Drug Formulation and Transdermal Delivery Quiz

Play an AI-generated podcast conversation about this lesson

What process causes air pockets in cells to expand and oscillate, disorganizing the lipid bilayers and forming channels through them?

Sonication (correct)

Vesiculation

Ionization

Osmosis

Which type of transdermal patch lacks a rate-limiting membrane?

Reservoir type with rate limiting membrane

Reservoir type without rate limiting membrane

Matrix type without rate limiting membrane (correct)

Matrix type with rate limiting membrane

Which penetration enhancer involves the use of micro-sized needles?

Sonication

Phonophoresis

Microneedles (correct)

Iontophoresis

What is the purpose of the drug-adhesive layer in a matrix-type transdermal patch?

Controlling drug release rate Signup and view all the answers

Which technique uses ultrasound to enhance percutaneous absorption?

Phonophoresis Signup and view all the answers

In iontophoresis, the drug molecule becomes:

Protonated Signup and view all the answers

Which of the following is a technique used to enhance percutaneous drug absorption?

All of the above Signup and view all the answers

How does iontophoresis enhance percutaneous drug absorption?

By applying an electrical current to drive ionized drugs across the skin Signup and view all the answers

What is the primary mechanism of action for microneedles in enhancing percutaneous drug absorption?

Creating microscopic channels in the stratum corneum Signup and view all the answers

Which of the following statements about phonophoresis is correct?

It uses low-frequency ultrasound waves to enhance drug absorption Signup and view all the answers

Which layer of the skin is primarily responsible for the barrier to drug permeation?

Stratum corneum Signup and view all the answers

Which of the following characteristics is desirable for a drug to be a good candidate for percutaneous absorption?

Both aqueous and lipid solubility Signup and view all the answers

Application of an electric field to enhance the penetration of ionic drug through skin membrane is called _______.

Iontophoresis Signup and view all the answers

In which type of transdermal transport, the drug molecule stays in the lipid bilayer and winds around the keratinocytes on its way to the dermis?

Intercellular diffusion Signup and view all the answers

Application of high frequency ultrasound to enhance the penetration of drug through skin membrane is called _______.

Sonophoresis Signup and view all the answers

In which type of TDDS, the drug is uniformly dispersed throughout the hydrophilic or lipophilic matrix?

Matrix type Signup and view all the answers

Which is a type of TDDS with a reservoir of scopolamine for the prevention of nausea?

Transderm Signup and view all the answers

Which of the following techniques can be used to enhance the percutaneous absorption of drugs?