Podcast
Questions and Answers
What is the primary driver of the concentration gradient in the interstitium of the thick ascending limb?
What is the primary driver of the concentration gradient in the interstitium of the thick ascending limb?
- Na+Cl- reabsorption (correct)
- K+ reabsorption
- Urea reabsorption
- H2O reabsorption
Which of the following statements is true about the counter-current multiplier mechanism?
Which of the following statements is true about the counter-current multiplier mechanism?
- It is a continuous process that can be envisioned as two independent processes. (correct)
- It is a process that occurs only in the proximal convoluted tubule.
- It is driven by the reabsorption of urea in the thick ascending limb.
- It is responsible for the reabsorption of Na+ in the distal convoluted tubule.
What is the role of the basolateral Na+/K+-ATPase in the thick ascending limb?
What is the role of the basolateral Na+/K+-ATPase in the thick ascending limb?
- To reabsorb K+ from the tubular fluid
- To secrete Na+ into the interstitium
- To maintain the low intracellular Na+ concentration (correct)
- To generate the concentration gradient in the interstitium
What percentage of sodium is reabsorbed in the proximal convoluted tubule?
What percentage of sodium is reabsorbed in the proximal convoluted tubule?
What is the primary function of the macula densa in the distal convoluted tubule?
What is the primary function of the macula densa in the distal convoluted tubule?
What is the primary mechanism of H2O reabsorption in the thick ascending limb?
What is the primary mechanism of H2O reabsorption in the thick ascending limb?
What is the primary function of the thin descending limb of the loop of Henle?
What is the primary function of the thin descending limb of the loop of Henle?
What is the role of the basolateral Na+/K+-ATPase in the thick ascending limb of the loop of Henle?
What is the role of the basolateral Na+/K+-ATPase in the thick ascending limb of the loop of Henle?
What is the effect of aldosterone on the abundance of ENaC channels in the distal convoluted tubule?
What is the effect of aldosterone on the abundance of ENaC channels in the distal convoluted tubule?
What is the primary site for elimination of waste and hydrogen ions in the nephron?
What is the primary site for elimination of waste and hydrogen ions in the nephron?
What is the percentage of chloride reabsorbed in the proximal convoluted tubule?
What is the percentage of chloride reabsorbed in the proximal convoluted tubule?
What is the main mechanism of urea reabsorption in the proximal convoluted tubule?
What is the main mechanism of urea reabsorption in the proximal convoluted tubule?
In the early distal convoluted tubule, what is the function of the luminal Na+/Cl- symporter?
In the early distal convoluted tubule, what is the function of the luminal Na+/Cl- symporter?
What is the primary function of the basolateral Na+/K+-ATPase in principal cells?
What is the primary function of the basolateral Na+/K+-ATPase in principal cells?
In the late distal convoluted tubule, what is the primary function of intercalated cells?
In the late distal convoluted tubule, what is the primary function of intercalated cells?
What is the effect of aldosterone on the late distal convoluted tubule and collecting tubules?
What is the effect of aldosterone on the late distal convoluted tubule and collecting tubules?
What is the characteristic of the epithelium in the late distal convoluted tubule and collecting tubules?
What is the characteristic of the epithelium in the late distal convoluted tubule and collecting tubules?
What is the primary function of the Ca2+ reabsorption mechanism in the early distal convoluted tubule?
What is the primary function of the Ca2+ reabsorption mechanism in the early distal convoluted tubule?
