Podcast
Questions and Answers
What is the primary concern about St. John's Wort with regard to medications?
What is the primary concern about St. John's Wort with regard to medications?
Which of the following medications is likely to be affected by St. John's Wort?
Which of the following medications is likely to be affected by St. John's Wort?
What is the mechanism by which St. John's Wort interacts with medications?
What is the mechanism by which St. John's Wort interacts with medications?
What is the potential consequence of taking St. John's Wort with certain medications?
What is the potential consequence of taking St. John's Wort with certain medications?
Signup and view all the answers
Why is it important to consult a healthcare professional before taking St. John's Wort?
Why is it important to consult a healthcare professional before taking St. John's Wort?
Signup and view all the answers
How should St. John's Wort be approached in terms of medication?
How should St. John's Wort be approached in terms of medication?
Signup and view all the answers
What is the implication of St. John's Wort being an active medication?
What is the implication of St. John's Wort being an active medication?
Signup and view all the answers
Why is it important to approach St. John's Wort with caution?
Why is it important to approach St. John's Wort with caution?
Signup and view all the answers
What does the classification of St. John's Wort as an active medication imply?
What does the classification of St. John's Wort as an active medication imply?
Signup and view all the answers
What is the significance of St. John's Wort being treated like prescribed pharmaceuticals?
What is the significance of St. John's Wort being treated like prescribed pharmaceuticals?
Signup and view all the answers
What is the effect of St. John's Wort on the efficacy of co-medications?
What is the effect of St. John's Wort on the efficacy of co-medications?
Signup and view all the answers
Which CYP450 isozymes are induced by St. John's Wort in a clinically relevant manner?
Which CYP450 isozymes are induced by St. John's Wort in a clinically relevant manner?
Signup and view all the answers
What type of interaction does St. John's Wort have with medications?
What type of interaction does St. John's Wort have with medications?
Signup and view all the answers
What is the effect of St. John's Wort on the metabolism of medications?
What is the effect of St. John's Wort on the metabolism of medications?
Signup and view all the answers
Which of the following is a consequence of St. John's Wort's effect on CYP450 isozymes?
Which of the following is a consequence of St. John's Wort's effect on CYP450 isozymes?
Signup and view all the answers
Study Notes
Drug-Herb Interactions
- St. John's wort is a potent inducer of CYP3A4 and CYP2B6, as well as many other CYP450 isozymes.
- This results in a clinically relevant reduction in the efficacy of co-medications due to pharmacokinetic interactions.
- St. John's wort is an active medication and should be treated with the same caution as prescribed pharmaceuticals.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Related Documents
Description
This quiz covers the pharmacokinetic interactions of St John's Wort, a potent inducer of CYP3A4 and CYP2B6, and its effects on co-medications. Test your knowledge of drug-herb interactions and their clinical relevance.
