Lecture 3

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What are the two types of nucleic acids?

  • DNA and RNA (correct)
  • DNA and protein
  • RNA and lipid
  • RNA and protein

What is the sugar molecule found in DNA?

  • Deoxyribose (correct)
  • Fructose
  • Glucose
  • Ribose

Where is DNA mainly found in a cell?

  • Cytoplasm
  • Mitochondria
  • Ribosome
  • Nucleus (correct)

What is the function of hydrogen bonds in DNA?

<p>To hold the two strands of DNA together (A)</p> Signup and view all the answers

What is the difference between DNA and RNA in terms of pyrimidine bases?

<p>DNA has thymine, RNA has uracil (D)</p> Signup and view all the answers

What is the orientation of the two strands in a DNA molecule?

<p>The 5' end of one strand is opposite the 3' end of the other (A)</p> Signup and view all the answers

What is the structure of a DNA molecule?

<p>A double helix with two polynucleotide strands (C)</p> Signup and view all the answers

What is the number of chromosomes found in human somatic cells?

<p>23 pairs (46 individual) of chromosomes (B)</p> Signup and view all the answers

What is the primary function of histone proteins in DNA folding?

<p>To coil DNA into chromosomes (D)</p> Signup and view all the answers

What is the approximate number of base pairs in nuclear DNA?

<p>3 × 10^9 base pairs (A)</p> Signup and view all the answers

What is the term for having multiple copies of DNA in a mitochondrion?

<p>Polyploid (A)</p> Signup and view all the answers

What is the approximate percentage of the genome that codes for genes?

<p>2% (B)</p> Signup and view all the answers

What is the shape of mitochondrial DNA?

<p>Circular (A)</p> Signup and view all the answers

How many genes are found in mitochondrial DNA?

<p>37 genes (B)</p> Signup and view all the answers

What is the primary component of a nucleotide?

<p>A sugar molecule and a phosphate group (C)</p> Signup and view all the answers

Where is RNA primarily found in a cell?

<p>In the cytoplasm and nucleus (B)</p> Signup and view all the answers

What is the difference between the sugar molecules in DNA and RNA?

<p>DNA has deoxyribose, RNA has ribose (B)</p> Signup and view all the answers

What is the nitrogenous base found in RNA but not in DNA?

<p>Uracil (A)</p> Signup and view all the answers

How are the two strands of DNA held together?

<p>By hydrogen bonds between the nitrogenous bases (A)</p> Signup and view all the answers

What is the term for the packaged form of DNA in the nucleus?

<p>Chromosome (A)</p> Signup and view all the answers

What is the term for the components of a nucleotide?

<p>Nucleoside (B)</p> Signup and view all the answers

What is the primary distinction between nuclear DNA and mitochondrial DNA?

<p>Location within the cell (C)</p> Signup and view all the answers

What is the characteristic of chromosomes in human germline cells?

<p>They have 23 individual chromosomes (D)</p> Signup and view all the answers

What is the function of other proteins involved in DNA folding?

<p>To assist histone proteins in DNA folding (C)</p> Signup and view all the answers

What percentage of the genome is comprised of non-coding regions?

<p>98% (A)</p> Signup and view all the answers

What is the characteristic of nuclear DNA in human somatic cells?

<p>It is diploid (A)</p> Signup and view all the answers

What is the purpose of DNA coiling and folding?

<p>To form the structure of chromosomes (D)</p> Signup and view all the answers

What is the total number of base pairs found in mitochondrial DNA?

<p>16,000 (A)</p> Signup and view all the answers

What is the primary function of hydrogen bonds in a DNA molecule?

<p>To hold the two strands together (A)</p> Signup and view all the answers

Which of the following is NOT a characteristic of RNA?

<p>Contains the base thymine (D)</p> Signup and view all the answers

What is the orientation of the two strands in a DNA molecule?

<p>Opposite orientation (D)</p> Signup and view all the answers

What is the function of the sugar molecule in a nucleotide?

<p>To provide structural support to the nitrogenous base (B)</p> Signup and view all the answers

Where is DNA mainly packaged in a cell?

<p>Nucleus (A)</p> Signup and view all the answers

What is the main function of histone proteins in the process of DNA folding?

<p>To provide a framework for DNA coiling (B)</p> Signup and view all the answers

What is the characteristic of nuclear DNA in terms of its ploidy?

<p>Diploid (C)</p> Signup and view all the answers

What is the approximate number of genes found in mitochondrial DNA?

<p>37 (A)</p> Signup and view all the answers

What is the structure of mitochondrial DNA?

<p>Circular (A)</p> Signup and view all the answers

How many pairs of chromosomes are found in human somatic cells?

<p>46 (D)</p> Signup and view all the answers

What determines the regulation of gene expression in different cell types?

<p>The type of transcription factors present (A)</p> Signup and view all the answers

What is the primary function of transcription factors?

<p>To regulate gene expression (B)</p> Signup and view all the answers

What is the term for proteins that initiate or regulate transcription?

<p>Transcription factors (C)</p> Signup and view all the answers

At which stages can gene expression be regulated?

<p>Transcription, translation, and protein degradation (D)</p> Signup and view all the answers

What is the function of Gene A in the given scenario?

<p>To regulate gene expression in nerve cells (C)</p> Signup and view all the answers

What is the function of Gene D in the given scenario?

<p>To regulate gene expression in different cell types (C)</p> Signup and view all the answers

What is the role of chromatin structure in gene expression?

<p>To regulate transcription (B)</p> Signup and view all the answers

What is the characteristic of interspersed repeats in the genome?

<p>They are scattered in the genome with varying lengths. (C)</p> Signup and view all the answers

What is the term for DNA elements that consist of a repeat unit that runs in tandem and cluster together in the genome?

<p>Tandem repeats (B)</p> Signup and view all the answers

What is the function of microsatellites in forensic science?

<p>For paternity and forensic tests (C)</p> Signup and view all the answers

What is the term for genes that are expressed in all cells and are necessary for cellular processes such as transcription and metabolism?

<p>Housekeeping genes (C)</p> Signup and view all the answers

What is the term for genes that are expressed only in specific cell types, such as hemoglobin in red blood cells?

<p>Cell-type-specific genes (C)</p> Signup and view all the answers

What is the characteristic of gene expression in different cells?

<p>Different genes are expressed at different levels in different cells. (C)</p> Signup and view all the answers

What is the characteristic of the genetic material in all cells of the body?

<p>The same genetic material is found in all cells. (A)</p> Signup and view all the answers

What is the primary function of the DNA Binding Domain (DBD) in a transcription factor?

<p>To recognize specific DNA sequences (A)</p> Signup and view all the answers

What is the function of a silencer in regulating gene expression?

<p>To inhibit transcription by binding to a specific DNA sequence (A)</p> Signup and view all the answers

What is the typical location of a promoter in relation to a gene?

<p>Upstream of the gene, near the TSS (D)</p> Signup and view all the answers

What is the role of an enhancer in regulating gene expression?

<p>To enhance transcription by binding to a specific DNA sequence (C)</p> Signup and view all the answers

What is the function of a promoter in regulating gene expression?

<p>To determine the site of transcription initiation of a gene (D)</p> Signup and view all the answers

What is the primary difference between an enhancer and a silencer?

<p>Their function in regulating gene expression (A)</p> Signup and view all the answers

What is the role of a transcription factor in regulating gene expression?

<p>To recognize specific DNA sequences and promote or inhibit transcription (D)</p> Signup and view all the answers

What happens when a transcription factor binds to an enhancer?

<p>It recruits proteins necessary for transcription initiation. (A)</p> Signup and view all the answers

What is the result of a mutation in the WT1 gene?

<p>Kidney tumors develop in young children. (D)</p> Signup and view all the answers

What is the effect of a breakpoint 125kb downstream of the PAX6 gene?

<p>A deletion of regulatory elements essential for PAX6 expression. (C)</p> Signup and view all the answers

Why is chromatin structure important for gene expression?

<p>It prevents accessibility to DNA, making gene expression impossible. (D)</p> Signup and view all the answers

What is the function of a repressor transcription factor?

<p>It prevents the recruitment of proteins necessary for transcription. (A)</p> Signup and view all the answers

What is the consequence of a defect in a repressor?

<p>Abnormal conditions, such as Wilms' tumor, can occur. (B)</p> Signup and view all the answers

What is the role of an enhancer?

<p>It recruits proteins necessary for transcription initiation. (B)</p> Signup and view all the answers

What is the effect of a silencer?

<p>It prevents the recruitment of proteins necessary for transcription. (A)</p> Signup and view all the answers

What is the consequence of a mutation in the PAX6 gene?

<p>Aniridia occurs. (D)</p> Signup and view all the answers

Flashcards are hidden until you start studying

More Like This

Use Quizgecko on...
Browser
Browser