DNA, RNA, Replication and Protein Synthesis
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Questions and Answers

Explain how semi-conservative replication ensures genetic continuity during cell division, and what would be the consequence if replication was fully conservative?

Semi-conservative replication results in two DNA molecules, each with one original and one new strand, preserving genetic information. If replication was fully conservative, with one original and one entirely new DNA molecule, any replication errors that occurred in the new strand would not have the original strand available as a template potentially leading to a higher accumulation of mutations.

A scientist introduces a mutation into a gene that codes for a tRNA molecule. How might this mutation affect the process of translation and protein synthesis?

A mutation in tRNA can affect its ability to recognize the correct mRNA codon or carry the appropriate amino acid. This can cause incorrect amino acid incorporation, premature termination, or a non-functional protein disrupting protein synthesis.

In a species of flowering plants, the allele $R$ for red flowers is incompletely dominant over the allele $W$ for white flowers. Heterozygous ($RW$) plants have pink flowers. If a pink-flowered plant is crossed with a white-flowered plant, what is the probability that the offspring will have red flowers? Explain your reasoning.

Since red ($RR$) is incompletely dominant over white ($WW$), the heterozygous offspring ($RW$) will have pink flowers. Thus, crossing a pink-flowered plant ($RW$) with a white-flowered plant ($WW$) will result in a 0% probability of producing red ($RR$) flowered offspring.

Describe the roles of mRNA, tRNA, and rRNA in the process of protein synthesis, highlighting how their functions are interconnected to ensure accurate translation of the genetic code.

<p>mRNA carries the genetic code from DNA to the ribosome. tRNA brings specific amino acids to the ribosome, matching its anticodon to the mRNA codon. rRNA forms the ribosome, which catalyzes peptide bond formation between amino acids. Together, they ensure accurate and efficient translation.</p> Signup and view all the answers

Explain how external environmental factors such as radiation exposure can lead to mutations in DNA, and what are the potential consequences of these mutations at the cellular and organismal levels?

<p>Radiation can cause DNA damage, leading to mutations like base changes, deletions, or insertions. At the cellular level, this can result in cell death or uncontrolled growth (cancer). At the organismal level, mutations can cause genetic disorders or evolutionary changes.</p> Signup and view all the answers

Flashcards

Double Helix

The structure of DNA, resembling a twisted ladder with two strands.

Codon

A sequence of three nucleotides that encodes a specific amino acid.

Punnett Square

A diagram used to predict the genotype and phenotype ratios of offspring from a genetic cross.

Semi-Conservative Replication

The process of DNA replication where each new DNA molecule consists of one old strand and one new strand.

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Mendelian Inheritance

A type of inheritance described by Gregor Mendel, involving dominant and recessive traits.

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Study Notes

Key Vocabulary

  • DNA/RNA: Deoxyribonucleic Acid/Ribonucleic Acid
  • Double Helix: The structure of DNA, resembling a twisted ladder
  • Nucleotides: The building blocks of DNA and RNA
  • Chargaff's Rules of Base Pairing: Specific pairing rules for DNA bases (A with T, C with G)
  • Codon/Anticodon: Codons are three-base sequences on mRNA, while anticodons are on tRNA
  • Replication: The process of copying DNA
  • Semi-Conservative Replication: The method of DNA replication, where each new DNA molecule contains one strand from the original molecule and one newly synthesized strand.
  • Mutation: A change in the DNA sequence
  • RNA (mRNA, tRNA, rRNA): Ribonucleic Acid; mRNA carries genetic information from DNA to ribosomes; tRNA carries amino acids to ribosomes; rRNA is a component of ribosomes.
  • Transcription: The process of making RNA from DNA
  • Translation: The process of making proteins from RNA
  • Gamete: Sex cells (sperm and egg)
  • Punnett Square: A grid used to predict the genotypes and phenotypes of offspring from parents with known genotypes
  • Test Cross: A cross between an organism with an unknown genotype and an organism with a known homozygous recessive genotype
  • Karyotype: A visual representation of an organism's chromosomes
  • Genotype/Phenotype: Genotype is the genetic makeup, while phenotype is the observable traits
  • Homozygous/Heterozygous: Homozygous has two identical alleles, while heterozygous has two different alleles
  • Dominant/Recessive: Dominant traits are expressed even if only one copy of the allele is present; recessive traits are only expressed if two copies of the allele are present
  • Carrier: An individual with one copy of a recessive allele but doesn't express the trait
  • Allele: Different forms of a gene
  • Gene: A segment of DNA that codes for a specific trait
  • DNA Fingerprinting: A technique used to identify individuals based on their unique DNA patterns
  • Inheritance Patterns:
  • Simple Mendelian Inheritance: Traits determined by a single gene with two alleles
  • Incomplete Dominance: Neither allele is completely dominant, resulting in an intermediate phenotype
  • Codominance: Both alleles are fully expressed in the phenotype, without blending
  • Polygenic Inheritance: Multiple genes influence a single trait
  • Sex-Linked Inheritance: Traits linked to sex chromosomes
  • Multiple Alleles: More than two alleles exist for a gene
  • Environmental Influences: Factors that affect gene expression (internal or external).

Key Skills/Ideas

  • Structure of DNA: Understand the structure of DNA, including nucleotides, base pairs, and bonds
  • DNA vs. RNA: Compare and contrast the structures, types and purposes of DNA and RNA.
  • Codon Chart: Use a codon chart to identify amino acids from mRNA codons. Do not attempt to memorize it.
  • Punnett Squares: Create and analyze Punnett Squares, including calculating phenotypic and genotypic ratios
  • Replication, Transcription, Translation: Understand the processes and relationship between them. Identify enzymes involved and location.
  • Inheritance Patterns: Identify and explain different patterns of inheritance. Be able to predict genotypes and phenotypes
  • Scientists: Know the scientists involved in the discovery and development of genetic concepts. Be able to link their discoveries to their work (e.g., Chargaff and the base pairing rules).

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Test your knowledge of key concepts related to DNA, RNA, replication, and protein synthesis. Topics include: DNA structure, base pairing rules, the roles of mRNA, tRNA, and rRNA, transcription, and translation. Perfect for high school biology and introductory college courses.

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