Drug Solubility Quiz

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Questions and Answers

What is the primary reason for investigating approaches for solubility enhancement in pharmaceutical research?

  • To reduce the cost of drug production
  • To overcome limitations in a drug's biological application and pharmaceutical development (correct)
  • To simplify drug formulation processes
  • To increase the shelf life of drugs

When might solubility reduction be required in drug development?

  • For reducing the toxicity of drugs
  • For simplifying drug manufacturing processes
  • For increasing drug absorption
  • For sustained release products, taste masking, and enhancement of chemical stability (correct)

Why is knowledge of drug solubility important when direct administration into the bloodstream is desired?

  • To ensure the drug can be effectively administered (correct)
  • To reduce the risk of side effects
  • To enhance the drug's taste
  • To simplify the drug administration process

In what stage of drug development is a drug solution preferred for conducting studies?

<p>Pharmacological, toxicological, and pharmacokinetic studies (B)</p> Signup and view all the answers

How long has solubility enhancement been a regular element of pharmaceutical research?

<p>For several decades (D)</p> Signup and view all the answers

What is the primary factor affecting the bioavailability of an orally administered drug?

<p>Solubility in the gastrointestinal tract (B)</p> Signup and view all the answers

Why is it essential for drug molecules to be present in a dissolved form for transportation across biological membranes?

<p>To facilitate transport across biological membranes (A)</p> Signup and view all the answers

What can low aqueous solubility of a drug potentially do to its absorption?

<p>Delay or limit drug absorption (B)</p> Signup and view all the answers

What is the basis for the biopharmaceutical classification system (BCS)?

<p>Solubility and permeability of a drug (A)</p> Signup and view all the answers

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