Diuretics and Kidney Function
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Questions and Answers

What percentage of potassium from the glomerular filtrate is reabsorbed by the proximal convoluted tubules?

  • 70% (correct)
  • 50%
  • 90%
  • 30%

What is the result of inhibiting carbonic anhydrase?

  • Increased reabsorption of sodium and water
  • Increased reabsorption of chloride
  • Decreased reabsorption of bicarbonate, sodium, and water (correct)
  • Increased reabsorption of potassium

What is the primary site of action for osmotic diuretics?

  • Collecting ducts
  • Distal tubules
  • Loop of Henle
  • Proximal convoluted tubules (correct)

What is the effect of increased H+ concentration on potassium ion secretion?

<p>Exchanges H+ ions for sodium (C)</p> Signup and view all the answers

Which type of diuretics act on the ascending limb of the loop of Henle?

<p>Frusemide (C)</p> Signup and view all the answers

What is the main function of obligatory water reabsorption in the proximal convoluted tubules?

<p>To maintain osmotic balance (D)</p> Signup and view all the answers

What is the primary reason for using diuretics in congestive cardiac failure?

<p>To reduce edema (B)</p> Signup and view all the answers

What is the primary mechanism of action of thiazide diuretics?

<p>Inhibiting sodium reabsorption in the distal convoluted tubules (B)</p> Signup and view all the answers

What is the approximate flow rate of the filtrate when it reaches the loop of Henle?

<p>25 mL/min (C)</p> Signup and view all the answers

What is the approximate specific gravity of urine with an osmolality of 1200 mosmol/kg?

<p>1.032 (A)</p> Signup and view all the answers

Which type of diuretics inhibit sodium reabsorption and are also potassium-sparing?

<p>Aldosterone antagonists (A)</p> Signup and view all the answers

What is the primary purpose of urine analysis in clinical biochemistry?

<p>To detect abnormal constituents in urine (C)</p> Signup and view all the answers

What type of substances are completely reabsorbed and not excreted in urine at normal or low plasma levels?

<p>Threshold substances (D)</p> Signup and view all the answers

What is the primary mechanism of sodium reabsorption in the proximal convoluted tubules?

<p>Co-transport mechanism (A)</p> Signup and view all the answers

Which of the following inhibits the sodium-Pi co-transport system?

<p>Parathyroid hormone (A)</p> Signup and view all the answers

What is the net effect of sodium reabsorption in the proximal convoluted tubules?

<p>Reabsorption of sodium chloride along with glucose and amino acids (D)</p> Signup and view all the answers

What is the threshold value of glucose in plasma beyond which it is excreted in urine?

<p>180 mg/dL (A)</p> Signup and view all the answers

What is the purpose of the Na+ to H+ exchange system in the proximal convoluted tubules?

<p>To reabsorb sodium and secrete hydrogen ions (C)</p> Signup and view all the answers

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