DNA Structure Flashcards

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Questions and Answers

The correct structure of DNA components can be presented as:

  • Base-sugar-phosphate-base
  • Phosphate-base-sugar
  • Base-phosphate-sugar
  • Phosphate-sugar-base (correct)
  • Phosphate-sugar-phosphate-base

Which of the following is a characteristic of double-stranded DNA?

  • 2 nanometers in width
  • A and B
  • 0.34 nanometers per base pair
  • 10 base pairs per turn
  • A, B and C (correct)

Which of the following DNA molecules is the most stable?

  • AGTCGAAT TCAGCTTA
  • GCGTGCAC CGCACGTG (correct)
  • CTGCATAC GACGTATG
  • GGATCCTG CCTAGGAC
  • GAAATTTC CTTTAAAG

Doubled-stranded DNA consists of two antiparallel strands, meaning that one strand is oriented in the 5' to 3' direction, while the other is oriented in the 3' to 5' direction.

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Asymmetrical spacing of the backbones of the DNA double helix generates major and minor grooves.

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Study Notes

DNA Structure Fundamentals

  • DNA components are structured in the order phosphate-sugar-base, which is critical for its formation and function.
  • The correct sequencing of components impacts the overall properties and stability of DNA.

Characteristics of Double-Stranded DNA

  • Double-stranded DNA has a consistent width of 2 nanometers.
  • The helix structure features 10 base pairs per turn, contributing to its stability.
  • Each base pair measures 0.34 nanometers, which is essential for the consistent structure of the helix.

Stability of DNA Molecules

  • Among the provided DNA molecules, the GCGTGCAC/CACGTGC sequence is the most stable due to its composition and pairing.
  • Stability can depend on base pair interactions, influencing DNA's structural integrity.

Antiparallel Strands

  • DNA consists of two antiparallel strands; one runs in the 5' to 3' direction while the other runs in the 3' to 5' direction, essential for replication and transcription processes.

Groove Formation in DNA

  • The asymmetrical arrangement of the DNA double helix backbones gives rise to major and minor grooves, which play crucial roles in protein binding and interactions with other molecules.

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