Drug Interactions and Contraindications Quiz

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Questions and Answers

What is the most commonly used drug in a patient with chronic atrial fibrillation to prevent thromboembolism?

  • Oral direct thrombin inhibitors
  • Heparin
  • Aspirin
  • Warfarin (correct)

Which drug is recommended for unstable angina?

  • Heparin (correct)
  • Warfarin
  • Antiplatelet drugs
  • Oral inhibitors of factor Xa

In which condition are anticoagulants contraindicated due to an increased risk of bleeding?

  • Arterial circulation disorders
  • Venous thrombosis
  • Peptic ulcers (correct)
  • Oral direct thrombin inhibitors

Which type of drugs are effective in arterial circulation where anticoagulants have little effect?

<p>Antiplatelet drugs (D)</p> Signup and view all the answers

What is the primary mechanism of action of Cyclooxygenase-1 (COX-1) Inhibitors like Aspirin?

<p>Reduce thromboxane A2 synthesis (C)</p> Signup and view all the answers

What is a common contraindication for anticoagulant use?

<p>Tuberculosis (A)</p> Signup and view all the answers

What is a contraindication for the use of heparin and LMWH?

<p>Chronic alcoholism (C)</p> Signup and view all the answers

Which factor does Low Molecular Weight Heparins (LMWH) interfere with primarily?

<p>Factor Xa (C)</p> Signup and view all the answers

Which factor enhances the effect of warfarin?

<p>Debility (C)</p> Signup and view all the answers

Which drug is an oral direct thrombin inhibitor?

<p>Dabigatran (C)</p> Signup and view all the answers

Which factor is inhibited by oral inhibitors of factor Xa?

<p>Prothrombin (A)</p> Signup and view all the answers

What is a potential benefit of using LMWH compared to Heparin?

<p>Need for laboratory monitoring (A)</p> Signup and view all the answers

Which medication is commonly used for the prophylaxis of DVT and Pulmonary embolism?

<p>LMWH (B)</p> Signup and view all the answers

In which condition is the use of warfarin contraindicated?

<p>Gastrointestinal ulcer (D)</p> Signup and view all the answers

What is a contraindication for warfarin therapy?

<p>Pregnancy (D)</p> Signup and view all the answers

What are anticoagulants mainly used for?

<p>Venous thrombosis (B)</p> Signup and view all the answers

Which drug reduces the effect of warfarin?

<p>Rifampicin (D)</p> Signup and view all the answers

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