Disc Prolapse and Neurological Signs Quiz
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Questions and Answers

What is a common characteristic of lower motor neuron (LMN) lesions?

  • Spastic weakness
  • Little atrophy
  • Hyperreflexia
  • Atrophy (correct)
  • Which of these signs is indicative of upper motor neuron (UMN) lesions?

  • Fasciculations
  • Flaccid paralysis
  • Little atrophy (correct)
  • Hypo/areflexia
  • What is the likely outcome if the L4/L5 disc is affected?

  • Impact on the L5 nerve root (correct)
  • Impact on the L2 nerve root
  • Impact on the S1 nerve root
  • Impact on the L3 nerve root
  • What is a common initial symptom reduction period for most disc prolapse cases?

    <p>3 weeks (D)</p> Signup and view all the answers

    Which stage of disc herniation is characterized by the inner disc pushing further into the outer layer without breaking through?

    <p>Stage 2 prolapsed disc (C)</p> Signup and view all the answers

    Which imaging technique may still show a bulging disc even after symptomatic resolution?

    <p>MRI (C)</p> Signup and view all the answers

    Disc prolapse commonly occurs in which part of the spine?

    <p>Lower lumbar region (C)</p> Signup and view all the answers

    In cases of thoracolumbar syndrome, which nerves are implicated in referred pain to the buttocks and hip?

    <p>Cluneal nerves from T11-L5 (B)</p> Signup and view all the answers

    What characterizes the progression from disc degeneration to a prolapsed disc?

    <p>Annular fibres weaken without nucleus protrusion (D)</p> Signup and view all the answers

    What is a recommended position to alleviate pain in disc prolapse patients?

    <p>Antalgic positions (D)</p> Signup and view all the answers

    Which neurological sign is most likely associated with upper motor neuron lesions?

    <p>Clonus (D)</p> Signup and view all the answers

    What is the typical time frame for resorption and symptomatic resolution in disc prolapse?

    <p>6-8 weeks (A)</p> Signup and view all the answers

    What is the typical location where lumbar nerve roots exit the spine?

    <p>Below the vertebral pedicle (A)</p> Signup and view all the answers

    Which condition is characterized by irritation of the cluneal nerves?

    <p>Maigne’s syndrome (C)</p> Signup and view all the answers

    Which symptom is NOT commonly associated with lateral spinal stenosis?

    <p>Bilateral weakness (C)</p> Signup and view all the answers

    What is a hallmark test result expected in a patient with spinal stenosis?

    <p>Decreased reflexes (D)</p> Signup and view all the answers

    What is a contraindicated treatment for disc prolapse?

    <p>Rotatory adjustments at the affected level (B)</p> Signup and view all the answers

    Which of the following conditions is a risk factor for developing spinal stenosis at an earlier age?

    <p>Engaging in contact sports (C)</p> Signup and view all the answers

    Which factor may predispose an individual to facet and capsular irritation in thoracolumbar syndrome?

    <p>Orientation of the facets changing (A)</p> Signup and view all the answers

    What type of symptoms are typically seen with central spinal stenosis?

    <p>Bilateral symptoms (D)</p> Signup and view all the answers

    Which condition can result from severe lumbar stenosis?

    <p>Cauda equina syndrome (C)</p> Signup and view all the answers

    What are common aggravating factors for symptoms of lateral spinal stenosis?

    <p>Extension and ipsilateral lateral flexion (D)</p> Signup and view all the answers

    What is the primary mechanism leading to spinal stenosis as a result of osteoarthritis?

    <p>Formation of synovial cysts (B)</p> Signup and view all the answers

    What type of weakness is commonly associated with lateral spinal stenosis?

    <p>Flaccid weakness (B)</p> Signup and view all the answers

    Flashcards

    Lateral Spinal Stenosis

    Compression of the nerve root as it exits the spinal canal, typically causing unilateral symptoms.

    Foraminal Spinal Stenosis

    Compression of the nerve root within the intervertebral foramen (IVF), often mimicking lateral stenosis.

    Central Spinal Stenosis

    Compression of the spinal cord within the spinal canal, usually causing bilateral symptoms.

    Cauda Equina Syndrome

    A rare, but serious condition resulting from severe lumbar stenosis, affecting the cauda equina nerve roots.

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    Osteoarthritis

    A common cause of spinal stenosis due to age-related wear and tear on the joints.

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    Synovial Cysts

    Fluid-filled sacs that can develop in the joints, contributing to stenosis.

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    Facet Joint Hypertrophy

    An overgrowth of tissue in the facet joints, narrowing the IVF.

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    Bone Spurs (Osteophytes)

    Abnormal bone growths that can develop due to osteoarthritis, contributing to spinal stenosis.

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    Disc Prolapse Natural History

    Most disc prolapses will heal on their own without surgery.

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    Disc Prolapse Treatment Goals

    The period of pain from a disc prolapse can be shortened with appropriate treatment.

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    Rotatory Adjustments and Disc Prolapse

    Rotatory adjustments to the spine are strongly discouraged in cases of disc prolapse.

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    What is Thoracolumbar Syndrome?

    Thoracolumbar Syndrome (TLS) is a condition affecting the cluneal nerves, causing buttock and hip pain.

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    Cluneal Nerves and TLS

    The cluneal nerves are sensory branches of the lower thoracic and upper lumbar nerves.

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    TLS Pathophysiology (Maigne's Syndrome)

    TLS is thought to be caused by irritation of the cluneal nerves due to instability and overuse of the thoracolumbar junction.

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    Why is the Thoracolumbar Junction Unstable?

    The thoracolumbar junction is less stable than other areas due to the lack of rib attachment.

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    Facet Joint Orientation in Thoracolumbar Syndrome

    The facet joints change orientation at the thoracolumbar junction, which can lead to overload and irritation.

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    What is the corticospinal tract?

    The motor pathway that connects the brain to the spinal cord, consisting of upper motor neurons (UMN) and lower motor neurons (LMN).

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    What is the cauda equina?

    A collection of nerve roots that extend from the spinal cord below the level of the conus medullaris.

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    What is the dural sac?

    The protective sheath that surrounds the spinal cord and nerve roots, extending down to the level of L1/2.

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    What is a disc prolapse?

    A condition where the nucleus pulposus of a disc protrudes through the annulus fibrosis.

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    What is Stage 1 disc degeneration?

    The stage of disc degeneration where weakness in the annular fibers occurs, but the nucleus pulposus is still contained.

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    What is Stage 2 disc herniation?

    The stage of disc herniation where the nucleus pulposus pushes toward the outer layer, but doesn't fully break through.

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    What is the intervertebral foramen?

    The space between a vertebral body and its pedicle, where a nerve root exits the spinal canal.

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    What is the most common location for lumbar disc prolapse?

    The most common location for disc prolapse in the lumbar spine, usually affecting the L5 nerve root.

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    Study Notes

    Pre-Learning Spinal Nerve Root Lesions

    • Spinal nerve roots travel downward via the dural sac or thecal sac
    • They need to travel vertically to the spinal level
    • Spinal nerve exits the IVF below the vertebral pedicle
    • L4/L5 disc most commonly impacted by disc prolapse
    • Occasionally L4 is affected, but more severe herniation
    • Disc prolapse is a tear in the annular fibres allowing the nucleus pulposus to push outwards
    • Typically tends to the posterior-lateral aspect of the discs
    • Cervical spine - lower cervical most common
    • Thoracic spine rarely affected due to stabilisation of rib cage
    • May see from trauma or conditions that predispose uneven weight transfer

    Corticospinal Tract

    • Composed of upper motor neurons (UMN) and lower motor neurons (LMN)
    • UMN is motor cortex to the spinal level (synapse)
    • LMN is at the spinal level (synapse) to the muscle fibre (synapse) to muscle fibre

    LMN and UMN Signs

    • LMN Signs:
      • Flaccid weakness or paralysis
      • Atrophy
      • Fasciculations
      • Hypo/areflexia
    • UMN Signs:
      • Spastic weakness or paralysis
      • Little atrophy (disuse over time)
      • Hyperreflexia or clonus

    Disc Prolapse Classification

    • Four stages of disc herniation: degeneration, prolapse, extrusion, sequestration
    • AKA bulge, slipped disc, prolapse
    • Stage 1 - Disc Degeneration
      • Due to chemical changes, years of physical labour or acute or chronic stress
      • Flexion/rotation injury often
      • Annular fibres weaken, but nucleus remains encased
      • May be present if had previous prolapse but elasticity in fibres not able to allow for full resorption
    • Stage 2 - Prolapsed Disc
      • The inner disc pushes further into the outer layer of the disc
      • Gives a prolapsed appearance
      • Considered a bulging disc
      • The inner nuclear material has still not broken through the fibrous wall
      • 2 clinical outcomes:
        • Bulge may lead to chemical irritation of nearby nerves without actual compression
        • The bulge may compress nearby nerves or other spinal structures
    • Stage 3 - Extrusion
      • The gel-like nucleus eventually breaks through the outer wall
      • Even though it breaks through, the nucleus remains within the disc
      • May have more severe symptoms due to greater damage
      • Confirmation of MRI finding used to be a clinical indication of surgical requirements in the past
      • Recent evidence extrusion has greatest tendency to decrease in size with conservative management
    • Stage 4 - Sequestration
      • The nucleus breaks through the outer wall and eventually spills out of the spinal disc into the spinal canal
      • The chemical components of the nucleus material can cause nerve inflammation, irritation, or pain to the effected nerve root
      • Nerve roots above/below
      • Cauda equina (if in lumbar spine)

    Disc Prolapse - Location Classification

    • Classified by axial (from underneath) view on MRI
    • Disc = clock
      • 6 o'clock = central disc herniation
      • 5 or 7 o'clock = paracentral disc herniation (AKA posterolateral disc herniation)
      • 4 or 8 o'clock = foraminal disc herniation
    • Located lateral to formina = far lateral disc herniation
    • Central and paracentral most common
    • Forminal and far lateral less common but more severe
    • Conservative care not as beneficial

    Disc Prolapse

    • Typically an acute disc event occurring from age 25 to 50
    • Younger discs stronger unless put into early heavy challenge or trauma
    • Older discs desiccate and so are more stable
      • Disc bulge possible but is due to loss of elasticity in annular fibres
    • Often not symptomatic
    • Is a long-term flexion/rotation type injury over months-years
    • Often have an "inciting event" that triggers pain (e.g., lifting)
    • Event can be non-traumatic (Valsalva type manoeuvre, rotation)

    Disc Prolapse - Hallmark Characteristics

    • Burning/electrical LEG or ARM pain
    • Two main pain mechanisms for lower extremity pain
      • Inflammatory mediators irritating nerve root (prostaglandins, leukotrienes, nitric oxide...)
      • Mechanical pressure onto the nerve root

    Disc Prolapse - Symptoms

    • Neurogenic pain or paraesthesia in a dermatome consistent and severe (7-8) for 3 weeks
    • Pain aggravated by flexion, IL lateral flexion, IL rotation
    • Pain may be reduced with CL lateral flexion – will not totally relieve
    • Valsalva type manoeuvres increase pain (cough, strain, sneeze)
    • Back pain due to annular tear and muscle spasm
    • DO NOT remove spasm – it's a protective mechanism - avoid further damage

    Disc Prolapse - Other Symptoms

    • Myotomal weakness – flaccid type
    • Reduced reflex
    • May have exaggerated reflex below level of bulge
    • If severe and affecting nerve roots below it (lumbar spine more common) - Observe antalgic gait

    Disc Herniation Imaging

    • MRI 2-3 months via NHS
      • Many disc herniations likely resorbed
    • Private MRI fast but expensive
    • If minor - won't change your treatment plan
    • 30% of population =asymptomatic disc herniation
    • "label" onto patient affecting behaviour
    • The longer a nerve is compressed, the more likely permanent damage is to occur
    • Conservative Rx not appropriate

    Disc Prolapse - Refer If...

    • Significant functional weakness (3 or below)
    • Progressive neurological deficit
      • More than 1 nerve root impacted
    • Unusually severe pain (7-8 normal)
    • Recovery not meeting timeframes
    • Signs of cauda equina
    • If occurred due to trauma (e.g. MVC) and fracture suspected

    Natural History

    • Most disc prolapse will fully resorb on their own
    • Typically should have symptomatic reduction around 3 weeks
    • Typically should have resorption and symptomatic resolution 6-8 weeks
    • Some patients experience symptomatic resolution but "bulging disc" may remain visible on an MRI
    • Loss of elasticity of annular fibres although the disc is healed
    • No surgery typically required
    • Some patients continue to have residual symptoms from bulge remaining as above or nerve not gliding well in its sheath
    • If due to annular fibres losing elasticity, may need surgery to remove

    Disc Prolapse - Treatment

    • Treatment may help to reduce symptomatic period
    • Improving blood flow
    • Improving biomechanics around the effected level
    • Advice to avoid exacerbation of inflammatory cycle
      • Avoid things that make the pain go towards the extremity (e.g., flexion)
    • Positions that alleviate the pain or make it disappear from extremities are recommended (antalgic)
    • Rotatory adjustments at the level CONTRAINDICATED

    Thoracolumbar Syndrome

    • AKA Maigne's syndrome
    • Maigne's syndrome actually a blanket diagnosis also looking at facet irritation (facet irritation of the lower portion of the thoracic spine and/or the upper lumbar spine)
    • Definition: Irritation of the cluneal nerves leading to referred pain in the buttocks and hip
    • Cluneal nerves – purely sensory branches of upper lumbar and lower thoracic nerves (T11 - L5 implicated)
    • Superior cluneal nerves most commonly implicated
    • Pathophysiology – not clearly understood
      • Maigne's syndrome:
        • TL junction is less stable, bottom 2 ribs are not attached
        • Facet orientation changes in this region from a frontal plane in the thoracic to a sagittal plane in the lumbar
        • May predispose area to overload leading to facet and capsular irritation which irritate SCN
      • Cluneal nerve entrapment:
        • SCN has to pass through the psoas major, lumbar paraspinals, and QL
        • Then passes through the TL fascia
        • Hypertonic muscles and thickening of fascial may lead to neural tension or compression
    • Who gets it?
      • Very little known - highly underdiagnosed condition
      • Instability – trauma or hypermobility may predispose
      • Hypomobility of the TL junction
    • Women 64+ may be common population group
    • Symptoms:
      • Pain will be aggravated by prolonged walking, extension, and rotation of the spine
      • If other aspects of nerve irritated, may see flexion/squatting/sitting – less common
      • Pain characterized typically as deep and aching
    • Referral pattern and visual representation of cluneal nerves
      • Posterior pelvis (1), lateral thigh (2), and inguinal region (3)
    • Treatment:
      • Case studies – suggest that conservative care may help
        • Manipulation of TL - hypomobility
        • Strengthening/stabilisation of TL - instability
        • Graston and myofascial release (muscles/fascia)
        • Stretching of muscles
        • Cluneal nerve flossing (modified sciatic floss)
      • Medically - facet injection provides short-term relief
      • Radio frequency ablation may provide longer-term results

    Spinal Stenosis

    • Stenosis = narrow

    • Can be anything from a cyst, tumour, syrinx

    • Most commonly degenerative changes to the spine (in class – this is the type we are discussing!)

    • Three major types:

      • Central: Compresses the central cord (discussed in the spinal cord lecture)
      • Lateral: Compression as it exits the spinal canal
      • Foraminal: Compression around the intervertebral foramen
        • Foraminal and lateral look exactly the same clinically – unilateral presentation on a nerve root
    • Pathophysiology

      • Osteoarthritis
        • Formation of synovial cysts
        • Hypertrophy of the facet joints
        • Bone spur formation (osteophyte) enclosing IVF
    • Effect (Lateral Spinal Stenosis):

      • 65+ unless have risk factors for earlier degeneration
      • Trauma, contact sports, smoking...
      • May report insidious, intermittent diffuse, crampy pain with paraesthesia
      • If outright nerve compression: Burning or electrical pain
      • Flaccid weakness, atrophy, a/hyporeflexia
      • Would be relieved by opening manoeuvres (flexion, contralateral lateral flexion)
      • Aggravated by closing manoeuvres (extension, ipsilateral lateral flexion)

    Condition Revision (Flashcard!)

    • On your flashcard, put in:

      • What is it – basic definition: This refers to a fundamental understanding of the medical condition in question, including its pathophysiology, etiology, and clinical presentation. It involves defining the disease, its progression, and how it varies from other similar conditions, providing an essential foundation for diagnosis and treatment.
      • Who gets it – main population or risk factors: Identifying the demographic groups that are most susceptible to the condition. This includes age, gender, genetic predispositions, environmental exposures, lifestyle choices, and existing health conditions that may contribute to the increased risk of developing the disease.
      • Hallmark symptoms – things that HAVE to be there: These are the key clinical manifestations that are essential for diagnosing the condition. Recognizing these symptoms is crucial, as their presence can help distinguish the disease from other similar conditions, guiding healthcare professionals in their assessments.
      • Hallmark tests – primary testing you would do with the expected abnormal results: This encompasses the specific diagnostic tests and examinations routinely employed to confirm the presence of the disease. The choice of tests may vary based on the suspected condition and typically includes laboratory tests, imaging studies, or biopsies that yield characteristic abnormalities associated with the disease.

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    Description

    Test your knowledge on lower and upper motor neuron lesions, disc prolapse, and related symptoms. This quiz covers key characteristics, imaging techniques, and typical outcomes associated with spinal disc issues. Perfect for students studying neurology or physical therapy.

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