Introduction to Hematology History Quiz
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Questions and Answers

Who is described as the 'Father of Hematology' and the inventor of the microscope for the microscopic size of RBC?

  • Anton van Leeuwenhoek (correct)
  • Giulio Bizzozero
  • Athanasius Kircher
  • James Homer Wright

    • What is the approximate total volume of blood in an average male?

  • 6-7 L
  • 3-4 L
  • 2-3 L
  • 5-6 L (correct)

    • Which component of blood is approximately 3.5-4.5 times thicker than water?

  • Buffy coat
  • Erythrocyte (correct)
  • Formed elements
  • Plasma

    • What is the function of the uppermost layer of the Buffy coat?

    <p>Contains platelets</p> Signup and view all the answers

    In which year did Athanasius Kircher describe a worm in the blood?

    <p>1657</p> Signup and view all the answers

    What does 'in vivo' research refer to?

    <p>Research done on a living organism</p> Signup and view all the answers

    What is the specific gravity of arterial (oxygenated) blood?

    <p>1.025 – 1.029</p> Signup and view all the answers

    What is the mode of action of ethylenediaminetetraacetic acid (EDTA) as an anticoagulant?

    <p>It removes ionized calcium (Ca2+) through chelation</p> Signup and view all the answers

    Which anticoagulant is the choice for most chemistry tests?

    <p>Heparin</p> Signup and view all the answers

    What is the ratio of blood to anticoagulant for the Standard Westergren (black top) method?

    <p>4:1</p> Signup and view all the answers

    Which anticoagulant is used for preserving glucose and as an inhibitor of glycolysis?

    <p>Sodium fluoride</p> Signup and view all the answers

    What is the action of sodium fluoride as an anticoagulant?

    <p>Inhibitor of glycolysis</p> Signup and view all the answers

    What did Giulio Bizzozero describe in the 1800s?

    <p>Function and size of platelets</p> Signup and view all the answers

    What is the approximate total volume of blood in an average female?

    <p>4 to 5 liters</p> Signup and view all the answers

    Who is considered the 'Father of Hematology' and the inventor of the microscope for the microscopic size of RBC?

    <p>Anton van Leeuwenhoek</p> Signup and view all the answers

    What is the percentage composition of the solid portion in blood?

    <p>45%</p> Signup and view all the answers

    What is the approximate pH range of blood?

    <p>7.35-7.45</p> Signup and view all the answers

    What does 'in vivo' research refer to?

    <p>Research done on a living organism</p> Signup and view all the answers

    What is the specific gravity range for serum?

    <p>1.024-1.028</p> Signup and view all the answers

    What is the mode of action of EDTA as an anticoagulant?

    <p>Removal of ionized calcium (Ca2+)</p> Signup and view all the answers

    Which anticoagulant is the choice for most chemistry tests?

    <p>Heparin</p> Signup and view all the answers

    What is the action of sodium fluoride as an anticoagulant?

    <p>Inhibitor of glycolysis</p> Signup and view all the answers

    What is the function of the anticoagulant EDTA?

    <p>Chelation of calcium</p> Signup and view all the answers

    Which anticoagulant is recommended for the Standard Westergren (black top) method?

    <p>Oxalate</p> Signup and view all the answers

    What is the optimum concentration of heparin for most chemistry tests?

    <p>15 to 20 U/ml of blood</p> Signup and view all the answers

    Which anticoagulant is used in a concentration of $3.2%$ or $0.109M$ and preserves factor V and VIII?

    <p>Sodium citrate</p> Signup and view all the answers

    What is the ratio of blood to anticoagulant for the Standard Westergren (black top) method?

    <p>4:1</p> Signup and view all the answers

    Study Notes

    Blood and Hematology

    • Antonie Van Leeuwenhoek is described as the 'Father of Hematology' and the inventor of the microscope for the microscopic size of RBC.

    Blood Composition

    • The approximate total volume of blood in an average male is 5-6 liters.
    • The approximate total volume of blood in an average female is 4-5 liters.
    • The solid portion of blood makes up around 45% of the total volume.

    Blood Properties

    • The specific gravity of arterial (oxygenated) blood is 1.056-1.066.
    • The specific gravity range for serum is 1.018-1.022.
    • The approximate pH range of blood is 7.35-7.45.

    Anticoagulants

    • The component of blood that is approximately 3.5-4.5 times thicker than water is plasma.
    • Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant that works by binding to calcium ions, preventing blood clotting.
    • EDTA is the choice for most chemistry tests.
    • The ratio of blood to anticoagulant for the Standard Westergren (black top) method is 4:1.
    • Sodium fluoride is an anticoagulant that inhibits glycolysis and preserves glucose.
    • Sodium fluoride is used as an anticoagulant in a concentration of 2-3%.
    • Heparin is an anticoagulant that works by activating antithrombin, and its optimum concentration for most chemistry tests is 10-15 units/mL.
    • Citrate is an anticoagulant used in a concentration of 3.2% or 0.109M and preserves factor V and VIII.

    History of Hematology

    • Athanasius Kircher described a worm in the blood in 1658.
    • Giulio Bizzozero described platelets in the 1800s.

    Research

    • 'In vivo' research refers to experiments or observations conducted within living organisms, such as animals or humans.

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    Description

    Test your knowledge on the history of hematology with this quiz covering important figures and their contributions, such as Athanasius Kircher, Anton van Leeuwenhoek, and Giulio Bizzozero. Explore the development of understanding of blood, red blood cells, and platelets.

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