15 Questions
What is the primary use of Desonide in dermatology?
To reduce swelling and redness
How does Desonide suppress inflammation?
By inhibiting cytokine release
In a clinical trial evaluating vasoconstrictive properties, Desonide Gel 0.05% was compared to all of the following EXCEPT:
Triamcinolone acetonide cream 0.1%
What is the main mechanism of action of Desonide in reducing redness?
Reducing vasodilation
Which of the following is NOT a formulation in which Desonide is available?
Oral tablets
How does Desonide modulate the immune response in the skin?
By suppressing leukocyte migration
What was the objective of the clinical trial-3?
To observe and analyze the clinical efficacy of mucopolysaccharide polysulfate (MPS) ointment combined with desonide ointment in treatment of infantile eczema
What was the outcome of the clinical trial-4?
Significant improvements in IGA scores at day 3 and day 7
What is the purpose of comparing Desonide with other topical corticosteroids or non-steroidal alternatives in some trials?
To assess its relative efficacy and safety
What was the study design for Clinical trial-2?
Multicenter open-label study in pediatric subjects with moderate to severe Atopic Dermatitis
What was the gender distribution in the study designed to compare the vasoconstriction effect of Desonide formulation?
(6M; 30F; 27 Caucasian; 3 Hispanic; 6 Asian)
What was observed in the study designed to compare the vasoconstriction effect of Desonide formulation?
Vasoconstriction potency ranking for Desonide Gel 0.05% equivalent to that of DesOwenCI Lotion 0.05%
What was the main focus of Clinical trial-2?
(evaluating the safety and systemic tolerance of Desonide Gel 0.05%)
What is being compared in Clinical trial-3?
(mucopolysaccharide polysulfate ointment combined with desonide ointment)
What was observed in Clinical trial-2 after four weeks of twice-daily applications?
(100% subjects showed normal adrenal response)
Test your knowledge about the topical corticosteroid Desonide and its use in dermatology. Learn about its potency, formulations, mechanisms of action, and effects on skin cells.
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