Diabetes Overview: Insulin and Types
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Questions and Answers

What is the primary function of insulin in relation to glucose?

  • Promotes glucose release from fat
  • Stimulates glucose transportation and storage (correct)
  • Inhibits glucose production in muscle
  • Increases the breakdown of glucose
  • What condition occurs when Type I diabetes is diagnosed?

  • Chronic kidney disease
  • Diabetic ketoacidosis (DKA) (correct)
  • Sudden hyperglycemia without symptoms
  • Gradual weight gain and fatigue
  • Which of the following is a common clinical manifestation of Type I diabetes?

  • Frequent hunger without weight loss
  • Stable weight with no thirst
  • Increased skin elasticity
  • Frequent urination, thirst, and hunger (correct)
  • Which of the following statements about the risk factors for Type 1 diabetes is true?

    <p>It requires a genetic predisposition combined with environmental factors. (B)</p> Signup and view all the answers

    What hormone's production is compromised in Type I diabetes?

    <p>Insulin from beta cells (D)</p> Signup and view all the answers

    Type II diabetes initially affects which of the following?

    <p>Insulin sensitivity and beta cell function (A)</p> Signup and view all the answers

    Which of the following symptoms is NOT associated with the clinical presentation of diabetes?

    <p>Dizziness upon standing (C)</p> Signup and view all the answers

    What initial treatment is typically advised for managing Type II diabetes?

    <p>Strict dietary restrictions and regular exercise (C)</p> Signup and view all the answers

    What is considered a random glucose level indicating diagnosis of diabetes?

    <p>11.1 mmol L (B)</p> Signup and view all the answers

    What is a necessary adjustment for a patient using an insulin pump when skipping a meal?

    <p>Hold the insulin dose (B)</p> Signup and view all the answers

    Which type of insulin has an onset of action lasting about 5 to 15 minutes?

    <p>Rapid-acting insulin (A)</p> Signup and view all the answers

    Which of the following symptoms is NOT associated with hypoglycemia?

    <p>Polyuria (B)</p> Signup and view all the answers

    What is the purpose of dietary management in diabetes care?

    <p>To achieve and maintain reasonable weight (B)</p> Signup and view all the answers

    What should a nurse advise a patient if ketones are present in their urine?

    <p>To avoid any form of exercise (A)</p> Signup and view all the answers

    What should be administered for the immediate management of hypoglycemia?

    <p>15 grams of fast-acting carbohydrates (D)</p> Signup and view all the answers

    How long does intermediate-acting insulin typically last?

    <p>Up to 24 hours (A)</p> Signup and view all the answers

    What metabolic condition results from inadequate amounts of insulin?

    <p>Diabetic Ketoacidosis (C)</p> Signup and view all the answers

    Which of these symptoms is indicative of the CNS effects of severe hypoglycemia?

    <p>Severe disorientation (B)</p> Signup and view all the answers

    What effect does fibre have on glucose absorption?

    <p>It slows down glucose absorption (C)</p> Signup and view all the answers

    What is the recommended carbohydrate intake before moderate exercise in cases of hypoglycemia?

    <p>15g (B)</p> Signup and view all the answers

    How should insulin delivery be structured for a patient engaging in daily exercise?

    <p>Adjust insulin based on meals and exercise (B)</p> Signup and view all the answers

    What is the significance of an AIC level of 6.5 in diabetes management?

    <p>It confirms a diabetes diagnosis (A)</p> Signup and view all the answers

    What is the pH level commonly associated with metabolic acidosis in diabetic ketoacidosis?

    <p>Below 7.0 (A)</p> Signup and view all the answers

    What should be included in a snack recommended for someone experiencing hypoglycemia?

    <p>Fast-acting carbohydrates and protein (D)</p> Signup and view all the answers

    What physiological effects are associated with Ketoacidosis?

    <p>Low PCO2 reflecting respiratory compensation (A), High serum glucose levels (B)</p> Signup and view all the answers

    Which of the following is a recommended intervention for managing DKA?

    <p>Monitor renal function and electrolyte levels (B)</p> Signup and view all the answers

    What is a key characteristic of Hyperglycemic Hyperosmolar Syndrome (HHS)?

    <p>Presence of osmotic diuresis (A)</p> Signup and view all the answers

    Which statement about the blood glucose levels in DKA is accurate?

    <p>Blood glucose levels can range significantly (D)</p> Signup and view all the answers

    What should be monitored closely during HHS treatment to ensure effective management?

    <p>Fluid intake and blood pressure (A)</p> Signup and view all the answers

    How can DKA be prevented in patients with Type I diabetes?

    <p>By ensuring routine testing of blood sugar levels (A)</p> Signup and view all the answers

    What is a common complication of severe hyperglycemia in HHS?

    <p>Dehydration and concentrated electrolytes (D)</p> Signup and view all the answers

    Which symptom is typically not associated with DKA?

    <p>Electrolyte retention (B)</p> Signup and view all the answers

    Flashcards

    Insulin function

    Insulin transports glucose for energy and stimulates glycogen storage in liver and muscle. It enhances fat storage and accelerates amino acid transport, and inhibits glucose/protein breakdown of stored fat.

    Type 1 Diabetes

    An autoimmune disease where the beta cells in the pancreas are destroyed, resulting in little or no insulin production.

    Type 1 Diabetes Symptoms (3P)

    Polyuria (frequent urination), Polydipsia (increased thirst), and Polyphagia (increased hunger) are common symptoms.

    Type 2 Diabetes

    A condition where the body's cells are resistant to insulin or the pancreas doesn't produce enough insulin.

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    Type 2 Diabetes Treatment

    Initially managed with diet and exercise, this is a form of diabetes characterized by a gradual onset.

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    Type 1 Diabetes Risk Factors

    Type 1 diabetes is not inherited but has a genetic predisposition, combined with immunologic and possibly environmental/viral factors.

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    Type 2 Diabetes Risk Factors

    Factors include family history of diabetes, obesity, older age than 45, and certain ethnicities.

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    Type 1 Diabetes Clinical Manifestations

    Sudden weight loss, nausea, stomach pain, irritability, skin wounds, vaginal infections, and blurred vision are potential symptoms.

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    Hypoglycemia Symptoms

    Low blood glucose levels, causing symptoms like tremors, sweating, palpitations, nervousness, and hunger. More severe symptoms include confusion, slurred speech, disorientation, seizures, and loss of consciousness.

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    Hypoglycemia Management

    Treat low blood glucose (hypoglycemia) by giving 15 grams of fast-acting carbohydrates, such as glucose tablets, soda, juice, candies, or sugar/honey; followed with a snack containing protein and starch to prevent a relapse.

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    Diabetic Ketoacidosis (DKA) Features

    A serious complication of diabetes where inadequate insulin causes the abnormal metabolism of carbohydrates, fats, and proteins. Features include hyperglycemia, dehydration, electrolyte imbalance, and acidosis (a drop in blood pH).

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    Insulin Pump

    A device that delivers insulin continuously, mimicking the normal release from the pancreas, with flexible mealtimes and exercise.

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    Insulin Adjustment for Meals

    Insulin doses can be adjusted to match meals; If skipping a meal, insulin dose needs to be decreased.

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    Pancreatic Function Mimicking

    Insulin pump delivery system mimics the pancreas to control blood sugar levels.

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    Initial Diabetes Management

    It is recommended to manage diabetes one year before getting an insulin pump.

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    Hold Insulin

    Hold insulin administration if patient takes rapid-acting insulin and skips a meal.

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    Diabetic Ketoacidosis (DKA)

    A serious complication of diabetes where the body produces excess ketones due to a lack of insulin. This leads to acidosis and potentially life-threatening complications.

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    DKA cause

    DKA is caused by insufficient insulin, leading to the breakdown of fat for energy, producing ketones.

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    DKA symptoms

    Symptoms of DKA include high blood glucose, ketones in the blood, and Kussmaul respirations.

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    DKA Treatment

    DKA treatment involves rehydration, insulin administration, and monitoring of blood glucose and electrolytes.

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    Hyperglycemic Hyperosmolar Syndrome (HHS)

    A serious complication of diabetes characterized by extremely high blood sugar without significant ketoacidosis.

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    HHS cause

    HHS is caused by a severe lack of insulin, leading to osmotic diuresis and severe dehydration.

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    HHS symptoms

    HHS symptoms include severe dehydration, high blood glucose, and neurological signs.

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    HHS Treatment

    HHS treatment primarily involves rehydration and insulin administration.

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    Diabetes Diagnostic Finding

    A blood test that indicates high blood sugar levels, such as an AIC above 6.5, or a random glucose test exceeding 11.1 mmol/L.

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    Oral Glucose Tolerance Test

    A test measuring blood glucose levels after consuming 75g of glucose.

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    Diabetes Dietary Management

    Meeting energy needs, achieving/maintaining a healthy weight, preventing/managing serum lipids, and understanding the glycemic index of foods to manage blood sugar.

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    Diabetes Exercise

    Exercise can be a risk for hypoglycemia if ketones are present. Consume 15g of carbs before moderate exercise when ketones levels are not present.

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    Diabetes Insulin Therapy Onset Times

    Rapid-acting insulin, onset 5-15 mins; short-acting, onset 30-60 mins; intermediate, onset 24 hours; very long-acting, onset 6 hours.

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    Normal Blood Glucose Range

    4.0 mmol/L to 7.0 mmol/L

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    Glycemic Index

    A measure of how much a food raises blood glucose levels.

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    Ketones and Exercise

    If ketones are present in the blood, do NOT exercise. Eat 15g of carbs before moderate exercise if ketones are not present.

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    Study Notes

    Diabetes Functions of Insulin

    • Insulin transports and metabolizes glucose for energy
    • Stimulates glucose storage in liver and muscle as glycogen
    • Signals the liver to stop releasing glucose
    • Enhances storage of fat
    • Accelerates amino acid transport
    • Inhibits the breakdown of glucose, protein, and fat

    Type 1 Diabetes

    • Beta cells in the pancreas are destroyed by an autoimmune process
    • The body produces little to no insulin
    • Diabetic Ketoacidosis (DKA) sets in when diagnosis occurs
    • Symptoms include polyuria, polydipsia, and polyphagia (frequent urination, thirst, and hunger)

    Type 2 Diabetes

    • Impaired beta cell function leading to reduced insulin production
    • Initially managed with diet and exercise
    • Clinical manifestations include fatigue, irritability, skin wounds, vaginal infections, blurred vision, and sudden weight loss, nausea, stomach pain

    Diagnostic Findings

    • Glycated hemoglobin (A1C) of 6.5% or more
    • Random glucose exceeding 11mmol/L
    • Oral glucose tolerance test exceeding 7.0mmol/L
    • Fasting plasma glucose above 7.0mmol/L

    Dietary Management

    • Meet energy needs
    • Achieve and maintain a reasonable weight
    • Prevent fluctuations of blood glucose levels
    • Monitor serum lipids

    Glycemic Index

    • How much food raises blood glucose
    • Fiber slows absorption of glucose in fruit, starchy foods, and protein don't spike the glycemic index

    Insulin Therapy: Onset

    • Rapid-acting (5-15mins)
    • Short-acting (30-60mins)
    • Intermediate (2-4hrs) - NPH
    • Very long-acting (1-6hrs) - continuous

    Insulin Therapy: Two or more daily injections

    • May need to adjust daily exercise & diet regime, premixed cannot be adjusted
    • Test blood more often
    • Adjust doses for meals and exercise
    • More flexible doses
    • Insulin pump
    • Bolus occurs at mealtimes, must manage diabetes for 1 year, and then can get a pump

    Hypoglycemia

    • Low blood glucose (<3.7mmol/L)
    • Symptoms include sweating, tremors, tachycardia, palpitations, nervousness, and hunger
    • CNS symptoms include headache, lightheadedness, confusion, slurred speech, disorientation, seizures, difficulty arousing from sleep, and loss of consciousness
    • Management involves giving 15g of fast-acting carb, 125ml of juice/soda, 3 hard candies, 15ml of sugar

    Diabetic Ketoacidosis (DKA)

    • Inadequate amount of insulin
    • Abnormal metabolism of carb, fat, and protein
    • Features include hyperglycemia, dehydration, and electrolyte loss, acidosis with a PH value <7.5.

    Risk Factors

    • Type 1: Inherited, but likely genetic predisposition combined with environmental factors (possibly viral)
    • Type 2: Family history of diabetes, ethnicity, age over 45, obesity, hypertension, gestational diabetes. Babies weighing over 9.165 lbs.

    Prevention of DKA

    • Follow "sick-day rules" (take insulin as usual, test blood glucose every 3-4 hrs, may need to take supplemental doses of regular insulin, cannot skip meals.)
    • Hyperglycemic Hyperosmolar Syndrome (HHS): lack of effective or absent insulin, hyperglycemia causes osmotic diuresis with loss of water and electrolytes.
    • Management involves hydration, insulin administration, monitoring fluid and electrolytes

    Long-term Complications of Diabetes

    • Macrovascular changes (atherosclerotic changes, coronary artery disease, ex: ulcers, strokes, and MI)
    • Microvascular damage to eyes and kidneys
    • Neuropathic changes (peripheral neuropathy, autonomic neuropathies, and sexual dysfunction)

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    Diabetes Notes PDF

    Description

    Explore the essential functions of insulin and its role in diabetes management. This quiz covers the differences between Type 1 and Type 2 diabetes, their symptoms, and key diagnostic findings. Test your knowledge on how insulin impacts glucose metabolism and storage in the body.

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