10 Questions
What is the primary difference between acute and chronic DIC?
Acute DIC is characterized by hemorrhage, while chronic DIC is characterized by thrombosis.
Which group of patients is more likely to develop chronic DIC?
Patients with solid tumors
In which percentage of patients with sepsis does DIC occur?
30-50%
What are the typical physical findings in patients with acute DIC?
Petechiae on the soft palate and extremities, ecchymosis at venipuncture sites
What is the estimated occurrence of DIC in all hospitalized patients?
1%
Which of the following is NOT a feature of managing DIC?
Administer heparin immediately
What is the primary focus of treatment for DIC?
Addressing the underlying disorder
What causes the clinical manifestations in patients with TTP?
Unusually large multimers of von Willebrand factor (vWF)
What characterizes thrombotic thrombocytopenic purpura (TTP) as a hematological emergency?
Clotting in small blood vessels, low platelet count, and end organ damage
What is responsible for the breakdown of ultralarge vWF multimers in acquired TTP?
An antibody inhibitor
Test your knowledge on the differences between acute and chronic disseminated intravascular coagulation (DIC) and the mechanisms involved in each.
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