Disorders of Energy Balance and Disease States Quiz
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Questions and Answers

What is the main focus of the Adolph EF (1947) experiments mentioned?

  • Daily circadian cycle for energy stores
  • Short term satiety mechanisms
  • Exchange of blood between rats (correct)
  • Long term regulation of hunger

What was one of the misconceptions that delayed the identification of the circulating factor mentioned in the experiments?

  • The factor was lipid soluble (correct)
  • The factor was a protein
  • The factor was genetic
  • The factor was water-soluble

What is the role of the Ventromedial Nucleus (VMN) of the hypothalamus?

  • Stores body fat
  • Regulates blood circulation
  • Controls hunger and satiety (correct)
  • Regulates body temperature

What did the Parabiosis experiments by Coleman (1973) demonstrate?

<p>Circulating factors between fat and lean rats (B)</p> Signup and view all the answers

What is the purpose of the Circadian Regulatory Cycle for Energy Stores mentioned in the text?

<p>Drive eating patterns based on day-night cycle (C)</p> Signup and view all the answers

Why was the correlation of body weight with fat stores considered poor in the short term according to the text?

<p>Rapid changes in body composition (A)</p> Signup and view all the answers

What happens when energy input equals energy output?

<p>Increased storage (B)</p> Signup and view all the answers

Which statement best describes the relationship between energy stores and body mass?

<p>Changes in energy stores correlate with body mass if lean body mass remains constant. (A)</p> Signup and view all the answers

What is a characteristic of changes in body weight over periods longer than 24 hours?

<p>They are often correlated with changes in adipose tissue energy stores. (D)</p> Signup and view all the answers

How precisely do we regulate our energy stores according to the text?

<p>Very precisely, with long-term regulation being precise. (D)</p> Signup and view all the answers

What does storage of 1 kg fat represent in terms of energy storage?

<p>Storage of 39 MJ of energy (A)</p> Signup and view all the answers

In the context of regulating energy, what does the text propose as a controversial aspect?

<p>Adjusting metabolic expenditure to balance intake (A)</p> Signup and view all the answers

What is one reason why severely obese humans with no detectable mutations in the Ob gene can still be obese?

<p>Due to mutations in the receptor for leptin (B)</p> Signup and view all the answers

What is a possible consequence of low leptin levels in humans?

<p>Impaired reproductive signaling (A)</p> Signup and view all the answers

Which factor has been found to play a role in the aetiology of obesity in some severely obese individuals with no Ob gene mutations?

<p>Insulin resistance (A)</p> Signup and view all the answers

How was the obesity of individuals with pure leptin deficiency successfully treated?

<p>Through leptin administration (C)</p> Signup and view all the answers

What feedback system is involved in regulating energy stores and metabolic activity level?

<p>Leptin receptors and sympathetic neural activity (C)</p> Signup and view all the answers

Why are starving people more susceptible to infection according to the text?

<p>Because of low adipose tissue size (A)</p> Signup and view all the answers

What is the function of the ventromedial nucleus (VMN) of the hypothalamus?

<p>Control the utilization and storage of body fat (A)</p> Signup and view all the answers

Lesions of the ventromedial nucleus (VMN) lead to:

<p>Hyperphagia and obesity (D)</p> Signup and view all the answers

Which type of inhibition does the ventromedial nucleus (VMN) exert on lipogenesis control?

<p>Adrenergic inhibition (C)</p> Signup and view all the answers

What happens when there is a bilateral lesion of the ventromedial nucleus of the hypothalamus?

<p>Hyperphagia and lipogenesis (A)</p> Signup and view all the answers

What is the main function of the lateral hypothalamus?

<p>Process afferent sensory information (C)</p> Signup and view all the answers

Which protein is produced by adipose tissue itself and plays a role in long-term regulation of hunger?

<p>Leptin (A)</p> Signup and view all the answers

What is the role of low leptin levels in relation to helper T lymphocytes?

<p>Inhibit the immune response (B)</p> Signup and view all the answers

Which hormone is known to be anorexigenic based on the text provided?

<p>GLP-1: glucagon-like peptide 1 (A)</p> Signup and view all the answers

What happens when leptin receptors on helper T lymphocytes are insufficiently bound?

<p>Inhibit the immune response (D)</p> Signup and view all the answers

Which hormone is secreted by the colon and is anorexigenic?

<p>OXM: oxyntomodulin (A)</p> Signup and view all the answers

What is the function of PYY: peptide YY in the lower intestine?

<p>Inhibit food intake (D)</p> Signup and view all the answers

Which hormone affects food intake and is secreted by the small intestine according to the information provided?

<p>GLP-1: glucagon-like peptide 1 (C)</p> Signup and view all the answers

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