Podcast
Questions and Answers
What was a significant source of evidence for Watson and Crick's model of DNA?
What was a significant source of evidence for Watson and Crick's model of DNA?
What is the primary role of the sugar-phosphate backbone in the DNA structure?
What is the primary role of the sugar-phosphate backbone in the DNA structure?
Which base pairing is correct according to Chargaff's Rule?
Which base pairing is correct according to Chargaff's Rule?
Which of the following best describes the relationship between Rosalind Franklin and the Nobel Prize awarded to Watson and Crick?
Which of the following best describes the relationship between Rosalind Franklin and the Nobel Prize awarded to Watson and Crick?
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What method did Crick and Watson use to create their famous model of DNA?
What method did Crick and Watson use to create their famous model of DNA?
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Study Notes
DNA Structure
- DNA is a double helix, resembling a twisted ladder.
- The uprights of the ladder are made of a sugar-phosphate backbone.
- The rungs of the ladder are composed of paired bases.
- Adenine (A) always pairs with Thymine (T).
- Guanine (G) always pairs with Cytosine (C).
- This pairing is always in equal ratios (Chargaff's Rule).
- The sequence of bases forms the genetic code.
- When DNA unzips, each half attracts new complementary bases.
- This creates two identical DNA molecules.
DNA Discovery
- In 1953, Francis Crick and James Watson proposed a model of DNA.
- Rosalind Franklin's X-ray diffraction image of DNA was crucial to their discovery.
- Watson and Crick published a landmark paper about their DNA model in April 1953.
- Franklin's contributions were not fully recognized until later.
Nobel Prize
- In 1962, Watson, Crick, and Maurice Wilkins won the Nobel Prize in Physiology or Medicine for their work on DNA.
- Wilkins was part of Franklin's research team, but she passed away before the prize was awarded.
3-D Model
- Crick and Watson created a famous 3-D model of DNA using various materials.
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Description
Test your knowledge on the structure and discovery of DNA. This quiz covers key elements such as the double helix model, base pairing rules, and significant contributions by scientists like Watson, Crick, and Franklin. Challenge yourself to remember the details about DNA's genetic code and its historical significance.