Diabetes and Glycogen Storage Diseases Quiz

Which glucose transporter type is primarily responsible for glucose uptake in the liver?

What symptom is NOT typically associated with diabetes mellitus?

Which type of glycogen storage disease is characterized by muscle symptoms during strenuous exercise?

Which of the following is a characteristic of Type 1 Diabetes Mellitus?

What laboratory finding indicates excess glucose in the urine?

Which sugar substitute is made from amino acids and is unsuitable for individuals with phenylketonuria?

Which condition results from carbohydrate deficiency and is characterized by weight loss and muscle wasting?

Which of the following is a potential consequence of hyperglycemia?

Glucose Transporters

Facilitate glucose movement across cell membranes.

Glycogen Storage Diseases (GSD)

Inherited conditions affecting glycogen storage and utilization.
Liver Forms (Type I, III, IV, VI): Cause hepatomegaly (enlarged liver) and hypoglycemia (low blood sugar).
Muscle Forms (Type II, IIIA, V, VII): Symptoms appear during strenuous exercise.

Carbohydrate Deficiencies

Marasmus: Caused by a shortage of carbohydrates.
Diabetes Mellitus: A metabolic disease due to insufficient insulin production.

Diabetes Mellitus

Type 1 (IDDM): Common in adolescents; results from the autoimmune destruction of insulin-producing cells in the pancreas.
Type 2 (NIDDM): Often develops later in life; associated with obesity and genetic predisposition.

Symptoms of Diabetes Mellitus

4P's:
- Polydipsia: Excessive thirst.
- Polyuria: Excessive urination.
- Polyphagia: Excessive hunger.
- Persistence of Non-Healing Wounds: Slow wound healing.

Common Laboratory Findings in Diabetes

Glycosuria: Elevated glucose levels in the urine.
Hyperglycemia: High blood glucose levels.

Sugar Substitutes

Aspartame: An amino acid-based sweetener; not suitable for those with phenylketonuria (PKU).
Saccharin: An artificial sweetener; can induce insulin release.
Erythritol: A natural sugar alcohol; low-calorie and does not promote tooth decay.
Xylitol: Found in fruits; considered safe for individuals with diabetes.

Test your understanding of glucose transporters, glycogen storage diseases, and carbohydrate deficiencies. This quiz covers diabetes mellitus types, symptoms, and related metabolic conditions. Engage with key concepts that are essential for understanding these conditions.