect associated with Methylnaltrexone administration?
In which population does Methylnaltrexone have a specific consideration according to Beers Criteria?
In which population does Methylnaltrexone have a specific consideration according to Beers Criteria?
What route of administration is NOT typically used for Naloxegol?
What route of administration is NOT typically used for Naloxegol?
Which of the following is an important contraindication for the use of Naloxegol?
Which of the following is an important contraindication for the use of Naloxegol?
What type of patients benefit most from Naloxegol?
What type of patients benefit most from Naloxegol?
Which common gastrointestinal symptom is Naloxegol used to alleviate?
Which common gastrointestinal symptom is Naloxegol used to alleviate?
What is the classification of Tapentadol?
What is the classification of Tapentadol?
Which of the following is a key teaching point regarding Tapentadol's potential side effects?
Which of the following is a key teaching point regarding Tapentadol's potential side effects?
What is a recommended precaution when administering Tapentadol?
What is a recommended precaution when administering Tapentadol?
What is the mechanism of action (MOA) of Tapentadol?
What is the mechanism of action (MOA) of Tapentadol?
Which of the following combinations should be avoided when taking Tapentadol?
Which of the following combinations should be avoided when taking Tapentadol?
What is a common consideration in the management plan when prescribing Tapentadol?
What is a common consideration in the management plan when prescribing Tapentadol?
Which patient population is particularly at risk for side effects from Tapentadol?
Which patient population is particularly at risk for side effects from Tapentadol?
Which statement about teaching patients regarding Tapentadol is false?
Which statement about teaching patients regarding Tapentadol is false?
Which of the following is a common treatment for acute otitis media?
Which of the following is a common treatment for acute otitis media?
What is the primary function of topical glucocorticoids?
What is the primary function of topical glucocorticoids?
Which of the following is the primary condition treated with mupirocin?
Which of the following is the primary condition treated with mupirocin?
What dosage form is clindamycin available in?
What dosage form is clindamycin available in?
Which of the following medications is most commonly indicated for treating acne?
Which of the following medications is most commonly indicated for treating acne?
What is the primary mechanism of action of keratolytic agents?
What is the primary mechanism of action of keratolytic agents?
What is an effective treatment for allergic conjunctivitis?
What is an effective treatment for allergic conjunctivitis?
Which of the following agents is often used for wart removal?
Which of the following agents is often used for wart removal?
What is the recommended pediatric dosage for cephalexin?
What is the recommended pediatric dosage for cephalexin?
Which class of drug is commonly associated with reducing skin inflammation and irritation?
Which class of drug is commonly associated with reducing skin inflammation and irritation?
Which of the following medications is a combination drug containing hydrocodone?
Which of the following medications is a combination drug containing hydrocodone?
Which condition is characterized by the presence of fluid in the middle ear?
Which condition is characterized by the presence of fluid in the middle ear?
What is the main concern for patients with hepatic impairment when taking drugs metabolized by CYP450 enzymes?
What is the main concern for patients with hepatic impairment when taking drugs metabolized by CYP450 enzymes?
What does 'BBW' stand for in relation to medications?
What does 'BBW' stand for in relation to medications?
Which of the following is primarily used to treat fungal infections of the ear?
Which of the following is primarily used to treat fungal infections of the ear?
Which of these medications is contraindicated for patients with a known allergy to penicillin?
Which of these medications is contraindicated for patients with a known allergy to penicillin?
Which of the following patient groups requires special consideration when prescribing hydrocodone?
Which of the following patient groups requires special consideration when prescribing hydrocodone?
What potential interaction should be monitored when taking hydrocodone?
What potential interaction should be monitored when taking hydrocodone?
Which metabolic pathway is primarily involved in the metabolism of hydrocodone?
Which metabolic pathway is primarily involved in the metabolism of hydrocodone?
What additional substance is commonly combined with hydrocodone in pain management?
What additional substance is commonly combined with hydrocodone in pain management?
What is a common side effect of hydrocodone use?
What is a common side effect of hydrocodone use?
Which age group is particularly vulnerable to adverse effects of hydrocodone?
Which age group is particularly vulnerable to adverse effects of hydrocodone?
What should be monitored in patients who are breastfeeding and taking hydrocodone?
What should be monitored in patients who are breastfeeding and taking hydrocodone?
Flashcards
Migraine Abortive Therapy
Migraine Abortive Therapy
Drugs used to stop a migraine attack.
NSAIDs for Migraine
NSAIDs for Migraine
Nonsteroidal anti-inflammatory drugs (like aspirin, naproxen) can help mild-moderate migraines.
Triptans (e.g., Sumatriptan)
Triptans (e.g., Sumatriptan)
First-line drugs for stopping migraine attacks by constricting blood vessels.
Sumatriptan Administration
Sumatriptan Administration
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Opioid Analgesics for Migraines
Opioid Analgesics for Migraines
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Sumatriptan Precautions
Sumatriptan Precautions
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Drug Interactions (Triptans)
Drug Interactions (Triptans)
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Excedrin Migraine
Excedrin Migraine
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Hydrocodone Combination Drugs
Hydrocodone Combination Drugs
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Hydrocodone/APAP (Norco, Vicodin, Lortab )
Hydrocodone/APAP (Norco, Vicodin, Lortab )
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Extended-release formulations (ER)
Extended-release formulations (ER)
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Schedule II agents
Schedule II agents
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Acetaminophen (APAP) content
Acetaminophen (APAP) content
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Pregnaency and Hydrocodone
Pregnaency and Hydrocodone
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Geriatric patients and Hydrocodone
Geriatric patients and Hydrocodone
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Mild to Moderate Pain
Mild to Moderate Pain
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Children and Hydrocodone
Children and Hydrocodone
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Hepatic function and Hydrocodone
Hepatic function and Hydrocodone
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Glaucoma treatment
Glaucoma treatment
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Allergic Conjunctivitis
Allergic Conjunctivitis
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Topical drugs (skin)
Topical drugs (skin)
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Topical Glucocorticoids (skin)
Topical Glucocorticoids (skin)
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Keratolytic agents
Keratolytic agents
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Acne treatment (topical)
Acne treatment (topical)
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Acne treatment (oral)
Acne treatment (oral)
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Sunscreens
Sunscreens
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Atopic dermatitis (eczema)
Atopic dermatitis (eczema)
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Wart removal agents
Wart removal agents
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Mupirocin (Bactroban)
Mupirocin (Bactroban)
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Otitis Media
Otitis Media
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Acute Otitis Externa (AOE)
Acute Otitis Externa (AOE)
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Topical Antibiotic (skin)
Topical Antibiotic (skin)
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Tapentadol (Nucynta)
Tapentadol (Nucynta)
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Tapentadol: Mechanism of Action
Tapentadol: Mechanism of Action
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Tapentadol: Monitoring
Tapentadol: Monitoring
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Tapentadol: Contraindication
Tapentadol: Contraindication
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Tapentadol: DDI (Drug Interaction)
Tapentadol: DDI (Drug Interaction)
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Tapentadol: Teaching Points
Tapentadol: Teaching Points
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Tapentadol: Side Effects
Tapentadol: Side Effects
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Tapentadol: Black Box Warning
Tapentadol: Black Box Warning
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Cluster Headaches
Cluster Headaches
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Triptans
Triptans
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What are some common side effects of triptans?
What are some common side effects of triptans?
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What are contraindications for triptans?
What are contraindications for triptans?
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Why are triptans used for migraine?
Why are triptans used for migraine?
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Methylnaltrexone (Relistor)
Methylnaltrexone (Relistor)
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Naloxegol (Movantik)
Naloxegol (Movantik)
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Naldemedine (Symproic)
Naldemedine (Symproic)
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Opioid receptor blockers for constipation
Opioid receptor blockers for constipation
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Hepatic function and opioid receptor blockers
Hepatic function and opioid receptor blockers
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Children and opioid receptor blockers
Children and opioid receptor blockers
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Pregnancy and opioid receptor blockers
Pregnancy and opioid receptor blockers
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Opioid receptor blockers and DDI
Opioid receptor blockers and DDI
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Study Notes
Drugs for Pain
- Opioid analgesics, opioid antagonists, and nonopioid centrally acting analgesics are used to treat pain.
- Nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin, naproxen, and diclofenac can relieve mild to moderate migraines. Aspirin combined with metoclopramide may be as effective as sumatriptan. Acetaminophen, aspirin, and caffeine (Excedrin Migraine) are sometimes used, but should be combined with other drugs appropriately. Opioids are reserved for severe migraines not responding to first-line medications, with butorphanol nasal spray as an example.
- Triptans (serotonin 1B/1D receptor agonists) are first-line drugs for terminating migraine attacks. They work by constricting intracranial blood vessels and suppressing inflammatory neuropeptides.
- Sumatriptan is available orally, nasally, or by injection and can abort ongoing migraine attacks. It also comes in a combination with naproxen.
- Sumatriptan is generally well-tolerated, with mild, transient side effects. Sumatriptan should be avoided in patients with CAD risk factors until ruled out; it is also not recommended during pregnancy.
- Drug interactions exist between ergot alkaloids and other triptans because they all cause vasoconstriction.
Drugs for the Eye
- Drugs are used to manage glaucoma
- Details about pathophysiology of glaucoma and treatment overview are missing from the provided text.
- Specific drugs, dosages, and administration routes for glaucoma management are missing.
- Information on allergic conjunctivitis and additional ophthalmic drugs are also missing.
Drugs for the Skin
- Skin anatomy is missing.
- Various topical drugs for skin conditions, such as topical glucocorticoids, keratolytic agents, and acne treatments (topical and oral) are mentioned.
- Sunscreens are also discussed, along with their uses. Atopic dermatitis (eczema), wart removal, and other miscellaneous skin conditions are also mentioned.
Medication Charts (Examples)
- Medication charts provide generic and trade names, formulations, pediatric and adult dosages for various drugs. Examples include mupirocin (Bactroban), retapamulin (Altabax), cephalexin (Keflex), dicloxacillin, clindamycin, amoxicillin/clavulanate.
- Dosage details, including frequency and duration, vary and are specifically outlined for the given drug
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