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Questions and Answers
What defines the 5' end of a DNA strand?
What defines the 5' end of a DNA strand?
What component primarily forms the backbone of DNA's primary structure?
What component primarily forms the backbone of DNA's primary structure?
Which statement accurately describes the structure of DNA?
Which statement accurately describes the structure of DNA?
Which unit is not a component of the monomeric units in DNA strands?
Which unit is not a component of the monomeric units in DNA strands?
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What characteristic of deoxyribose subunits and phosphate groups is highlighted in DNA's structure?
What characteristic of deoxyribose subunits and phosphate groups is highlighted in DNA's structure?
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Which feature of DNA's secondary structure pertains to base arrangement?
Which feature of DNA's secondary structure pertains to base arrangement?
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Study Notes
The 5' and 3' Ends
- The 5' end features a free phosphate group, indicating an unlinked position in the phosphodiester bond.
- The 3' end is identified by a free hydroxyl group or phosphate group.
The Primary Structure of DNA
- Primary structure focuses on the sequence and quantity of deoxyribonucleotides in DNA strands, linked through phosphodiester bonds.
- The backbone consists of a linear arrangement of sugar-phosphate groups, with nitrogenous bases (purines or pyrimidines) extending from the sugar, creating a lateral projection.
The Double Helix
- DNA consists of two complementary strands of polydeoxyribonucleotides with opposing polarity, forming a right-handed helical shape.
- Each strand is made up of monomeric units known as deoxynucleoside 5'-monophosphates, including dAMP (deoxyadenylate), dGMP (deoxyguanylate), dTMP (deoxythymidine), and dCMP (deoxycytidine).
- The exterior of the double helix contains hydrophilic deoxyribose sugar and phosphate, interacting with the surrounding aqueous environment, while the hydrophobic interior holds the stacked planar bases.
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Description
Learn about the 5' and 3' ends of a DNA strand, including the phosphate groups and hydroxyl groups that define them, as well as the primary structure of DNA.