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Drug Interaction Quiz

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Questions and Answers

Which drug is a potent inhibitor of the cytochrome P450 isoenzyme CYP2D6?

Tramadol

Paroxetine (correct)

SSRIs

O-desmethyltramadol

What is the main mechanism of action for tramadol?

Reduction in seizure threshold

Inhibition of serotonin reuptake

Opioid effect mediated by O-desmethyltramadol (correct)

Inhibition of cytochrome P450 isoenzyme CYP2D6

What is the risk of taking tramadol and SSRIs together?

Unpredictable drug interactions

Reduced analgesia

Serotonin syndrome (correct)

Increased risk of seizures

How do SSRIs affect the seizure threshold?

<p>Reduce the seizure threshold</p> Signup and view all the answers

Drug Interaction Quiz

Choose a study mode

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Questions and Answers

Which drug is a potent inhibitor of the cytochrome P450 isoenzyme CYP2D6?

What is the main mechanism of action for tramadol?

What is the risk of taking tramadol and SSRIs together?

How do SSRIs affect the seizure threshold?

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