Drug-Induced Hematologic Disorders - PHAR 5367

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Which of the following is NOT listed as one of the most common drug-induced hematologic disorders?

Leukopenia

What was the first drug reported to be associated with agranulocytosis?

Sulfanilamide

Who is more susceptible to the hematologic effects of drugs according to the text?

Elderly people

Which drug-induced hematologic disorder is reported to be most common in the text?

<p>Thrombocytopenia</p> Signup and view all the answers

According to the text, what is the risk of death associated with drug-induced hematologic disorders and increasing age?

<p>Increases</p> Signup and view all the answers

Which of the following is NOT listed as a learning objective for the Integrated Hematology/Oncology Module - PHAR 5367?

<p>Identify all drugs that can lead to common hematologic disorders</p> Signup and view all the answers

Which of the following is a recommended method for confirming a diagnosis of drug-induced hematologic disorders?

<p>Conducting in vitro studies with the offending agent and patient’s blood</p> Signup and view all the answers

What is the leading cause of death associated with drug-induced hematologic disorders?

<p>Aplastic anemia</p> Signup and view all the answers

What is the approximate percentage of patients who receive heparin and develop heparin-induced thrombocytopenia (HIT)?

<p>5%</p> Signup and view all the answers

Which of the following is NOT a criterion for diagnosing drug-induced aplastic anemia?

<p>Platelet count of ≤ 100,000 cells/mm3</p> Signup and view all the answers

At what percentage of reticulocyte count is a hemoglobin level of ≤ 10 g/dL considered as one of the criteria for diagnosing drug-induced aplastic anemia?

<p>&lt;= 30,000 cells/mm3</p> Signup and view all the answers

What type of cells do progenitor cells differentiate into?

<p>All types of blood cells</p> Signup and view all the answers

Which of the following is characteristic of drug-induced aplastic anemia?

<p>Hypocellular bone marrow</p> Signup and view all the answers

What is the recommended approach regarding lab confirmation for interrupting/discontinuing therapy for drug-induced hematologic disorders?

<p>Lab confirmation is not necessary before interrupting therapy</p> Signup and view all the answers

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