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Questions and Answers
Which of the following is a key function of drug delivery systems (DDS)?
Which of the following is a key function of drug delivery systems (DDS)?
- Prolonging pharmacokinetics (correct)
- Increasing uptake into off-target tissues
- Targeting healthy tissues
- Decreasing drug efficacy
What is the size range of most particle-based DDS?
What is the size range of most particle-based DDS?
- 50-100 nm
- 80-200 nm (correct)
- 200-500 nm
- 10-50 nm
Which therapeutic areas have approved the use of nanoparticle-based DDS?
Which therapeutic areas have approved the use of nanoparticle-based DDS?
- Cardiology and neurology
- Gastroenterology and rheumatology
- Endocrinology and dermatology
- Oncology and infectious diseases (correct)
Which mechanism can cause complement deposits on DDS?
Which mechanism can cause complement deposits on DDS?
What is the term used to describe the significant response caused by the release of anaphylatoxins?
What is the term used to describe the significant response caused by the release of anaphylatoxins?
Which symptoms are most severe and cardiovascular in nature?
Which symptoms are most severe and cardiovascular in nature?
Which of the following strategies is NOT used to reduce complement-associated side effects in drug delivery systems?
Which of the following strategies is NOT used to reduce complement-associated side effects in drug delivery systems?
Which organ takes the largest fraction of injected drug delivery systems (DDS)?
Which organ takes the largest fraction of injected drug delivery systems (DDS)?
Which of the following is NOT a way in which PEGylation affects the behavior of liposomal drugs?
Which of the following is NOT a way in which PEGylation affects the behavior of liposomal drugs?
Which of the following is NOT a cell involved in post-stroke inflammation?
Which of the following is NOT a cell involved in post-stroke inflammation?
Which class of MHC molecules is found on macrophages, dendritic cells, and B cells?
Which class of MHC molecules is found on macrophages, dendritic cells, and B cells?
Which type of interferon is involved in stimulating the expression of class II MHC molecules on antigen presenting cells (APCs)?
Which type of interferon is involved in stimulating the expression of class II MHC molecules on antigen presenting cells (APCs)?
Which molecule is noncovalently attached to the polymorphic α chain of class I MHC molecules?
Which molecule is noncovalently attached to the polymorphic α chain of class I MHC molecules?
Which type of immune cells produce IFN-𝞬 during innate immune reactions to microbes or during adaptive immune reactions?
Which type of immune cells produce IFN-𝞬 during innate immune reactions to microbes or during adaptive immune reactions?
Which of the following is an advantage of using microfluidic platforms for antibody discovery?
Which of the following is an advantage of using microfluidic platforms for antibody discovery?
What is the temperature at which the entire Cytomine workflow is carried out, except for the incubation steps?
What is the temperature at which the entire Cytomine workflow is carried out, except for the incubation steps?
What assays can be performed in Cytomine to detect and isolate antibody-secreting cells?
What assays can be performed in Cytomine to detect and isolate antibody-secreting cells?
Which domains of class I MHC molecules contain polymorphic residues?
Which domains of class I MHC molecules contain polymorphic residues?
Where are the polymorphic residues of class II MHC molecules located?
Where are the polymorphic residues of class II MHC molecules located?
Which cellular compartments are involved in the processing of cytosolic proteins for presentation on class I MHC molecules?
Which cellular compartments are involved in the processing of cytosolic proteins for presentation on class I MHC molecules?
Where are the peptides derived from protein antigens degraded in APCs for presentation on class II MHC molecules?
Where are the peptides derived from protein antigens degraded in APCs for presentation on class II MHC molecules?
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