Diabetes and Hormone Disorders Quiz

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Questions and Answers

What is the primary cause of the condition detailed in the description?

  • Liver dysfunction
  • Overproduction of insulin
  • Kidney failure
  • Pancreatic cell damage or autoimmune disease (correct)

Which of the following is NOT a typical sign or symptom of the condition described?

  • Bradycardia (correct)
  • Polydipsia
  • Polyphagia
  • Polyuria

What is the most appropriate treatment for the condition described?

  • Diet and exercise alone
  • Oral hypoglycemic medications only
  • Thyroid hormone replacement therapy
  • Insulin injections and blood glucose monitoring (correct)

What does the term 'polyuria' refer to within the context of the condition described?

<p>Frequent urination (C)</p> Signup and view all the answers

What is the role of LH in females?

<p>Triggers ovulation and estrogen release (C)</p> Signup and view all the answers

What condition is characterized by deficient aldosterone and severe dehydration?

<p>Addison's disease (D)</p> Signup and view all the answers

Which hormone primarily stimulates the liver to increase blood glucose levels?

<p>Glucagon (C)</p> Signup and view all the answers

What is the primary function of aldosterone?

<p>Promote sodium reabsorption and water retention (B)</p> Signup and view all the answers

Which gland is responsible for synthesizing neurohormones like oxytocin and ADH?

<p>Hypothalamus (A)</p> Signup and view all the answers

What is the consequence of hypersecretion of insulin?

<p>Decreased blood glucose levels (D)</p> Signup and view all the answers

What is the main effect of decreased aldosterone levels?

<p>Decreased sodium and water retention (A)</p> Signup and view all the answers

Which statement accurately describes diabetes insipidus?

<p>It leads to excessive thirst and urination. (A)</p> Signup and view all the answers

What hormone is secreted when blood glucose levels increase and primarily lowers blood glucose levels?

<p>Insulin (D)</p> Signup and view all the answers

Which hormone functions to stimulate labor and milk ejection from the breast?

<p>Oxytocin (A)</p> Signup and view all the answers

Which gland is described as having two distinct portions, anterior pituitary and posterior pituitary?

<p>Pituitary Gland (C)</p> Signup and view all the answers

Which hormone primarily acts on the kidneys to reduce water loss and help maintain blood pressure?

<p>Anti-diuretic hormone (ADH) (D)</p> Signup and view all the answers

Cushing's syndrome can be a result of what hormonal imbalance?

<p>Prolonged high cortisol levels (D)</p> Signup and view all the answers

Which hormone promotes gluconeogenesis and is released in response to stress and ACTH?

<p>Cortisol (D)</p> Signup and view all the answers

Which hormone decreases blood calcium levels by increasing bone uptake and kidney excretion?

<p>Calcitonin (A)</p> Signup and view all the answers

What condition results from hyper-secretion of GH in adults, particularly affecting skeletal growth?

<p>Acromegaly (B)</p> Signup and view all the answers

Which hormone is known to aid in fat and carbohydrate metabolism and is produced by the anterior pituitary?

<p>Growth Hormone (GH) (A)</p> Signup and view all the answers

Which condition is characterized by a low metabolic rate and cold sensitivity due to thyroid dysfunction?

<p>Myxedema (D)</p> Signup and view all the answers

The mineralocorticoids are primarily responsible for regulating what in the body?

<p>Blood volume and blood pressure (D)</p> Signup and view all the answers

What role does glucagon play in blood glucose regulation?

<p>Stimulates gluconeogenesis (B)</p> Signup and view all the answers

Which part of the adrenal gland is responsible for producing catecholamines in response to stress?

<p>Adrenal Medulla (B)</p> Signup and view all the answers

What condition might result from a tumor in the pituitary or adrenal glands leading to hyper-secretion of hormones?

<p>Cushing's syndrome (A)</p> Signup and view all the answers

Flashcards

Type 1 Diabetes

A condition where the pancreas is damaged, often due to an autoimmune reaction, leading to insufficient insulin production.

Insulin

This hormone regulates blood sugar levels by allowing glucose to enter cells.

Polyuria

Frequent urination, often a symptom of diabetes.

Polydipsia

Excessive thirst, commonly associated with diabetes.

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Polyphagia

Increased hunger, a symptom of diabetes due to inadequate glucose utilization.

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Antidiuretic Hormone (ADH)

Pituitary gland hormone that controls water balance and reabsorption by the kidneys.

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Cushing's Syndrome

A condition caused by excessive secretion of cortisol, a stress hormone.

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Addison's Disease

A condition characterized by insufficient production of aldosterone, a mineralocorticoid hormone.

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Diabetes Mellitus

A group of metabolic disorders characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both.

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Glucagon

Hormone produced by the alpha cells of the pancreas that elevates blood glucose levels by stimulating glycogen breakdown in the liver.

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Calcitonin

A hormone produced by the thyroid gland that regulates blood calcium levels by promoting its deposition in bones.

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Parathyroid Hormone (PTH)

Hormone secreted by the parathyroid glands that increases blood calcium levels by promoting bone resorption and calcium reabsorption in the kidneys.

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Growth Hormone (GH)

A hormone produced by the anterior pituitary gland, primarily targeting all cells, with bone and skeletal muscles being most affected. It directs actions on fat and carbohydrate metabolism and indirectly stimulates nutrient uptake, collagen formation, and bone deposition through insulin-like growth factors produced by the liver and skeletal muscle.

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Cortisol (hydrocortisone)

This hormone, produced by the adrenal cortex, plays a crucial role in stress response. It increases glucose synthesis in the liver, promoting gluconeogenesis to supply glucose for the brain.

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Adrenocorticotropic hormone (ACTH)

This hormone is released by the anterior pituitary gland and regulates the production and release of cortisol from the adrenal cortex.

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Oxytocin

This hormone, released by the anterior pituitary gland, stimulates labor (smooth muscle contraction) and milk ejection.

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Adrenal glands

This gland, located atop each kidney, consists of two parts: the adrenal medulla and the adrenal cortex. The adrenal cortex produces corticosteroids, while the adrenal medulla produces adrenaline and noradrenaline.

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Thyroid gland

This gland is responsible for producing thyroid hormone, which regulates metabolism, heat production, growth, and blood pressure. It also plays a crucial role in embryonic development.

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Growth Hormone Disorders

These are a group of disorders affecting growth due to imbalances in growth hormone production. These include gigantism, acromegaly, and pituitary dwarfism.

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Hypothyroidism

A condition characterized by an underactive thyroid gland, leading to low metabolic rate, cold sensitivity, poor appetite, and sluggishness in adults. In infants, it manifests as stunted growth, abnormal bone formation, mental retardation, and sluggishness.

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Thyroid Gland Hormones

This gland lies in the upper chest, and its main hormones are T3 and T4. It plays a crucial role in regulating metabolism, growth, and development.

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Study Notes

Multiple Choice Questions

  • Hormone Involved in Diabetes: Insulin

  • Causes of Type 1 Diabetes: Pancreatic cells damaged/autoimmune disease.

  • Signs and Symptoms of Diabetes: Polyuria, Polydipsia, Polyphagia, Nausea, fatigue.

  • Treatment for Diabetes: Monitor blood glucose; insulin injection.

  • Type of Diabetes: Type 2 (hypersecretion) and Gestational diabetes mellitus also Diabetes insipidus - Type 1 (Hyposecretion)

  • Definition of Type 1 Diabetes: Downgrowth of hypothalamic neural tissue, Neural connection to hypothalamus via (hypothalmic-hypophyseal tract), Nuclei of hypothalamus synthesize neurohormones (Oxytocin and ADH), Neurohormones transported and stored in posterior pituitary, Posterior Lobe of the Pituitary Gland, Thyroid Gland, Cerebellum, Thalamus

  • Definition of Adrenal Gland Condition: autoimmune disorder, deficient aldosterone, weight loss, severe dehydration, hypotension (poor cardiac output), muscles weak, crushing syndrome, Addison's disease, Diabetes mellitus, Hyperthyroidism

  • Function of LH in females: LH helps mature follicles of eggs, triggers ovulation and release of estrogen and progesterone.

  • Function of LH in males: LH stimulates production of testosterone

  • Function of Thyroid Gland Hormones:

  • Function of Growth Hormone Disorders:

  • Function of Gonadal Hormone production:

  • Function of Anterior Pituitary Hormone:

  • Major target of Insulin: Liver

  • Function of Insulin: Causes increase blood glucose levels, Regulation: Humoral stimuli (homeostatic balance of blood glucose levels)

  • Definition of Regulation : Regulates electrolytes (Na and K), H2O Follows Na+, Aldosterone most potent mineralocorticoid, Stimulates sodium ion reabsorption and water retention by kidneys; elimination of potassium ions, + Conserve Na, Excrete K+, Release triggered by:

    • Decreasing blood volume and blood pressure
    • Rising blood levels of potassium ion
    • Regulation: Humoral Stimuli (homeostatic balance of blood volume, BP, and levels of K+)
  • Definition of Gonadocorticoids - Adrenal Cortex - Mineralocorticoids Anti-Diuretic hormone, Oxytocin, Hormones of the Posterior Pituitary Gland, Vitamins in the Endocrine System, Neurotransmitters of the Central Nervous System, Enzymes of the Digestive System

  • Adrenal Gland Condition (Definition): Tumor in pituitary, adrenal gland; too much medication, High glucose blood levels, loss in muscle and protein, salt/water retention. "buffalo hump" is redistributed to fat to posterior neck, Crushing syndrome, Acromegaly, Addison's disease

  • Definition of Thyroid gland: 2 distinct portions (lobes), Anterior pituitary (adenohypophysis), Grandular tissue, Posterior pituitary (neurohypophysis), Neural tissue

  • Definition of GH (Somatotropin): Source: Anterior Pituitary, Target: (primary) All cell, Bone and skeletal muscles most affected, Function: Directs action- on fat and carbohydrates metabolism, Indirect action- liver, skeletal muscle , Makes insulin-like growth factors = stimulating nutrient uptake, formation of collagen, bone deposit, Regulation: Hormonal stimuli GHRH, GHIH (somatostatin) from hypothalamus, Hormones of the Anterior Pituitary Gland (GH)

  • Definition of Most Significant Function of GH in Humans: Released in response to ACTH, Patterns of eating and activity, and stress, Target: Liver, Fat, Muscle, Functions: Increases glucose synthesis (liver), Gluconeogenesis promotes glucose, fatty acids, and AA, helps with stress ("glucose for the brain") Regulation: Hormonal stimuli ACTH from Ant Pit

  • Definition of Hormones target: Uterus and breast, Functions: Stimulates labor (smooth muscle contraction) and milk ejection, Regulation: Neural stimuli triggered by sensory information of baby/suckling or stretch receptors in uterine walls/cervix, Oxytocin, Glucagon, Calcitonin, Insulin

  • Definition of Kidney Hormone Function: Reduces water loss (inhibits urination); essential for water balance in body, Causes smooth muscle contraction (increases BP), Regulation: Neural stimuli based on info from osmoreceptors, Anterior Lobe of Pituitary Gland, Anti-diuretic hormone (ADH), Adrenocorticotropic hormone (ACTH), Two organs: Adrenal medulla, Adrenal cortex, T4 (Thyroxine)

  • Functions for Thyroid Hormone: Increases metabolism by increasing the rate of burning carbohydrates (Hyperthyroidism), Increases heat production (body temp), Increases growth (skeletal and nervous system), stimulates development (fetus), Maintains BP, Regulation: Hormonal stimuli, Pancreatic Islets, Gonadal Hormone Production, TH Function

  • Thyroid Hormone (Definition): Two lateral lobes connected by the isthmus, On trachea, inferior to larynx, Follicular cells produce thyroglobulin, Colloid Filled Follicles- add iodine to thyroglobulin, Thyroid hormone precursor, Parafollicular cells produce Calcitonin (↓ blood calcium levels)

  • Gigantism and Acromegaly: Gigantism - Hyper-secretion of GH in children, Acromegaly - Hyper-secretion of GH in adults, Pituitary dwarfism - hypo-secretion of GH in children, Osteoporosis, Epilepsy, Growth Hormone Disorders

  • Addison Disease Symptoms: Thyroid Gland Hormones, Produced by parafollicular cells of the Thyroid Gland, Target: Bone, kidney, Functions: Lowers Blood Ca by increasing bone uptake, increases kidney excretion of Ca Regulation: Humoral stimulation (homeostatic balance Ca), Calcitonin, Oxytocin, Pancreas- Addison's disease

  • Disorders of the Thyroid Gland: Myxedema (adults): low metabolic rate, cold sensitivity, poor appetite, sluggishness, Cretinism (infants): Stunted growth, abnormal bone formation, mental retardation, sluggishness, Diabetes Mellitus, Insulin, Hypoglycemia, Hypothyroidism

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