Diverticulosis Overview
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Questions and Answers

What is the most pathogenic component of gluten?

  • MHC class II
  • tTG
  • IgA antibodies
  • Gliadin (correct)

Which cells mediate tissue damage in individuals with celiac disease?

  • Antigen presenting cells
  • Helper T cells (correct)
  • B cells
  • Natural killer cells

What is the classic presentation of celiac disease in adults?

  • Chronic diarrhea and bloating (correct)
  • Abdominal distension and failure to thrive
  • Increased intraepithelial lymphocytes
  • Skin vesicles (dermatitis herpetiformis)

What do IgA antibodies against in celiac disease?

<p>Endomysium (C)</p> Signup and view all the answers

Which part of the small bowel is most prominently affected by damage in celiac disease?

<p>Duodenum (D)</p> Signup and view all the answers

How do symptoms of celiac disease typically resolve?

<p>With a gluten-free diet (D)</p> Signup and view all the answers

What is the classic presentation of colonic diverticula?

<p>Abdominal pain with bloating and flatulence (C)</p> Signup and view all the answers

What is the most common type of colonic polyp?

<p>Hyperplastic polyps (D)</p> Signup and view all the answers

What genetic mutation is associated with the formation of adenomatous polyps?

<p>APC mutations (B)</p> Signup and view all the answers

What is the main cause of achalasia?

<p>Damage to ganglion cells in the myenteric plexus (D)</p> Signup and view all the answers

Which type of colonic polyp is benign but has premalignant potential?

<p>Adenomatous polyps (A)</p> Signup and view all the answers

Which of the following is NOT a clinical feature of achalasia?

<p>Increased risk for esophageal squamous cell carcinoma (D)</p> Signup and view all the answers

What is the role of dietary fiber in managing symptoms related to disturbed intestinal motility?

<p>Improves symptoms (D)</p> Signup and view all the answers

What happens in portal hypertension that leads to dilation of the esophageal vein?

<p>Back up of the left gastric vein into the esophageal vein (B)</p> Signup and view all the answers

What is the characteristic appearance of hyperplastic colonic polyps on microscopy?

<p>'Serrated' appearance (C)</p> Signup and view all the answers

Which condition is characterized by reflux of acid from the stomach due to reduced LES tone?

<p>Gastroesophageal reflux disease (GERD) (A)</p> Signup and view all the answers

'Bird-beak' sign on barium swallow study is associated with which condition?

<p>Achalasia (A)</p> Signup and view all the answers

What is the most common cause of death in cirrhosis?

<p>Rupture of dilated esophageal varices (A)</p> Signup and view all the answers

Which of the following is a risk factor associated with the development of diverticula?

<p>Straining during bowel movements (D)</p> Signup and view all the answers

Where do diverticula typically arise in the colonic wall?

<p>Along the vasa recta in the muscularis propria (C)</p> Signup and view all the answers

Which of the following complications can arise from a diverticulum causing attachment to a local structure?

<p>Appendicitis-like symptoms (D)</p> Signup and view all the answers

What is the classic presentation of angiodysplasia rupture?

<p>Hematochezia in an older adult (B)</p> Signup and view all the answers

Which area of the colon is most commonly affected by ischemic colitis?

<p>Cecum and right colon (B)</p> Signup and view all the answers

Which disorder results in thin-walled blood vessels and bleeding, especially in the mouth and GI tract?

<p>Hereditary hemorrhagic telangiectasia (D)</p> Signup and view all the answers

What is the goal of screening for colorectal carcinoma?

<p>To detect cancer early and remove adenomatous polyps before carcinoma develops (D)</p> Signup and view all the answers

How does left-sided colorectal carcinoma usually present?

<p>As a 'napkin-ring' lesion with decreased stool caliber and left lower quadrant pain (D)</p> Signup and view all the answers

What is associated with right-sided colorectal carcinoma?

<p>Iron-deficiency anemia and vague pain (A)</p> Signup and view all the answers

What does the 'T' in the staging of colorectal carcinoma represent?

<p>Depth of invasion (A)</p> Signup and view all the answers

Which serum tumor marker is useful for assessing treatment response and detecting recurrence in colorectal carcinoma?

<p>CEA (A)</p> Signup and view all the answers

At what age does screening for colorectal carcinoma usually begin?

<p>50 years (B)</p> Signup and view all the answers

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