Developmental Biology: Gametogenesis and PGCs
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Gametogenesis is the process of formation and development of highly specialized sex cells called gametes or ______ cells

germs

Elsewhere in the body of the embryo, undifferentiated primordial germ cells (PGCs) migrate into the gonads where they begin to differentiate depending on the sex of the organism: spermatogonia for males, ______ for females

oogonia

Four processes occur during gametogenesis: mitosis, growth, ______, and differentiation

meiosis

Meiotic divisions reduce the chromosome number in half and allow for ______

<p>variation</p> Signup and view all the answers

Gametogenic cells undergo mitotic divisions to increase their ______

<p>number</p> Signup and view all the answers

Differentiation makes the germ cells specialized to carry out their specific ______

<p>functions</p> Signup and view all the answers

Spermatogenesis refers to the entire sequence of events by which the primitive germ cells, the diploid spermatogonia, give rise to haploid spermatozoa or ______ cells.

<p>sperm</p> Signup and view all the answers

This process occurs in the seminiferous tubules inside the ______.

<p>testis</p> Signup and view all the answers

Each tubule is lined with a germinal epithelium that is made up of two types of cells: the developing spermatogenic cells in various stages of development, and the Sertoli (sustentacular) cells that support the development of the ______ cells.

<p>spermatogenic</p> Signup and view all the answers

Leydig cells located outside of the Seminiferous tubules are responsible for secreting the hormone testosterone for ______.

<p>spermatogenesis</p> Signup and view all the answers

Once the migrating primordial germ cells (PGCs) have reached the developing gonad (future testis), they differentiate into the first type of spermatogenic cells, the ______.

<p>spermatogonia</p> Signup and view all the answers

The spermatogonia remain dormant until conditions are favorable for ______.

<p>spermatogenesis</p> Signup and view all the answers

In humans, spermatogenesis begins at ______.

<p>puberty</p> Signup and view all the answers

The diploid spermatogonia that differentiated from the PGCs are located close to the basement membrane of the seminiferous tubule. These cells undergo mitotic divisions and give rise to two types of ______.

<p>spermatogonia</p> Signup and view all the answers

Spermatogonium A remains close to the basement membrane of the seminiferous tubule. It retains its mitotic function, thus responsible for the continuous supply of ______ cells throughout the life of the organism.

<p>spermatogenic</p> Signup and view all the answers

Spermatogonium B is displaced farther from the basement membrane of the seminiferous tubule towards the lumen. It does not retain its mitotic function but enters the next phase of ______.

<p>spermatogenesis</p> Signup and view all the answers

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