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Questions and Answers
How does gemcitabine inhibit DNA synthesis?
How does gemcitabine inhibit DNA synthesis?
- By cross-linking DNA strands
- By alkylating DNA
- By inhibiting DNA synthesis specifically during the S-phase (correct)
- By forming intrastrand bonds with DNA bases
Which drug cross-links DNA by forming intrastrand and interstrand covalent bonds?
Which drug cross-links DNA by forming intrastrand and interstrand covalent bonds?
- Cisplatin (correct)
- Bleomycin
- Doxorubicin
- Mitomycin C
What is the mechanism of action of Vinblastine?
What is the mechanism of action of Vinblastine?
- Inhibits topoisomerase II
- Inhibits mitosis by blocking microtubule assembly (correct)
- Inhibits DNA synthesis during the S-phase
- Cross-links DNA strands
How does Etoposide affect DNA?
How does Etoposide affect DNA?
Which drug inhibits the BRAF gene to prevent tumour proliferation?
Which drug inhibits the BRAF gene to prevent tumour proliferation?
What is the target of Bevacizumab when used as a monoclonal antibody?
What is the target of Bevacizumab when used as a monoclonal antibody?
How does Pemetrexed inhibit DNA synthesis?
How does Pemetrexed inhibit DNA synthesis?
How does Mercaptopurine interfere with DNA synthesis?
How does Mercaptopurine interfere with DNA synthesis?
What is the mechanism of action of Fludarabine and Cladribine in disrupting DNA synthesis?
What is the mechanism of action of Fludarabine and Cladribine in disrupting DNA synthesis?
How does Cytarabine block DNA synthesis?
How does Cytarabine block DNA synthesis?
What is the impact of Fluorouracil on DNA and RNA synthesis?
What is the impact of Fluorouracil on DNA and RNA synthesis?
What is the primary effect of Thioguanine on DNA synthesis?
What is the primary effect of Thioguanine on DNA synthesis?
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