Diabetes Mellitus
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Questions and Answers

Which of the following is a chronic complication of diabetes mellitus?

  • Peripheral vascular disease (correct)
  • DKA
  • Polydipsia
  • Weight loss

Which diagnostic test reflects the average blood glucose over the prior 3 months?

  • 2-hour oral glucose tolerance test
  • Random plasma glucose
  • Fasting plasma glucose
  • HbA1c (correct)

Which of the following is a manifestation of diabetes mellitus?

  • Hyaline arteriolosclerosis
  • GERD
  • Sorbitol accumulation
  • Polyuria (correct)

Which of the following is a chronic complication of diabetes mellitus?

<p>Retinopathy (A)</p> Signup and view all the answers

Which of the following is a manifestation of diabetes mellitus?

<p>Polyuria (A)</p> Signup and view all the answers

Which diagnostic test reflects the average blood glucose over the prior 3 months?

<p>HbA1c (D)</p> Signup and view all the answers

What is the most common cause of death in patients with diabetes mellitus?

<p>Myocardial infarction (D)</p> Signup and view all the answers

Which of the following can be caused by unopposed secretion of GH and epinephrine?

<p>Weight loss (A)</p> Signup and view all the answers

Which organ is affected by osmotic damage due to sorbitol accumulation in diabetes mellitus?

<p>Eye (C)</p> Signup and view all the answers

Which type of diabetes mellitus is associated with diabetic ketoacidosis (DKA)?

<p>Type 1 (C)</p> Signup and view all the answers

Which diagnostic test requires fasting for more than 8 hours?

<p>Fasting plasma glucose (A)</p> Signup and view all the answers

Which of the following is a chronic complication of diabetes mellitus affecting the peripheral blood vessels?

<p>Peripheral vascular disease (D)</p> Signup and view all the answers

Which type of diabetes is characterized by autoimmune T-cell-mediated destruction of beta cells?

<p>Type 1 (B)</p> Signup and view all the answers

Which type of diabetes is associated with resistance to insulin and progressive pancreatic beta-cell failure?

<p>Type 2 (B)</p> Signup and view all the answers

Which type of diabetes requires insulin in its treatment?

<p>Type 1 (A)</p> Signup and view all the answers

Which type of diabetes is more commonly associated with obesity?

<p>Type 2 (A)</p> Signup and view all the answers

Which type of diabetes has a relatively weak genetic predisposition?

<p>Type 1 (C)</p> Signup and view all the answers

Which type of diabetes is associated with the HLA system, specifically HLA-DR4 and -DR3?

<p>Type 1 (B)</p> Signup and view all the answers

Which type of diabetes is associated with severe glucose intolerance?

<p>Type 1 (D)</p> Signup and view all the answers

Which type of diabetes is characterized by high insulin sensitivity?

<p>Type 1 (C)</p> Signup and view all the answers

Which type of diabetes is commonly associated with diabetic ketoacidosis (DKA)?

<p>Type 1 (C)</p> Signup and view all the answers

Which of the following electrolyte imbalances is commonly seen in patients with hyperglycemia and osmotic diuresis?

<p>Hypokalemia (B)</p> Signup and view all the answers

What is the most common cause of death in patients with untreated hyperglycemia and osmotic diuresis?

<p>Cardiac arrhythmias (C)</p> Signup and view all the answers

Which of the following treatments is recommended to replete intracellular potassium stores in patients with hyperglycemia and osmotic diuresis?

<p>K+ (A)</p> Signup and view all the answers

What is the serum osmolality level commonly observed in patients with hyperglycemia and osmotic diuresis?

<blockquote> <p>320 mOsm/kg (B)</p> </blockquote> Signup and view all the answers

Which of the following is a potential complication of untreated hyperglycemia and osmotic diuresis that can result in coma and death?

<p>Cerebral edema (A)</p> Signup and view all the answers

What is the typical serum potassium level in patients with hyperglycemia and osmotic diuresis?

<p>Normal (B)</p> Signup and view all the answers

Which of the following is NOT a characteristic of hyperglycemia and osmotic diuresis?

<p>Ketones in urine (C)</p> Signup and view all the answers

Which of the following is a potential complication of untreated hyperglycemia and osmotic diuresis that can result in coma and death?

<p>Cerebral edema (A)</p> Signup and view all the answers

Which of the following is a recommended treatment for hyperglycemia and osmotic diuresis?

<p>IV fluids (D)</p> Signup and view all the answers

Which of the following is a symptom of hypoglycemia in diabetes mellitus?

<p>Rapid heartbeat (B)</p> Signup and view all the answers

What is the treatment for hypoglycemia in diabetes mellitus?

<p>Simple carbohydrates (B)</p> Signup and view all the answers

What is the most common cause of Cushing syndrome?

<p>Excessive cortisol production (C)</p> Signup and view all the answers

What are the clinical findings associated with Cushing syndrome?

<p>Moon facies (A)</p> Signup and view all the answers

What is the main cause of endogenous Cushing syndrome?

<p>ACTH-secreting pituitary adenoma (D)</p> Signup and view all the answers

What is the treatment for Cushing syndrome?

<p>Surgical removal of adrenal glands (D)</p> Signup and view all the answers

What is a characteristic finding in patients with Cushing syndrome?

<p>Easy bruising (A)</p> Signup and view all the answers

What is the most common cause of death in patients with Cushing syndrome?

<p>Metabolic complications (D)</p> Signup and view all the answers

What type of diabetes is associated with severe glucose intolerance?

<p>Type 1 diabetes (B)</p> Signup and view all the answers

Which diagnostic test requires fasting for more than 8 hours?

<p>Fasting plasma glucose test (C)</p> Signup and view all the answers

Which of the following is a symptom of adrenal insufficiency?

<p>Muscle weakness (D)</p> Signup and view all the answers

What is the most common cause of primary adrenal insufficiency in high-income countries?

<p>Autoimmune adrenalitis (C)</p> Signup and view all the answers

Which of the following is a characteristic finding in Addison disease?

<p>Hyperpigmentation (A)</p> Signup and view all the answers

What is the treatment for adrenal insufficiency?

<p>Glucocorticoid replacement (D)</p> Signup and view all the answers

Which of the following is a cause of tertiary adrenal insufficiency?

<p>Abrupt cessation of chronic glucocorticoid therapy (C)</p> Signup and view all the answers

What is the most common cause of Nelson syndrome?

<p>Pituitary pathologies (A)</p> Signup and view all the answers

Which of the following is NOT a symptom of adrenal insufficiency?

<p>Increased blood pressure (C)</p> Signup and view all the answers

What is the treatment for primary adrenal insufficiency?

<p>Mineralocorticoid replacement (C)</p> Signup and view all the answers

Which of the following is a common precipitating factor for acute adrenal insufficiency?

<p>Infection (B)</p> Signup and view all the answers

What is a possible presenting symptom of acute adrenal insufficiency?

<p>Confusion (C)</p> Signup and view all the answers

Which syndrome is characterized by bilateral adrenal hemorrhage in the setting of sepsis?

<p>Waterhouse-Friderichsen syndrome (A)</p> Signup and view all the answers

What is the medical term for acute adrenal (addisonian) crisis?

<p>Adrenal fatigue (B)</p> Signup and view all the answers

Which organ is affected by acute adrenal insufficiency?

<p>Adrenal glands (B)</p> Signup and view all the answers

What is a possible symptom of acute adrenal insufficiency?

<p>Hypoglycemia (D)</p> Signup and view all the answers

What is the most common cause of acute adrenal insufficiency?

<p>Autoimmune destruction of the adrenal glands (B)</p> Signup and view all the answers

What is a possible symptom of acute adrenal insufficiency?

<p>Hypoglycemia (C)</p> Signup and view all the answers

Which term is used to describe acute adrenal insufficiency?

<p>Adrenal crisis (C)</p> Signup and view all the answers

What can precipitate acute adrenal insufficiency?

<p>Acute stressors (C)</p> Signup and view all the answers

Which symptom may present in a patient with acute adrenal insufficiency?

<p>Acute abdominal pain (B)</p> Signup and view all the answers

What is Waterhouse-Friderichsen syndrome?

<p>Bilateral adrenal hemorrhage in the setting of sepsis (D)</p> Signup and view all the answers

What is the cause of Waterhouse-Friderichsen syndrome?

<p>Sepsis (C)</p> Signup and view all the answers

What is the typical clinical presentation of Waterhouse-Friderichsen syndrome?

<p>Shock (A)</p> Signup and view all the answers

What is the main cause of primary adrenal insufficiency in high-income countries?

<p>Autoimmune destruction (A)</p> Signup and view all the answers

What is the treatment for acute adrenal insufficiency?

<p>Glucocorticoid therapy (D)</p> Signup and view all the answers

Which of the following is a symptom of primary adrenal insufficiency?

<p>Hyperpigmentation (A)</p> Signup and view all the answers

What is the most common cause of primary adrenal insufficiency in high-income countries?

<p>Autoimmune adrenalitis (C)</p> Signup and view all the answers

Which of the following is a symptom of acute adrenal insufficiency?

<p>Orthostatic hypotension (C)</p> Signup and view all the answers

What is the most common cause of Nelson syndrome?

<p>Enlargement of pre-existing ACTH-secreting pituitary adenoma (D)</p> Signup and view all the answers

Which of the following is a potential complication of untreated hyperglycemia and osmotic diuresis?

<p>Coma (C)</p> Signup and view all the answers

What is a characteristic finding in patients with Cushing syndrome?

<p>Hyperpigmentation (A)</p> Signup and view all the answers

What is the treatment for adrenal insufficiency?

<p>Glucocorticoid replacement (A)</p> Signup and view all the answers

What is the main cause of endogenous Cushing syndrome?

<p>Pituitary pathologies (A)</p> Signup and view all the answers

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