30 Questions
What characteristic is typically seen in the ulcer of a rodent ulcer?
Eroded edge
In basal cell carcinoma, how are the basal cells arranged in the dermis?
In a palisade manner
Which benign tumor is composed of fibrous tissue?
Fibroma
What differentiates carcinoma in situ from invasive carcinoma?
Intact basement membrane
Which tumor arises from smooth muscle cells?
Leiomyoma
What is the typical presentation of a fibroma?
Fibrous tissue growth
Which type of mutation is most commonly associated with cancer?
Somatic mutations
What percentage of all cancers are caused by germline mutations?
5%
Which type of genes are responsible for monitoring the rate of cell division and controlling apoptosis?
Tumor suppressor genes
What are recessive mutations in tumor suppressor genes associated with?
Induction of cancer
Which type of mutations are present normally as proto-oncogenes and are involved in cell growth?
Oncogene mutations
What protective events occur after DNA damage?
Arrest of cell division, activation of DNA repair enzymes or induction of apoptosis
Which type of papilloma is considered precancerous?
Columnar cell papilloma
Which gland is most commonly affected by a pituitary adenoma?
Pituitary
Which tumor arises from the mucosa of the GIT and gall bladder?
Adenomatous polyp
Which malignant tumor causes transmural growth and narrowing?
Infiltrating carcinoma
Which benign tumor arises from the secretory or glandular epithelium?
Adenoma
Which type of tumor is formed of differentiated cells as the original gland and is capsulated?
Adenoma
What is the primary function of tumor angiogenesis?
To provide a source of blood supply for the tumor
What is the role of vascular endothelial growth factor (VEGF) in tumor angiogenesis?
It induces capillary growth
Which of the following is not a characteristic of cancer stem cells?
They are a major population in tumor cells
Which of the following is a benign tumor arising from surface epithelium?
Papilloma
What is the primary cause of tumor angiogenesis?
Secretion of vascular endothelial growth factor (VEGF)
What is the significance of cancer stem cells in tumor therapy?
They are a major target for specific therapies
What type of tumor is a teratoma?
Benign tumor composed of mature tissue representing at least 2 embryonic layers
What is the origin of teratomas?
From pluripotent stem cells as germ cells and embryonal cells
Which of the following is a type of sarcoma?
Liposarcoma
What type of tumor is a nevus?
Benign tumor of pigmented cells
What is a hamartoma?
Focal malformation that consists of the same tissue elements normally found at that site but they are growing in a disorganized manner
What is a para-neoplastic syndrome?
Disorders that result from substances produced by the tumor (hormones or cytokines)
Test your knowledge on protective events following DNA damage, gene mutations, and the link between DNA damage and cancer. Learn about the consequences of unrepaired DNA damage and acquired gene mutations.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
