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16 Questions

Which category of causes of Acute Kidney Injury (AKI) includes factors such as hypovolemia and decreased renal perfusion?

Prerenal

What is the term for the presence of excessive nitrogenous waste products in the blood?

Azotemia

What is the main action of most diuretics used clinically?

Reduce Na+ reabsorption

What is the term for the irreversible loss of functional nephrons in Chronic Kidney Disease (CKD)?

Nephron attrition

Which diuretic is used for glaucoma and prophylaxis for altitude sickness?

Carbonic anhydrase inhibitors

What is the most common cause of acute kidney injury (AKI) or acute renal failure (ARF) perioperatively?

Renal ischemia

What is the most common cause of perioperative AKI?

Renal ischemia

Which diuretic is associated with reduced urine concentrating ability and potassium loss?

Loop diuretics

What is the definition of oliguria?

Urine output < 0.5 ml/kg/hr

What is the most likely cause of oliguria?

Inadequate circulating fluid volume

What is the effect of carbonic anhydrase inhibitors on HCO3- reabsorption?

Dramatically reduce HCO3- reabsorption in the proximal tubule

What is the effect of loop diuretics on electrolyte excretion?

Large amounts of Na, K, Mg, etc. excreted

What is the most common cause of chronic kidney disease (CKD) or chronic renal failure (CRF)?

Renal ischemia

What is the effect of chronic kidney disease (CKD) on functioning nephrons?

Progressive and irreversible loss of functioning nephrons

What is the effect of chronic kidney disease (CKD) on GFR?

GFR drops below 60 ml/min/1.73 m2 for 3 months

What is the most common cause of acute kidney injury (AKI) or acute renal failure (ARF) perioperatively?

Renal ischemia

Explore the mechanisms of action of diuretics and their significance in kidney diseases, acute kidney injury, and chronic kidney disease. Understand the objectives related to diuretics and kidney disease including definitions, tests of glomerular filtration rate, and management strategies.

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