DNA Hydroxylation and Methylation Quiz
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Questions and Answers

Which process results in heritable expression or repression of genes?

  • Oxidative DNA adducts
  • DNA hydroxylation
  • DNA methylation (correct)
  • Oxidative DNA damage

What is the main source of oxidative DNA damage?

  • Excessive sunlight exposure
  • Air pollution
  • Free radical reactions in the cell (correct)
  • Chemicals in processed foods

Which type of DNA modification involves the transfer of a methyl group?

  • DNA hydroxylation
  • Oxidative DNA damage
  • DNA methylation (correct)
  • Oxidative DNA adducts

What is the role of S-adenosylmethionine in DNA modification?

<p>Donates a methyl group for DNA methylation (A)</p> Signup and view all the answers

What is a common feature of oxidative DNA adducts?

<p>Identified in all four DNA bases (A)</p> Signup and view all the answers

What is a characteristic of nongenotoxic carcinogens?

<p>They induce tumors in rodent models without causing DNA damage (B)</p> Signup and view all the answers

Which mode of action is NOT associated with nongenotoxic carcinogens?

<p>Direct DNA binding (B)</p> Signup and view all the answers

What is one of the mechanisms through which nongenotoxic carcinogens can induce tumors?

<p>Oxidative stress induction (C)</p> Signup and view all the answers

Which of the following is a mode of action of nongenotoxic carcinogens?

<p>a2u-Globulin binding (C)</p> Signup and view all the answers

Why do nongenotoxic carcinogens typically require prolonged exposure to produce tumors?

<p>To enable indirect mechanisms like altered methylation (C)</p> Signup and view all the answers

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