FGP 1 Quiz

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Questions and Answers

What is the primary affected area in lichen sclerosus et atrophicus?

  • Back and shoulders
  • Anogenital area (correct)
  • Lower limbs
  • Face and neck

Which of the following is a possible pathogenesis for lichen sclerosus et atrophicus?

  • Bacterial infection
  • Excessive sun exposure
  • High estrogen state
  • Autoimmunity (correct)

Which of the following is a characteristic feature of lichen sclerosus et atrophicus?

  • Blistering and oozing lesions
  • Raised, itchy papules
  • Red, scaly patches
  • Smooth, white parchment-like areas (correct)

What are the reported correlations in terms of genetic susceptibility for lichen sclerosus et atrophicus?

<p>High correlation between twins and family members (D)</p> Signup and view all the answers

Which group of women primarily have lichen sclerosus et atrophicus?

<p>Women with low estrogen state (C)</p> Signup and view all the answers

Which condition is characterized by vulval and perianal itching, pain from skin trauma, and dysuria?

<p>Lichen sclerosus (D)</p> Signup and view all the answers

Which of the following is not a known infectious cause of lichen sclerosus et atrophicus?

<p>Herpes simplex virus (B)</p> Signup and view all the answers

Which condition is a non-specific response to recurrent scratching to relieve pruritus, characterized by white plaques and marked epidermal thickening?

<p>Lichen simplex chronicus (A)</p> Signup and view all the answers

Which condition is characterized by verrucous lesions on the vulva, perineum, and vagina, caused by sexually transmitted HPV types 6 or 11?

<p>Condyloma acuminatum (C)</p> Signup and view all the answers

Which condition is associated with dysplasia, varying degrees of atypia, and has not invaded the basement membrane but has invasive potential?

<p>Vulval intraepithelial neoplasia (B)</p> Signup and view all the answers

What is the main issue in lichen sclerosus?

<p>Increased risk of vulvar cancer (B)</p> Signup and view all the answers

What is the characteristic histological feature of lichen simplex chronicus?

<p>Marked epidermal thickening (D)</p> Signup and view all the answers

What is the cause of condyloma acuminatum?

<p>Viral infection (HPV types 6 or 11) (A)</p> Signup and view all the answers

What is a common symptom of lichen sclerosus?

<p>Pain from skin trauma (A)</p> Signup and view all the answers

What type of women are most commonly affected by classic (VIN)?

<p>Pre-menopausal women (A)</p> Signup and view all the answers

What is a distinguishing feature of vulval intraepithelial neoplasia in postmenopausal women?

<p>Unifocal presentation (D)</p> Signup and view all the answers

What is the uncertain pathogenesis of lichen sclerosus et atrophicus thought to involve?

<p>Autoimmunity, such as autoantibody production against ECMP1 (B)</p> Signup and view all the answers

What is the characteristic feature of squamous vulvar intraepithelial neoplasia (VIN)?

<p>Dysplasia, varying degrees of atypia, and invasive potential without invading the basement membrane (A)</p> Signup and view all the answers

Which condition is a non-specific response to recurrent scratching to relieve pruritus, characterized by white plaques and marked epidermal thickening?

<p>Squamous cell hyperplasia (lichen simplex chronicus) (B)</p> Signup and view all the answers

What is the primary affected area in lichen sclerosus et atrophicus?

<p>Anogenital area (B)</p> Signup and view all the answers

What is the distinguishing feature of vulval intraepithelial neoplasia in postmenopausal women?

<p>Thinning of the epidermis with loss of rete ridges (B)</p> Signup and view all the answers

What is the main issue in lichen sclerosus et atrophicus?

<p>Smooth, white parchment-like areas due to papules or macules coalescing (B)</p> Signup and view all the answers

What is the distinguishing feature of vulval intraepithelial neoplasia in postmenopausal women?

<p>Unifocal lesions not graded (D)</p> Signup and view all the answers

Which condition is associated with dysplasia, varying degrees of atypia, and has not invaded the basement membrane but has invasive potential?

<p>Vulval Intraepithelial Neoplasia (A)</p> Signup and view all the answers

What is the characteristic histological feature of lichen simplex chronicus?

<p>Marked epidermal thickening with significant surface hyperkeratosis (C)</p> Signup and view all the answers

Which condition is characterized by vulval and perianal itching, pain from skin trauma, and dysuria?

<p>Lichen sclerosus et atrophicus (A)</p> Signup and view all the answers

What is the cause of condyloma acuminatum?

<p>Benign Exophytic Lesions (C)</p> Signup and view all the answers

What type of women are most commonly affected by classic (VIN)?

<p>Premenopausal women (B)</p> Signup and view all the answers

What are the reported correlations in terms of genetic susceptibility for lichen sclerosus et atrophicus?

<p>Uncertain genetic correlations have been reported. (B)</p> Signup and view all the answers

[Difficult] What is the uncertain pathogenesis of lichen sclerosus et atrophicus thought to involve?

<p>Uncertain pathogenesis thought to involve autoimmune or genetic factors. (C)</p> Signup and view all the answers

[Difficult] What is the main issue in lichen sclerosus et atrophicus?

<p>Main issues are the scarring complications of the disease. (C)</p> Signup and view all the answers

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