Donepezil Drug Interactions Quiz

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What is the primary interaction between donepezil and anticholinergic drugs?

Donepezil increases the bioavailability of anticholinergics.

Donepezil and anticholinergics do not interact with each other.

Donepezil antagonizes the activity of anticholinergics. (correct)

Donepezil and anticholinergics have a synergistic cholinergic effect.

Which of the following is the recommended action if bethanechol and donepezil must be given concurrently?

Increase the dose of bethanechol.

Increase the dose of donepezil.

Decrease the dose of bethanechol. (correct)

No dose adjustments are necessary.

How does donepezil affect the pharmacokinetics of furosemide, digoxin, and warfarin?

Donepezil increases the bioavailability of these drugs.

Donepezil decreases the binding of these drugs.

Donepezil increases the binding of these drugs.

Donepezil does not affect the binding of these drugs. (correct)

What is the recommended action when donepezil is co-administered with CYP2D6 and 3A4 inducers?

Avoid concurrent administration. Signup and view all the answers

How does cimetidine affect the pharmacokinetics of galantamine?

Cimetidine increases the bioavailability of galantamine by 16%. Signup and view all the answers

What is the recommended action when memantine is co-administered with drugs that make the urine alkaline?

Avoid concurrent administration or monitor for increased drug effects. Signup and view all the answers

Which of the following drugs should be avoided when using neostigmine or pyridostigmine?

All of the above Signup and view all the answers

What is the concern with using corticosteroids concurrently with neostigmine or pyridostigmine?

Corticosteroids decrease the anti-AChE effects of neostigmine or pyridostigmine Signup and view all the answers

Which of the following statements about magnesium is correct?

Magnesium has a direct depressant effect on skeletal muscle and may antagonize the beneficial effects of neostigmine or pyridostigmine Signup and view all the answers

What is the potential concern with using methocarbamol concurrently with pyridostigmine?

The concern is based on a single case report, and more information is needed Signup and view all the answers

Which of the following statements about rivastigmine is correct?

Both B and C Signup and view all the answers

What is the concern with using local and general anesthetics or antiarrhythmics concurrently with neostigmine?

These drugs may decrease the effects of neostigmine Signup and view all the answers

Donepezil Drug Interactions Quiz

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Questions and Answers

What is the primary interaction between donepezil and anticholinergic drugs?

Which of the following is the recommended action if bethanechol and donepezil must be given concurrently?

How does donepezil affect the pharmacokinetics of furosemide, digoxin, and warfarin?

What is the recommended action when donepezil is co-administered with CYP2D6 and 3A4 inducers?

How does cimetidine affect the pharmacokinetics of galantamine?

What is the recommended action when memantine is co-administered with drugs that make the urine alkaline?

Which of the following drugs should be avoided when using neostigmine or pyridostigmine?

What is the concern with using corticosteroids concurrently with neostigmine or pyridostigmine?

Which of the following statements about magnesium is correct?

What is the potential concern with using methocarbamol concurrently with pyridostigmine?

Which of the following statements about rivastigmine is correct?

What is the concern with using local and general anesthetics or antiarrhythmics concurrently with neostigmine?

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