Differential Leukocyte Count: Medical Physiology Quiz

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65 Questions

Which type of white blood cell has the ability to 'seek out and destroy' foreign invaders?

Neutrophils

How many WBCs does an adult human have per microliter of blood?

7000-10000

What is the life span of granulocytes in the blood?

4-8 hours

How long do monocytes typically survive in the blood?

10-20 hours

Which type of white blood cell swells to much larger sizes to become tissue macrophages?

Monocytes

What is the average life span of lymphocytes?

Months

Which type of white blood cell are specifically transported to areas of serious infection and inflammation?

Neutrophils

Which type of white blood cell are known as granulocytes?

Neutrophils

Which type of white blood cells provide a rapid and potent defense against infectious agents?

Neutrophils and basophils

What is the main aim of the experiment described in the text?

To measure the percentage of different types of leukocytes in the peripheral blood

How are blood smears prepared for the experiment?

By shaking the film in the air after spreading the blood on a horizontal slide

What is the function of cedar oil in the experiment?

To enhance the visibility of leukocytes under the microscope

Which leukocyte type has a nucleus connected by thin strands of nuclear material?

Neutrophil

What is characteristic of eosinophils?

Their count increases in parasitic infestation and allergic conditions

Which leukocyte type has a nucleus that looks like a telephone receiver?

Eosinophil

What is contained in basophil granules?

Histamine and heparin

Which leukocyte type accounts for 20–40% of all leukocytes?

Large, clear cytoplasm and dark purple nucleus

Neutrophils account for 55–75% of all leukocytes.

True

Eosinophils increase in parasitic infestation and allergic conditions such as bronchial asthma and hay fever.

True

Basophils account for 0–1% of all leukocytes.

True

Lymphocytes produce antibodies.

True

Monocytes become macrophages that defend the body against viruses and bacteria.

True

Chemotaxis refers to the ability of leukocytes to engulf and destroy foreign invaders.

False

Phagocytosis is the process by which leukocytes engulf and destroy foreign invaders.

True

Diapedesis is the passage of leukocytes through intact capillary walls into the surrounding tissue.

True

Leukopenia refers to a high count of leukocytes in the blood.

False

Thrombocytes are also known as white blood cells.

False

Neutrophils are known as granulocytes.

True

Lymphocyte count rises in people with typhoid fever, malaria, infectious mononucleosis, and endocarditis.

True

Neutrophils have a life span of weeks or months.

False

Lymphocytes have a short transit time of 10-20 hours in the blood.

False

Monocytes can live for months unless destroyed during phagocytic functions.

True

Eosinophils are not known for their phagocytic functions.

False

Basophils provide a rapid and potent defense against infectious agents.

False

Granulocytes have life spans of weeks or months in the blood.

False

White blood cells are also known as erythrocytes.

False

The adult human being has about 2,000-3,000 WBCs per microliter of blood.

False

Lymphocytes have a life span of only 4-5 days in tissues.

False

Granulocytes and monocytes have the special ability to seek out and destroy foreign invaders.

True

Agranulocytes include neutrophils and eosinophils.

False

The granulocytes and monocytes have a short transit time of 10-20 hours in the blood.

False

What is the life span of granulocytes after being released from the bone marrow?

4-8 hours circulating in the blood and another 4-5 days in tissues

How long can monocytes typically survive in the blood?

10-20 hours

What is the concentration of white blood cells in the adult human being per microliter of blood?

7000-10,000

What is the function of lymphocytes?

Produce antibodies

What is characteristic of eosinophils?

Increase in parasitic infestation and allergic conditions

What is the main aim of the experiment described in the text?

Leukocyte count

What is the life span of lymphocytes?

Weeks or months

What is the life span of monocytes in tissues?

Months

What type of white blood cells specifically transported to areas of serious infection and inflammation?

Granulocytes and monocytes

What is the function of cedar oil in the experiment?

Preparation of blood smears

What is the characteristic of the nucleus of monocytes?

Connected by thin strands of nuclear material

What is contained in basophil granules?

Histamine and heparin

What is the procedure for making a blood smear?

Put a drop of blood on one end of the first slide and spread it using a second slide. Then allow the film to dry and stain it with leishman’s stain.

What is the aim of determining the percentage of different types of leucocytes in the peripheral blood?

To diagnose certain diseases where certain types of leucocytes may increase or decrease.

What is the function of cedar oil in the experiment?

To recognize the cells using objective lens power.

What is characteristic of neutrophils?

Multilobed nucleus connected by thin strands of nuclear material and tiny, light staining granules.

What is the characteristic of eosinophils?

Bilobed nucleus which looks like a telephone receiver and large, pinkish to red granules.

What is the characteristic of basophils?

Nucleus is bilobed, masked by numerous, deeply stained blue to purple granules.

What is characteristic of lymphocytes?

Very large nucleus for the size of the cell, stains dark purple, and small, clear cytoplasm.

What is characteristic of monocytes?

Largest of the leucocytes, kidney-shaped nucleus, and abundant, light blue cytoplasm.

What is the term for a low count of lymphocytes?

Lymphocytopenia.

What is the term for a high count of neutrophils?

Neutrophilia.

What is the term for a high count of monocytes?

Monocytosis.

What is the term for the process by which leukocytes engulf and destroy foreign invaders?

Phagocytosis.

Study Notes

White Blood Cells

  • Granulocytes and monocytes have the ability to 'seek out and destroy' foreign invaders.
  • An adult human has about 4,500-11,000 WBCs per microliter of blood.

Granulocytes

  • Include neutrophils, eosinophils, and basophils.
  • Neutrophils account for 55-75% of all leukocytes.
  • Eosinophils increase in parasitic infestation and allergic conditions such as bronchial asthma and hay fever.
  • Basophils account for 0-1% of all leukocytes.
  • Have a life span of weeks or months in the blood.

Monocytes

  • Can live for months unless destroyed during phagocytic functions.
  • Become macrophages that defend the body against viruses and bacteria.
  • Are typically transported to areas of serious infection and inflammation.
  • Have a nucleus connected by thin strands of nuclear material.

Lymphocytes

  • Produce antibodies.
  • Have a life span of 4-5 days in tissues.
  • Account for 20-40% of all leukocytes.
  • Count rises in people with typhoid fever, malaria, infectious mononucleosis, and endocarditis.

Phagocytosis and Chemotaxis

  • Phagocytosis is the process by which leukocytes engulf and destroy foreign invaders.
  • Chemotaxis is the ability of leukocytes to move towards foreign invaders.

Blood Smear Preparation and Experiment

  • Blood smears are prepared by spreading a thin layer of blood on a glass slide.
  • Cedar oil is used to fix the blood smear.
  • The main aim of the experiment is to determine the percentage of different types of leukocytes in the peripheral blood.

Leukocyte Characteristics

  • Eosinophils are characterized by their bilobed nucleus and acidophilic granules.
  • Basophils are characterized by their small size and sparse, darkly staining granules.
  • Lymphocytes are characterized by their large nucleus and small amount of cytoplasm.
  • Monocytes are characterized by their kidney-shaped nucleus connected by thin strands of nuclear material.

Leukopenia and Leukocytosis

  • Leukopenia refers to a low count of leukocytes in the blood.
  • Leukocytosis refers to a high count of leukocytes in the blood.

Test your knowledge about leukocytes (white blood cells) and their role in the body's protective system. Learn about the general characteristics and types of white blood cells in this quiz.

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