Podcast
Questions and Answers
What is the main goal of drug delivery and targeting?
What is the main goal of drug delivery and targeting?
Who introduced the concept of finding a selective target for drug delivery?
Who introduced the concept of finding a selective target for drug delivery?
What is the difference between conventional and non-conventional dosage forms?
What is the difference between conventional and non-conventional dosage forms?
What is the difference between first-order and second-order targeting?
What is the difference between first-order and second-order targeting?
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What are prodrugs?
What are prodrugs?
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What are monoclonal antibodies used for in drug delivery?
What are monoclonal antibodies used for in drug delivery?
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What are macromolecular carriers in drug delivery?
What are macromolecular carriers in drug delivery?
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Study Notes
Drug Delivery and Targeting Approaches
- Drug delivery and targeting aim to deliver drugs to their precise site of action at the right concentration and time.
- The drug needs to be pharmacologically active and arrive at the right place and time to exert its pharmaceutical effect.
- In cancer, there are minimal differences between cancer and non-cancer cells, while bacterial and mammalian cells have significant differences.
- Paul Ehrlich introduced the concept of finding a selective target, also known as the magic bullet.
- Drug targeting aims to localize and concentrate drugs to the desired therapeutic site while avoiding side effects.
- First-order targeting involves targeting an organ or tissue, second-order targeting targets a certain type of cells, and third-order targeting targets intracellular compartments.
- Conventional dosage forms rely on the physicochemical properties of the active ingredient, while non-conventional dosage forms rely on the technological characteristics of the formulation.
- Slow drug release leads to modified release formulations.
- Different drug delivery approaches include monoclonal antibodies, prodrugs, and macromolecular carriers.
- Monoclonal antibodies are potent and selective active pharmaceutical ingredients that bind to antigens.
- Prodrugs are chemically and pharmacologically inactive derivatives of the drug that are activated at the site of action.
- Macromolecular carriers transport the drug to the desired site of action and ensure selectivity, with carriers being either particulate or soluble.
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Description
Test your knowledge on drug delivery and targeting approaches with this informative quiz. Explore the concept of finding selective targets, different drug delivery approaches, and the different types of targeting. Learn about conventional and non-conventional dosage forms and slow drug release. This quiz will help you understand how drugs are delivered to their precise site of action and why drug targeting is essential for effective therapeutic outcomes.
