Podcast
Questions and Answers
What specific contribution did Rosalind Franklin make to the discovery of the DNA double helix structure?
What specific contribution did Rosalind Franklin make to the discovery of the DNA double helix structure?
Which base pair rule, crucial for DNA structure, did Watson and Crick utilize?
Which base pair rule, crucial for DNA structure, did Watson and Crick utilize?
What does the order of bases in a DNA strand represent?
What does the order of bases in a DNA strand represent?
Which technique did Rosalind Franklin use to provide evidence for the double helix?
Which technique did Rosalind Franklin use to provide evidence for the double helix?
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Which event occurred first in the historical timeline of the DNA structure discovery?
Which event occurred first in the historical timeline of the DNA structure discovery?
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Why was Rosalind Franklin's contribution to the DNA structure discovery not recognized at the time as it should have been?
Why was Rosalind Franklin's contribution to the DNA structure discovery not recognized at the time as it should have been?
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What comparison is used to describe the structure of the DNA double helix?
What comparison is used to describe the structure of the DNA double helix?
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Which of the following did NOT participate in the discovery of DNA's structure?
Which of the following did NOT participate in the discovery of DNA's structure?
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During DNA replication, what happens to the DNA ladder?
During DNA replication, what happens to the DNA ladder?
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What materials did Watson and Crick use to create their 3D model of DNA?
What materials did Watson and Crick use to create their 3D model of DNA?
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Flashcards
DNA Double Helix
DNA Double Helix
The twisted ladder structure of DNA, consisting of two strands.
Rosalind Franklin
Rosalind Franklin
The scientist who produced the famous Photograph 51 of DNA.
Chargaff's Rule
Chargaff's Rule
The observation that A pairs with T and C pairs with G in DNA.
Watson and Crick Model
Watson and Crick Model
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DNA Replication
DNA Replication
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Photograph 51
Photograph 51
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Nobel Prize in Physiology or Medicine
Nobel Prize in Physiology or Medicine
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Landmark Paper
Landmark Paper
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Gene
Gene
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Base Pairing
Base Pairing
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Study Notes
DNA Structure and Discovery
- DNA structure resembles a twisted ladder, with the phosphate and sugar molecules forming the uprights and the paired bases forming the rungs.
- Franklin's X-ray diffraction image (Photograph 51) revealed DNA's double helix structure, crucial for Watson and Crick's model.
- Watson and Crick determined that the bases (A, T, C, and G) pair consistently (A with T, and C with G). This base-pairing principle dictates the genetic code.
- The sequence of bases is the key to genetic information.
- When DNA replicates, the "ladder splits in half," each half-ladder bonds with new components to create two identical DNA molecules.
- In March 1953, Watson and Crick completed and published their model.
- Franklin's contribution wasn't fully recognized until after her death in 1958.
- Watson, Crick, and Wilkins jointly won the Nobel Prize in 1962 for their discovery.
- The discovery marked a pivotal moment in understanding genetics and triggered advancements in molecular biology.
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Description
Explore the groundbreaking discoveries surrounding the structure of DNA, from its twisted ladder appearance to the pivotal contributions of scientists like Watson, Crick, and Franklin. Learn about the base pairing rules that dictate genetic information and the significance of the double helix model in the history of genetics.
