Pain Management and Drugs Overview

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary indication for using triptans like sumatriptan?

  • Treating allergic reactions
  • Managing chronic pain disorders
  • Terminating migraine attacks (correct)
  • Providing relief for severe headache

Which of the following is a possible method of administration for sumatriptan?

  • Intravenous infusion
  • Oral only
  • Nasal inhalation (correct)
  • Topical ointment

Which combination is marketed as a treatment for migraines that includes acetaminophen?

  • Pain Relief Max
  • Tylenol Complete
  • Excedrin migraine (correct)
  • Migraine Away

What should be avoided in patients with risk factors for coronary artery disease (CAD) when prescribing sumatriptan?

<p>Use until CAD has been ruled out (A)</p> Signup and view all the answers

What is a common side effect of sumatriptan?

<p>Nausea and dizziness (C)</p> Signup and view all the answers

When is the use of opioid analgesics recommended for migraine treatment?

<p>When other treatments have failed (D)</p> Signup and view all the answers

Which of the following medications are effective in combination with aspirin for migraine relief?

<p>Metoclopramide (D)</p> Signup and view all the answers

Which of the following best describes the action mechanism of triptans on migraines?

<p>Constrict intracranial blood vessels (A)</p> Signup and view all the answers

What is a potential effect of overdosing with certain medications as indicated in the content?

<p>Tachycardia (A), Significant bradycardia (B)</p> Signup and view all the answers

Which of the following symptoms could be indicative of severe adverse effects from a medication listed?

<p>Severe angina (A)</p> Signup and view all the answers

What underlying condition might contra-indicate the use of specific triptans as suggested in the content?

<p>History of myocardial infarction (A)</p> Signup and view all the answers

In the context provided, what is likely true about the use of triptans in older adults?

<p>Geriatric doses may require adjustments. (B)</p> Signup and view all the answers

Which of the following is a significant consideration when prescribing medications associated with the content?

<p>The presence of peripheral ischemia. (A)</p> Signup and view all the answers

What is the primary mechanism of action of Methylnaltrexone?

<p>Blockage of opioid receptors (C)</p> Signup and view all the answers

Which of the following is considered a significant risk when using Naloxegol?

<p>Risk of opioid withdrawal (B)</p> Signup and view all the answers

What is a common side effect associated with Methylnaltrexone administration?

<p>Abdominal pain (D)</p> Signup and view all the answers

In which population does Methylnaltrexone have a specific consideration according to Beers Criteria?

<p>Geriatric patients (A)</p> Signup and view all the answers

What route of administration is NOT typically used for Naloxegol?

<p>Intravenous (C)</p> Signup and view all the answers

Which of the following is an important contraindication for the use of Naloxegol?

<p>Concurrent use of CYP3A4 inhibitors (A)</p> Signup and view all the answers

What type of patients benefit most from Naloxegol?

<p>Patients with opioid-induced constipation (B)</p> Signup and view all the answers

Which common gastrointestinal symptom is Naloxegol used to alleviate?

<p>Constipation (C)</p> Signup and view all the answers

What is the classification of Tapentadol?

<p>Schedule II agent (B)</p> Signup and view all the answers

Which of the following is a key teaching point regarding Tapentadol's potential side effects?

<p>It may cause severe respiratory depression. (A)</p> Signup and view all the answers

What is a recommended precaution when administering Tapentadol?

<p>Evaluate renal function before prescribing. (D)</p> Signup and view all the answers

What is the mechanism of action (MOA) of Tapentadol?

<p>Opioid agonist and norepinephrine reuptake inhibitor (B)</p> Signup and view all the answers

Which of the following combinations should be avoided when taking Tapentadol?

<p>Alcohol and Tapentadol (C)</p> Signup and view all the answers

What is a common consideration in the management plan when prescribing Tapentadol?

<p>Daily max dose should be adhered to, based on specific guidelines. (C)</p> Signup and view all the answers

Which patient population is particularly at risk for side effects from Tapentadol?

<p>Elderly patients with renal impairment (C)</p> Signup and view all the answers

Which statement about teaching patients regarding Tapentadol is false?

<p>Patients can use it without any regard to any other medications. (C)</p> Signup and view all the answers

Which of the following is a common treatment for acute otitis media?

<p>Oral antibiotics (D)</p> Signup and view all the answers

What is the primary function of topical glucocorticoids?

<p>Reducing inflammation (A)</p> Signup and view all the answers

Which of the following is the primary condition treated with mupirocin?

<p>Bacterial skin infections (C)</p> Signup and view all the answers

What dosage form is clindamycin available in?

<p>Capsules and suspension (C)</p> Signup and view all the answers

Which of the following medications is most commonly indicated for treating acne?

<p>Amoxicillin (B)</p> Signup and view all the answers

What is the primary mechanism of action of keratolytic agents?

<p>Promoting skin cell turnover (B)</p> Signup and view all the answers

What is an effective treatment for allergic conjunctivitis?

<p>Antihistamines (B)</p> Signup and view all the answers

Which of the following agents is often used for wart removal?

<p>Salicylic acid (D)</p> Signup and view all the answers

What is the recommended pediatric dosage for cephalexin?

<p>6.25 mg/kg (D)</p> Signup and view all the answers

Which class of drug is commonly associated with reducing skin inflammation and irritation?

<p>Topical glucocorticoids (A)</p> Signup and view all the answers

Which of the following medications is a combination drug containing hydrocodone?

<p>Norco (B)</p> Signup and view all the answers

Which condition is characterized by the presence of fluid in the middle ear?

<p>Otitis Media with Effusion (B)</p> Signup and view all the answers

What is the main concern for patients with hepatic impairment when taking drugs metabolized by CYP450 enzymes?

<p>Higher risk of hepatotoxicity (A)</p> Signup and view all the answers

What does 'BBW' stand for in relation to medications?

<p>Black Box Warning (C)</p> Signup and view all the answers

Which of the following is primarily used to treat fungal infections of the ear?

<p>Acetic acid (A)</p> Signup and view all the answers

Which of these medications is contraindicated for patients with a known allergy to penicillin?

<p>Cephalexin (C)</p> Signup and view all the answers

Which of the following patient groups requires special consideration when prescribing hydrocodone?

<p>All of the above (D)</p> Signup and view all the answers

What potential interaction should be monitored when taking hydrocodone?

<p>Interaction with antihistamines (A)</p> Signup and view all the answers

Which metabolic pathway is primarily involved in the metabolism of hydrocodone?

<p>CYP450 3A4 (A)</p> Signup and view all the answers

What additional substance is commonly combined with hydrocodone in pain management?

<p>Acetaminophen (B)</p> Signup and view all the answers

What is a common side effect of hydrocodone use?

<p>Nausea (B)</p> Signup and view all the answers

Which age group is particularly vulnerable to adverse effects of hydrocodone?

<p>Adults aged 60 and above (B)</p> Signup and view all the answers

What should be monitored in patients who are breastfeeding and taking hydrocodone?

<p>Infant sedation levels (C)</p> Signup and view all the answers

Flashcards

Migraine Abortive Therapy

Drugs used to stop a migraine attack.

NSAIDs for Migraine

Nonsteroidal anti-inflammatory drugs (like aspirin, naproxen) can help mild-moderate migraines.

Triptans (e.g., Sumatriptan)

First-line drugs for stopping migraine attacks by constricting blood vessels.

Sumatriptan Administration

Available as oral, nasal spray, and injection forms.

Signup and view all the flashcards

Opioid Analgesics for Migraines

Used for severe migraine that doesn't respond to other treatments.

Signup and view all the flashcards

Sumatriptan Precautions

Avoid in those with heart problems (CAD), and during pregnancy.

Signup and view all the flashcards

Drug Interactions (Triptans)

Ergot alkaloids and other triptans can cause vasoconstriction when taken together.

Signup and view all the flashcards

Excedrin Migraine

A combination of acetaminophen, aspirin, and caffeine, often used for migraine.

Signup and view all the flashcards

Hydrocodone Combination Drugs

Drug combinations containing hydrocodone, often with other pain relievers like APAP (acetaminophen) or ibuprofen, used to treat moderate to severe pain and cough suppression.

Signup and view all the flashcards

Hydrocodone/APAP (Norco, Vicodin, Lortab )

Combination of hydrocodone (a pain reliever) and acetaminophen (APAP) used for pain relief and cough suppression. Available in different forms like immediate-release and extended-release.

Signup and view all the flashcards

Extended-release formulations (ER)

Drug formulations designed to release medication over an extended period, providing a more constant level of relief during the day.

Signup and view all the flashcards

Schedule II agents

Drugs with a high potential for abuse; strict regulations are applied to their prescribing and dispensing.

Signup and view all the flashcards

Acetaminophen (APAP) content

Acetaminophen (APAP) is a common component in combination pain relievers found in most of the listed drugs.

Signup and view all the flashcards

Pregnaency and Hydrocodone

Avoid hydrocodone during pregnancy unless deemed essential by healthcare providers, due to potential harm and side effects to developing fetus.

Signup and view all the flashcards

Geriatric patients and Hydrocodone

Hydrocodone use in elderly patients need special care due to slower metabolism and increased risk of side effects, especially affecting organ function.

Signup and view all the flashcards

Mild to Moderate Pain

Pain that is relatively manageable, doesn't significantly interfere with daily tasks, but warrants suitable treatment options.

Signup and view all the flashcards

Children and Hydrocodone

Hydrocodone use in children is restricted and requires careful monitoring by healthcare professionals.

Signup and view all the flashcards

Hepatic function and Hydrocodone

Hydrocodone affects hepatic (liver) function; patients with liver problems should carefully monitor effects and adjust drug doses accordingly.

Signup and view all the flashcards

Glaucoma treatment

Managing glaucoma involves drugs that lower intraocular pressure.

Signup and view all the flashcards

Allergic Conjunctivitis

Inflammation of the conjunctiva (the membrane lining the eyelids and covering the white part of the eye) often triggered by allergens.

Signup and view all the flashcards

Topical drugs (skin)

Drugs applied directly to the skin's surface for localized treatment.

Signup and view all the flashcards

Topical Glucocorticoids (skin)

Potent anti-inflammatory drugs applied to the skin.

Signup and view all the flashcards

Keratolytic agents

Drugs that cause exfoliation of the skin to remove dead surface cells.

Signup and view all the flashcards

Acne treatment (topical)

External medications used to treat acne.

Signup and view all the flashcards

Acne treatment (oral)

Medications taken by mouth to treat acne.

Signup and view all the flashcards

Sunscreens

Substances applied to the skin to protect against UV radiation.

Signup and view all the flashcards

Atopic dermatitis (eczema)

Chronic skin inflammation characterized by dryness, itching, and rash.

Signup and view all the flashcards

Wart removal agents

Medications used to remove warts from the skin

Signup and view all the flashcards

Mupirocin (Bactroban)

Topical antibiotic used to treat skin infections.

Signup and view all the flashcards

Otitis Media

Inflammation of the middle ear.

Signup and view all the flashcards

Acute Otitis Externa (AOE)

Painful inflammation of the outer ear.

Signup and view all the flashcards

Topical Antibiotic (skin)

Antibiotics that are applied directly to the skin.

Signup and view all the flashcards

Tapentadol (Nucynta)

A Schedule II opioid analgesic used for both acute and chronic pain. It's a centrally acting drug that relieves pain by mimicking the effects of natural opioids.

Signup and view all the flashcards

Tapentadol: Mechanism of Action

Tapentadol works by binding to opioid receptors in the central nervous system, reducing pain signals sent to the brain.

Signup and view all the flashcards

Tapentadol: Monitoring

Patients on Tapentadol need to be monitored carefully for signs of abuse, addiction, and drug interactions. Routine blood tests may be ordered to check for liver function.

Signup and view all the flashcards

Tapentadol: Contraindication

Tapentadol is contraindicated in patients with severe breathing problems, those with a history of opioid addiction, and pregnant women.

Signup and view all the flashcards

Tapentadol: DDI (Drug Interaction)

Tapentadol can have serious interactions with other drugs like alcohol, antidepressants, and other medications. It's crucial to inform your doctor of all medications you're taking.

Signup and view all the flashcards

Tapentadol: Teaching Points

Patients need to understand the risks and benefits of using Tapentadol. Important information includes the necessity to store the medication safely, avoid alcohol, and monitor for potential side effects like drowsiness, nausea, and constipation.

Signup and view all the flashcards

Tapentadol: Side Effects

Common side effects of Tapentadol include nausea, vomiting, constipation, dizziness, drowsiness, and headache. Some people may experience severe side effects like seizures or serious breathing problems.

Signup and view all the flashcards

Tapentadol: Black Box Warning

This medication carries a black box warning due to the potential for misuse, abuse, addiction, and fatal overdose. It's vital to use Tapentadol as prescribed and to only use it for its intended purpose.

Signup and view all the flashcards

Cluster Headaches

Severe, debilitating headaches that occur in groups or clusters, lasting for weeks or months, often with one headache happening every day during that cluster period.

Signup and view all the flashcards

Triptans

Medications used to treat migraine headaches, working by constricting blood vessels in the brain.

Signup and view all the flashcards

What are some common side effects of triptans?

Common side effects include dizziness, drowsiness, fatigue, and tingling in the hands and feet.

Signup and view all the flashcards

What are contraindications for triptans?

Triptans are contraindicated in individuals with coronary artery disease, uncontrolled high blood pressure, and certain types of heart rhythm problems.

Signup and view all the flashcards

Why are triptans used for migraine?

Triptans work by narrowing blood vessels in the brain, which is thought to help relieve the pain of migraines.

Signup and view all the flashcards

Methylnaltrexone (Relistor)

A medication used to treat opioid-induced constipation in adults. It works by blocking opioid receptors in the gut, increasing bowel movements.

Signup and view all the flashcards

Naloxegol (Movantik)

A medication used to treat opioid-induced constipation in adults. It specifically targets opioid receptors in the gut, minimizing effects on the central nervous system.

Signup and view all the flashcards

Naldemedine (Symproic)

A medication used to treat opioid-induced constipation in adults. It works by blocking opioid receptors in the gut, promoting bowel regularity.

Signup and view all the flashcards

Opioid receptor blockers for constipation

These medications are used to combat constipation caused by opioid medications. They selectively block opioid receptors in the gut, relieving constipation symptoms.

Signup and view all the flashcards

Hepatic function and opioid receptor blockers

Patients with liver problems should be monitored closely when taking opioid receptor blockers, as these medications can affect liver function.

Signup and view all the flashcards

Children and opioid receptor blockers

Opioid receptor blockers are generally not used for children due to limited safety and effectiveness data.

Signup and view all the flashcards

Pregnancy and opioid receptor blockers

Use during pregnancy is carefully considered and only when absolutely necessary, as safety data is limited.

Signup and view all the flashcards

Opioid receptor blockers and DDI

These medications can interact with other drugs, especially those that are also affected by liver enzymes.

Signup and view all the flashcards

Study Notes

Drugs for Pain

  • Opioid analgesics, opioid antagonists, and nonopioid centrally acting analgesics are used to treat pain.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin, naproxen, and diclofenac can relieve mild to moderate migraines. Aspirin combined with metoclopramide may be as effective as sumatriptan. Acetaminophen, aspirin, and caffeine (Excedrin Migraine) are sometimes used, but should be combined with other drugs appropriately. Opioids are reserved for severe migraines not responding to first-line medications, with butorphanol nasal spray as an example.
  • Triptans (serotonin 1B/1D receptor agonists) are first-line drugs for terminating migraine attacks. They work by constricting intracranial blood vessels and suppressing inflammatory neuropeptides.
  • Sumatriptan is available orally, nasally, or by injection and can abort ongoing migraine attacks. It also comes in a combination with naproxen.
  • Sumatriptan is generally well-tolerated, with mild, transient side effects. Sumatriptan should be avoided in patients with CAD risk factors until ruled out; it is also not recommended during pregnancy.
  • Drug interactions exist between ergot alkaloids and other triptans because they all cause vasoconstriction.

Drugs for the Eye

  • Drugs are used to manage glaucoma
  • Details about pathophysiology of glaucoma and treatment overview are missing from the provided text.
  • Specific drugs, dosages, and administration routes for glaucoma management are missing.
  • Information on allergic conjunctivitis and additional ophthalmic drugs are also missing.

Drugs for the Skin

  • Skin anatomy is missing.
  • Various topical drugs for skin conditions, such as topical glucocorticoids, keratolytic agents, and acne treatments (topical and oral) are mentioned.
  • Sunscreens are also discussed, along with their uses. Atopic dermatitis (eczema), wart removal, and other miscellaneous skin conditions are also mentioned.

Medication Charts (Examples)

  • Medication charts provide generic and trade names, formulations, pediatric and adult dosages for various drugs. Examples include mupirocin (Bactroban), retapamulin (Altabax), cephalexin (Keflex), dicloxacillin, clindamycin, amoxicillin/clavulanate.
  • Dosage details, including frequency and duration, vary and are specifically outlined for the given drug

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Related Documents

Pharm Exam 5 Study Guide PDF

More Like This

Analgesics and Opioids Quiz
120 questions
Central Nervous System - Analgesics
8 questions
Use Quizgecko on...
Browser
Browser