Podcast
Questions and Answers
Which factor affects the distribution of drugs across the blood-brain barrier?
Which factor affects the distribution of drugs across the blood-brain barrier?
- Lipid and water solubility (correct)
- pH of maternal and fetal blood
- Plasma protein duration of action
- Plasma protein binding
Which drug can penetrate the blood-brain barrier rapidly to produce general anesthesia?
Which drug can penetrate the blood-brain barrier rapidly to produce general anesthesia?
- Tetracycline
- Dopamine
- Barbital
- Thiopental (correct)
What is the main plasma protein involved in drug binding with acidic drugs?
What is the main plasma protein involved in drug binding with acidic drugs?
- Dicoumarol
- Albumin (correct)
- Thiopental
- Globulin
Why can't dopamine be used as a replacement therapy for Parkinsonism?
Why can't dopamine be used as a replacement therapy for Parkinsonism?
Which factor affects placental distribution of drugs?
Which factor affects placental distribution of drugs?
Which of the following is NOT a physiological barrier to drug distribution?
Which of the following is NOT a physiological barrier to drug distribution?
What is the distribution equilibrium of mepacrine in the liver compared to plasma?
What is the distribution equilibrium of mepacrine in the liver compared to plasma?
What factor affects the cellular distribution of drugs according to the pH-partition theory?
What factor affects the cellular distribution of drugs according to the pH-partition theory?
Which type of tissue is classified as poorly perfused in drug distribution?
Which type of tissue is classified as poorly perfused in drug distribution?
In what condition is the cellular distribution of phenobarbital enhanced?
In what condition is the cellular distribution of phenobarbital enhanced?
