Molecular Biology: DNA Structure and Replication
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Questions and Answers

What happens to telomeres in humans with each cell division throughout life?

  • They increase in length
  • They shorten in length (correct)
  • They remain constant in length
  • They disappear completely

    • What is responsible for the maintenance of telomeres in humans?

  • hTERT only
  • Neither hTERT nor hTR
  • hTR only
  • Both hTERT and hTR (correct)

    • What is the result of telomere shortening in somatic cells?

  • Replicative senescence (correct)
  • Apoptosis
  • Cell proliferation
  • Cancer

    • What is the role of senescent cells in ageing?

    <p>They accelerate ageing</p> Signup and view all the answers

    What is the consequence of ectopic activation of telomerase in humans?

    <p>Cancer</p> Signup and view all the answers

    What is the characteristic of telomeres in Werner syndrome (WS) cells?

    <p>They are shorter than normal</p> Signup and view all the answers

    What is the function of hTR in telomere maintenance?

    <p>It acts as a template RNA</p> Signup and view all the answers

    What is the effect of telomere shortening on cellular replication?

    <p>It stops cell replication</p> Signup and view all the answers

    What is the relationship between telomere length and cellular lifespan?

    <p>Telomere length is directly proportional to cellular lifespan</p> Signup and view all the answers

    What is the consequence of compromising D loop integrity?

    <p>Irreversible exit from the cell cycle</p> Signup and view all the answers

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