Developmental Biology Overview

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Questions and Answers

What primarily determines the fate of a cell in mosaic development?

  • Genetic programming of the cell
  • Cytoplasmic determinants distributed unequally (correct)
  • Cell interactions with neighboring cells
  • Environmental factors affecting the tissue

In regulative development, what allows for compensation when a blastomere is excised?

  • All cells are predetermined to form specific structures
  • Neighboring cells can change their differentiation pathways (correct)
  • The excised blastomere cannot develop into any structure
  • The remaining cells can take on specialized functions (correct)

What is a characteristic feature of vertebrates in terms of development?

  • Incorporation of mosaic and regulative development (correct)
  • Limited potential of cells after initial cleavage
  • Permanent cell fate determined at the earliest stage
  • Complete reliance on genetic inheritance for cell fate

How does the potential of cells differ in regulative development as compared to mosaic development?

<p>Cells can develop into any type throughout their early stages in regulative development (D)</p> Signup and view all the answers

What happens to a cell when it is isolated early in cleavage during regulative development?

<p>It can still develop into a complete individual (A)</p> Signup and view all the answers

What is the primary focus of embryology?

<p>The study of embryos (A)</p> Signup and view all the answers

Which term is used to define the development of a new individual from a fertilized oocyte?

<p>Ontogenic development (C)</p> Signup and view all the answers

What does gametogenesis involve?

<p>Generation of specialized cells for fertilization (C)</p> Signup and view all the answers

What are cytoplasmic determinants responsible for in mosaic development?

<p>Influencing the fate of daughter cells during division (D)</p> Signup and view all the answers

What is a consequence of excising one cell from a developing embryo in a mosaic mode of development?

<p>It will likely result in a defective larva (C)</p> Signup and view all the answers

What is meant by 'morphogenesis' in the context of ontogenic development?

<p>The organization of cells into structured forms (A)</p> Signup and view all the answers

In which type of species is mosaic development commonly observed?

<p>Molluscs (C)</p> Signup and view all the answers

Which process contributes to cellular diversity during ontogenic development?

<p>Cell differentiation from stem cells (B)</p> Signup and view all the answers

Flashcards

Embryology

The study of embryos.

Embryo

An early stage of development where the animal doesn't resemble the adult form.

Developmental Biology

The analysis of how an organism develops.

Gametogenesis

The process of creating specialized cells involved in fertilization (gametes).

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Oogenesis

The process of generating and maturing female gametes (oocytes).

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Spermatogenesis

The process of generating and maturing male gametes (spermatozoa).

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Mosaic Development

Development where cell fate is determined by cytoplasmic determinants.

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Cytoplasmic determinants

Substances unequally distributed in a cell, affecting cell development.

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Regulative Development

A developmental pattern where a cell's fate is determined by interactions with its neighboring cells, not by pre-existing cytoplasmic determinants.

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Totipotential

The ability of a cell to develop into any cell type in the body, including those that form the placenta.

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Cell-Cell Interaction

The communication and influence between neighboring cells that can affect their developmental pathways.

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How Regulative Development works

If a blastomere is removed early in cell division, the remaining cells can compensate and still form a complete, normal embryo.

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Study Notes

Developmental Biology and Embryology

  • Developmental biology is the study of biological development, evolving from embryology, the study of embryos.
  • An embryo is an early stage of development where the animal doesn't yet resemble the adult form.
  • Development is a series of correlated events.
  • Ontogeny refers to the development of an individual from a fertilized oocyte (sexual reproduction) or from a parent organism (asexual reproduction).
  • Phylogeny refers to the evolutionary development of a species, progressing from simple to complex life forms.

Gametogenesis

  • Development typically starts with gametogenesis, the generation of gametes (specialized cells involved in fertilization).
  • Oogenesis is the generation and maturation of oocytes.
  • Spermatogenesis is the generation and maturation of spermatozoa.

Major Achievements of Ontogenetic Development

  • Growth: Generation of cell numbers.
  • Differentiation: Cellular diversity within a generation (e.g., from embryonic stem cells to various cell types).
  • Morphogenesis: Cellular order within a generation, creating the organism's body form specific to the species.
  • Continuity: Maintenance of life.

Types of Development

Mosaic Development

  • Cell fate is determined by cytoplasmic determinants unequally distributed to daughter cells during division.
  • In mosaic development, the fate of a cell is limited, and early removal of a cell prevents normal development. Example: Mollusks in vertebrates.Cells gain specific cytoplasmic determinants to gain a particular path (e.g., muscle or organ).Removing one cell can't be replaced.

Regulatory Development

  • Cell fate depends on interactions with neighboring cells (cell-to-cell signaling).
  • Regulatory development is characterized by totipotency (cells can become any cell type) and compensation.
  • Removal of a blastomere early in cleavage can allow development of a complete new organism.
  • Example: Vertebrates (but often combined with mosaic development) . If a blastomere is removed, the remaining cells adapt and form a normal embryo.

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