12 Questions
What is the main purpose of drug therapeutics?
Treat a disease by controlling, improving, or curing the symptoms
What is a possible effect of drugs according to the text?
Not always directed towards a target organ
What is a characteristic of Salbutamol Inhalation Aerosol BP 100mcg/actuation?
Mainly acts on receptors to relax bronchial smooth muscles
Which statement accurately describes the pharmacological action of Salbutamol Inhalation Aerosol?
Rapidly acts to relax bronchial smooth muscles
What is the indication for using Salbutamol Inhalation Aerosol according to the text?
Treatment of bronchospasm in emphysema
In what type of patients should Salbutamol Inhalation Aerosol be used with caution?
Patients who are unusually responsive to sympathomimetic amines
What is the purpose of administering drugs with caution to avoid deleterious effects?
To prevent harmful consequences associated with the drugs
What does the FDA do in response to severe side effects of drugs?
May remove the drug from the market even after approval
What does the term 'therapeutic index' refer to in relation to drugs?
The relationship between a drug's desired therapeutic effects and its adverse effects
What is the main reason for the FDA's proposal to make drug prescribing information easier for doctors to use?
Due to doctors' lack of interest in reading lengthy drug information sheets
What is the significance of a drug's margin of safety or therapeutic index?
It represents the balance between desired therapeutic effects and adverse effects of a drug
What is the main concern that may lead the FDA to remove a drug from the market?
Potential life-threatening cancer treatment issues
Study Notes
Drug Therapeutics
- The main actions of a drug can be to prevent, diagnose, or treat a disease by controlling, improving, or curing symptoms.
Effects of Drugs
- Effects can be directed towards a specific area of the body (target organ) or not.
- Sometimes, the therapeutic effect is actually a side effect.
Side Effects
- Side effects can be mild and temporary, moderate and annoying, or severe.
- The FDA may not approve a drug if the side effects are severe.
- Once approved, side effects must be listed.
Drug Characteristics
- Salbutamol Inhalation Aerosol BP 100mcg/actuation is an example of a drug that relaxes bronchial smooth muscle, with an effect that starts within 5 minutes and lasts for 4-6 hours.
Indications and Dosage
- Salbutamol Inhalation Aerosol BP 100mcg/actuation is used to treat and prevent bronchospasm in emphysema.
Adverse Reactions
- Adverse reactions include dizziness, tremors, and palpitations.
- The drug is contraindicated in patients with a history of hypersensitivity to any of its components.
Pregnancy and Lactation
- The drug should be used with caution during pregnancy and lactation.
Drug Interactions
- The drug should not be used concomitantly with other medications that may interact with it.
Presentation and Storage
- The drug is presented in an aerosol canister and should be stored at room temperature.
Adverse Effects of Drugs
- Adverse effects can be severe and referred to as adverse events.
- These effects may not be apparent until after the drug is on the market.
- The FDA may remove a drug from the market if the adverse effects are severe.
Toxic Effects of Drugs
- Toxic effects occur when a drug's serum levels rise above therapeutic levels.
- The FDA requires drug companies to show that a drug does not produce toxic effects when administered in therapeutic doses.
Margin of Safety
- The relationship between a drug's desired therapeutic effects and its adverse effects is called the drug's therapeutic index or margin of safety.
Test your knowledge on drug therapeutics, including the main actions of drugs, effects on specific target organs, and potential side effects. Learn about how drugs can prevent, diagnose, and treat diseases, as well as their various effects on the human body.
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