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DNA Hydroxylation and Methylation Quiz

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Questions and Answers

Which process results in heritable expression or repression of genes?

Oxidative DNA adducts

DNA hydroxylation

DNA methylation (correct)

Oxidative DNA damage

What is the main source of oxidative DNA damage?

Excessive sunlight exposure

Air pollution

Free radical reactions in the cell (correct)

Chemicals in processed foods

Which type of DNA modification involves the transfer of a methyl group?

DNA hydroxylation

Oxidative DNA damage

DNA methylation (correct)

Oxidative DNA adducts

What is the role of S-adenosylmethionine in DNA modification?

Donates a methyl group for DNA methylation Signup and view all the answers

What is a common feature of oxidative DNA adducts?

Identified in all four DNA bases Signup and view all the answers

What is a characteristic of nongenotoxic carcinogens?

They induce tumors in rodent models without causing DNA damage Signup and view all the answers

Which mode of action is NOT associated with nongenotoxic carcinogens?

Direct DNA binding Signup and view all the answers

What is one of the mechanisms through which nongenotoxic carcinogens can induce tumors?

Oxidative stress induction Signup and view all the answers

Which of the following is a mode of action of nongenotoxic carcinogens?

a2u-Globulin binding Signup and view all the answers

Why do nongenotoxic carcinogens typically require prolonged exposure to produce tumors?

To enable indirect mechanisms like altered methylation Signup and view all the answers