Podcast
Questions and Answers
What is the process where only certain genes are accessible for activation and transcription due to modifications of chromatin in developing gametes?
What is the process where only certain genes are accessible for activation and transcription due to modifications of chromatin in developing gametes?
- Genetic recombination
- Crossing over
- Gene duplication
- Genomic imprinting (correct)
Which type of methylation alters CpG dinucleotides by DNA methyltransferases during germ line differentiation?
Which type of methylation alters CpG dinucleotides by DNA methyltransferases during germ line differentiation?
- Protein methylation
- RNA methylation
- CpG methylation (correct)
- Histone methylation
What allows reactivation of imprinted genes by erasing most CpG methylations in primordial germ-line cells during embryonic development?
What allows reactivation of imprinted genes by erasing most CpG methylations in primordial germ-line cells during embryonic development?
- DNA replication
- Histone modification
- CpG demethylation (correct)
- RNA splicing
In which stage of embryo development do eggs and sperm end up with different, distinct imprints?
In which stage of embryo development do eggs and sperm end up with different, distinct imprints?
Why do relatively few genes, about 200 in humans and mice, undergo imprinting?
Why do relatively few genes, about 200 in humans and mice, undergo imprinting?
What process is responsible for dosage compensation in human females to avoid a double dose of X gene products?
What process is responsible for dosage compensation in human females to avoid a double dose of X gene products?
What is the term for the process where one of the two X chromosomes in every cell of an early embryo is inactivated?
What is the term for the process where one of the two X chromosomes in every cell of an early embryo is inactivated?
"Crossing over" occurs between homologous chromosomes during which phase of cell division?
"Crossing over" occurs between homologous chromosomes during which phase of cell division?
"RNA splicing" is a post-transcriptional modification that involves the removal of:
"RNA splicing" is a post-transcriptional modification that involves the removal of:
During which stage of embryonic development does a second wave of de-methylation occur in mouse embryos?
During which stage of embryonic development does a second wave of de-methylation occur in mouse embryos?
