Digestive System Overview and Stomach Structure
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Questions and Answers

Which region of the stomach is primarily responsible for food secretion and storage?

  • Fundus (correct)
  • Body (correct)
  • Cardia
  • Pyloric region
  • What type of epithelium lines the stomach and secretes mucus?

  • Simple columnar (correct)
  • Stratified squamous
  • Transitional
  • Simple cuboidal
  • Which gastric cells are primarily responsible for secreting neutral mucus?

  • Chief cells
  • Mucous neck cells
  • Surface mucus cells (correct)
  • Parietal cells
  • What is the function of the large intestine in the gastrointestinal tract?

    <p>Elimination of residues and water absorption (C)</p> Signup and view all the answers

    Which layer of the gastrointestinal tract wall contains blood vessels, nerves, and lymphatics?

    <p>Submucosa (B)</p> Signup and view all the answers

    What is the mechanical action of the stomach primarily facilitated by?

    <p>Three muscular layers in different orientations (A)</p> Signup and view all the answers

    Which region of the stomach contains mucous-secreting glands?

    <p>Cardia (C)</p> Signup and view all the answers

    What is the main role of the small intestine in the gastrointestinal tract?

    <p>Digestion and absorption (A)</p> Signup and view all the answers

    Which layer of the stomach wall includes gastric pits?

    <p>Mucosa (C)</p> Signup and view all the answers

    The type of connective tissue primarily found in the lamina propria of the gastrointestinal tract is classified as:

    <p>Loose connective tissue (B)</p> Signup and view all the answers

    Which cells in the gastric glands are primarily responsible for secreting hydrochloric acid (HCl)?

    <p>Parietal cells (A)</p> Signup and view all the answers

    What is the primary function of Chief (Peptic) cells in the stomach?

    <p>Secrete pepsinogen (A)</p> Signup and view all the answers

    Which part of the small intestine is primarily responsible for the absorption of nutrients?

    <p>Jejunum (A)</p> Signup and view all the answers

    What structural adaptation of the small intestine increases surface area the most?

    <p>Microvilli (B)</p> Signup and view all the answers

    Which gland is specifically located in the submucosa of the duodenum?

    <p>Brunner's glands (C)</p> Signup and view all the answers

    What is the primary cellular type lining the mucosa of the small intestine?

    <p>Simple columnar cells (A)</p> Signup and view all the answers

    Which layer of the gastrointestinal tract is primarily responsible for peristalsis?

    <p>Musculosa (D)</p> Signup and view all the answers

    Which structure is responsible for the production of hormones such as gastrin?

    <p>Entero-endocrine cells (B)</p> Signup and view all the answers

    What characterizes the pyloric glands in the stomach?

    <p>Highly convoluted with long pits (A)</p> Signup and view all the answers

    In which section of the small intestine would you most likely find Payer's patches?

    <p>Ileum (A)</p> Signup and view all the answers

    What is the primary function of beta cells in the Islets of Langerhans?

    <p>Release insulin hormone (B)</p> Signup and view all the answers

    What is the main type of epithelium that lines the interlobular ducts in the pancreas?

    <p>Simple cuboidal epithelium (D)</p> Signup and view all the answers

    How does the hepatic artery contribute to the liver's blood supply?

    <p>Supplies oxygen-rich blood (A)</p> Signup and view all the answers

    What characterizes the structure of a classic hepatic lobule?

    <p>Hexagonal mass of hepatocytes drained by a central vein (C)</p> Signup and view all the answers

    Which cells are responsible for secreting glucagon in the Islets of Langerhans?

    <p>Alpha cells (C)</p> Signup and view all the answers

    Which type of cells line the main pancreatic duct?

    <p>Simple columnar cells with goblet cells (D)</p> Signup and view all the answers

    What is the major metabolic function of the liver?

    <p>Synthesis of glucose and plasma proteins (A)</p> Signup and view all the answers

    What is the primary function of absorptive columnar cells in the intestinal mucosa?

    <p>Absorbing nutrients through microvilli (D)</p> Signup and view all the answers

    What type of cells are centroacinar cells that are associated with pancreatic function?

    <p>Squamous cells lining acini (A)</p> Signup and view all the answers

    Which type of cell in the intestinal mucosa is primarily responsible for secreting hormones?

    <p>Enteroendocrine cells (C)</p> Signup and view all the answers

    What distinguishes hepatic sinusoids from regular capillaries?

    <p>Larger diameter and fenestrated walls (D)</p> Signup and view all the answers

    Which layer of the gastrointestinal tract is characterized by the presence of inner circular and outer longitudinal muscle layers?

    <p>Musculosa (D)</p> Signup and view all the answers

    What type of secretion does the liver perform as an exocrine gland?

    <p>Bile secretion (A)</p> Signup and view all the answers

    What is a significant difference between the epithelial lining of the large intestine and that of the small intestine?

    <p>The large intestine has no villi (A)</p> Signup and view all the answers

    Paneth cells in the intestinal mucosa are responsible for which function?

    <p>Killing bacteria through lysozyme secretion (B)</p> Signup and view all the answers

    Which of the following accurately describes M-cells in the intestinal mucosa?

    <p>Antigen presenting cells that transport antigens (C)</p> Signup and view all the answers

    What is the primary role of the pancreas's exocrine portion?

    <p>Secreting digestive enzymes into the small intestine (C)</p> Signup and view all the answers

    Which structure in the large intestine helps with water absorption and mucous production?

    <p>Crypts (D)</p> Signup and view all the answers

    Which glands associated with the digestive tract secrete insulin and glucagon?

    <p>Pancreas (C)</p> Signup and view all the answers

    In the structure of the large intestine, which of the following is NOT present?

    <p>Villi (D)</p> Signup and view all the answers

    Flashcards

    Gastrointestinal Tract (GIT)

    The tube-like passageway responsible for food processing, from mouth to anus.

    Stomach Function

    Food storage and initial digestion into chyme (a thick liquid).

    Stomach Anatomy Components

    Cardia, fundus, body, and pyloric regions are the main parts of the stomach.

    Stomach Wall Layers

    Mucosa (inner lining), submucosa (connective tissue), muscularis (muscle layer), and serosa (outer membrane).

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    Epithelium of Small Intestine

    Simple columnar epithelium forms the lining of the small intestine

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    GIT Wall Mucosa

    The inner lining of the GIT, including the epithelium and lamina propria layers.

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    Muscularis Mucosae

    The smooth muscle layer within the Mucosa, involved in local movement.

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    Chyme

    The partially digested, semi-liquid mass of food in the stomach.

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    Fundic Glands

    Glands located in the stomach fundus, responsible for producing digestive juices.

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    GIT Function: Digestion

    Breaking down complex food molecules into simpler ones.

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    Parietal Cells

    Stomach cells that secrete hydrochloric acid (HCl) and intrinsic factor.

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    Chief Cells

    Stomach cells that secrete pepsinogen, a precursor to pepsin.

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    Enteroendocrine Cells

    Stomach cells that release hormones like gastrin, serotonin, and histamine into the bloodstream.

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    Pylorus of Stomach

    The distal portion of the stomach that connects to the duodenum.

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    Small Intestine Parts

    Duodenum, Jejunum, and Ileum constitute the small intestine, responsible for digestion and absorption.

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    Plicae Circularis

    Folds in the small intestine mucosa, increasing surface area for absorption.

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    Villi of Small Intestine

    Finger-like projections in the small intestine lining, further increasing surface area.

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    Brunner's glands

    Mucus-secreting glands in the duodenum.

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    Payer's patches

    Lymphoid follicles in the ileum.

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    Small Intestine Wall Layers

    The small intestine has mucosa, submucosa, muscularis, and serosa layers.

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    Villi

    Finger-like projections found in the small intestine, increasing surface area for nutrient absorption.

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    Goblet cells

    Unicellular glands found in the intestinal mucosa, secreting mucus to lubricate and protect the lining.

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    Paneth cells

    Specialized cells at the base of intestinal crypts, producing antimicrobial lysozymes.

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    M-cells

    Cells sampling antigens from the lumen and presenting them to immune cells in the intestinal mucosa.

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    Large intestine function

    Primary site for water absorption and production of mucus for lubrication, forming feces from digested food.

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    Tenia coli

    Three bands of longitudinal smooth muscle in the large intestine, responsible for its characteristic pouch-like shape.

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    Appendices epiploicae

    Small pouches of peritoneum filled with fat, attached to the large intestine.

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    Pancreas function

    A mixed gland, producing digestive enzymes (exocrine) and hormones regulating blood sugar (endocrine).

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    Pancreatic juice

    Secreted by the exocrine pancreas, contains enzymes like trypsin, chymotrypsin, amylase, and lipase.

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    Pancreatic Acinus Cells

    Pyramid-shaped cells that produce and secrete digestive enzymes, responsible for the exocrine function of the pancreas.

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    Centroacinar Cells

    Squamous cells lining the lumen of pancreatic acini, representing the beginning of intercalated ducts.

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    Intercalated Ducts

    Small ducts lined with simple squamous epithelium, connecting the acini to the larger ducts.

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    Interlobular Ducts

    Pancreatic ducts lined with simple cuboidal epithelium, located between the lobules.

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    Interlobar Ducts

    Larger ducts lined with simple columnar epithelium, located between the lobes of the pancreas.

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    Main Pancreatic Duct

    The main duct that carries pancreatic juice to the duodenum, lined with columnar epithelium.

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    Islets of Langerhans

    Clusters of endocrine cells in the pancreas, responsible for secreting hormones like insulin and glucagon.

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    Beta Cells

    The most abundant cells in the islets of Langerhans, responsible for releasing insulin.

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    Alpha Cells

    Cells in the islets of Langerhans that release glucagon, which increases blood sugar levels.

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    Liver Function

    The largest metabolic organ, essential for various functions like nutrient processing, detoxification, and bile production.

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    Study Notes

    Digestive System Overview

    • The digestive tract (alimentary tract) includes the mouth, pharynx, esophagus, stomach, small intestine, large intestine, rectum, and anal canal.

    • The functions of the gastrointestinal tract (GIT) are: the passage (transport) of food; digestion; absorption; and elimination of residues, and absorption of water.

    Structure of the Stomach

    • The stomach is the most dilated part of the GIT, and is divided anatomically into cardia, fundus, body, and pyloric regions.
    • The fundus and body have similar structures.
    • The stomach acts as a food reservoir.
    • Food is acidified and converted into chyme by mechanical and chemical action.
    • The cardia of the stomach contains mucous-secreting glands.

    Stomach Mucosa

    • Gastric pits are small depressions in the stomach lining where the gastric glands open.
    • The epithelium is simple columnar, mucus-secreting.
    • The lamina propria contains the fundic glands.
    • The muscularis mucosa is present.

    Stomach Muscularis

    • The stomach muscularis has inner oblique, middle circular, and outer longitudinal layers.
    • The mechanical action of the muscles is in all directions.

    Pylorus of Stomach

    • The pylorus is the part of the stomach that connects to the duodenum.
    • The pyloric gland characters include: not crowded, highly convoluted, and wider and longer pits.
    • The pyloric sphincter (thick inner circular layer) and the outer longitudinal layer are present.

    Small Intestine

    • The small intestine is the site of terminal food digestion, absorption, and endocrine secretion.
    • It has three parts: duodenum, jejunum, and ileum.
    • The duodenum is the first and shortest part, connecting the stomach to the jejunum and surrounding the head of the pancreas.
    • The jejunum makes up the proximal 2/5 after the duodenum.
    • The ileum is the distal 3/5 of the small intestine.

    Small Intestine Adaptations

    • The small intestine is 6 meters long.
    • Adaptations for absorption include plicae circulares (increasing surface area 3-fold), villi (increasing surface area 10-fold) and microvilli (increasing surface area 20-fold).

    Small Intestine Tissue Layers

    • The mucosa has villi and crypts.
    • The epithelium has simple columnar, goblet, Paneth, enteroendocrine, and caveolate cells.
    • The lamina propria has connective tissue.
    • The muscularis mucosa contains the inner circular and outer longitudinal layers.
    • The submucosa contains Brunner's glands, and lymphatic nodules (Payer's patches).
    • There’s a muscularis externa (inner circular and outer longitudinal layers); and a serosa.

    Large Intestine

    • The large intestine absorbs water and produces mucus for lubrication.
    • Parts of the large intestine include the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, rectum, and anal canal.

    Large Intestine Structure

    • The mucosa has crypts, but no villi.
    • The epithelium has absorptive columnar cells, many goblet cells, enteroendocrine cells, and stem cells.
    • The lamina propria contains lymphatic nodules.
    • The submucosa has no glands.
    • The muscularis externa has an inner circular and an outer longitudinal layer, with only three bundles of the smooth muscle (tenia coli).
    • The serosa is rich in fat cells.

    Glands Associated with the Digestive Tract

    • Salivary glands
    • Pancreas
    • Liver

    Pancreas

    • The pancreas is a mixed gland with exocrine and endocrine parts.
    • The exocrine part secretes pancreatic juice containing enzymes like lipase, trypsin, chymotrypsin, and amylase crucial for digesting fats, proteins, and carbohydrates.
    • The endocrine part secretes hormones like insulin and glucagon regulating blood sugar.

    Liver

    • The liver is a large and important metabolic organ.
    • It receives nutrient-rich blood from the small intestine via the portal vein.
    • It also receives oxygenated blood from the hepatic artery.
    • Functions include exocrine secretion of bile and endocrine secretion of glucose and plasma proteins.
    • Classic liver lobules are hexagonal masses of liver cells (hepatocytes) drained by a central vein, and demarcated by connective tissue.

    Liver Hepatic Structures

    • The hepatocytes are arranged in branching cords or plates (radiating from the central vein).
    • The cords are separated by blood sinusoids.
    • Each cord is formed of two rows of cells enclosing bile canaliculus.
    • The endothelial lining of the blood sinusoids is separated from the hepatocytes by the space of Disse.

    Hepatic Blood Sinusoids

    • Hepatic sinusoids are present between cords of liver cells.
    • They are lined with fenestrated endothelial cells and von Kupffer cells (macrophages) that clean and destroy old or abnormal red blood cells (senile RBCs).

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    Description

    Explore the fascinating digestive system, focusing on the structure and function of the stomach. Learn about the different regions of the stomach, including the cardia, fundus, and body, and how they contribute to digestion and food processing. Understand the importance of gastric pits and the mucosa in digestive functions.

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