Dermatology Quiz: Hyperpigmentation and Melasma
42 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which treatment is NOT typically used for post-inflammatory hyperpigmentation?

  • Microdermabrasion
  • Cryotherapy (correct)
  • Chemical peels with salicylic acid
  • Topical retinoids
  • What is a primary characteristic of post-inflammatory hyperpigmentation (PIH)?

  • It always presents with severe inflammation.
  • It follows an injury or inflammatory disorder. (correct)
  • It is most common in individuals with fair skin types (Fitz 1-2).
  • It appears as hypopigmented macules and papules.
  • Which skin type is most likely to be affected by post-inflammatory hyperpigmentation?

  • Fitzpatrick skin type III
  • Fitzpatrick skin type IV (correct)
  • Fitzpatrick skin type I
  • Fitzpatrick skin type II
  • Which of the following best describes the typical appearance of melasma?

    <p>Bilateral, asymptomatic, brown patches, common on the face. (A)</p> Signup and view all the answers

    Which of the following is considered a risk factor for melasma?

    <p>Use of estrogen-containing contraceptives (C)</p> Signup and view all the answers

    What is the typical distribution of centrofacial melasma?

    <p>Forehead, cheeks, nose, upper lip (A)</p> Signup and view all the answers

    What is the typical timeframe for spontaneous resolution of post-inflammatory hyperpigmentation lesions?

    <p>6-12 months (D)</p> Signup and view all the answers

    Which of the following is an effective treatment for melasma?

    <p>Sunscreen (D)</p> Signup and view all the answers

    What is the primary concern regarding melasma treatment, even when successful?

    <p>Reappearance of pigmentation upon sun exposure. (B)</p> Signup and view all the answers

    Which of these is NOT a recommended treatment for melasma?

    <p>Oral antibiotics (C)</p> Signup and view all the answers

    Which best describes the appearance of lichen sclerosus on mucosal surfaces?

    <p>Atrophic, white, and glistening with a wrinkled texture. (A)</p> Signup and view all the answers

    Which area is least likely to be primarily affected by lichen sclerosus?

    <p>The outer areas of the labia majora. (B)</p> Signup and view all the answers

    What is a significant symptom of lichen sclerosus that can result in secondary skin changes?

    <p>Extreme itchiness and soreness (D)</p> Signup and view all the answers

    Which of the following is considered a possible etiological factor in lichen sclerosus, according to the text?

    <p>Irritants. (B)</p> Signup and view all the answers

    What is the significance of ECM-1 antibodies found in women with vulval lichen sclerosus?

    <p>They suggest an autoimmune component to the disease. (C)</p> Signup and view all the answers

    What is the typical ratio of female to male cases in lichen sclerosus?

    <p>10:1 (A)</p> Signup and view all the answers

    What characteristic defines vitiligo?

    <p>Acquired depigmentation due to autoimmune destruction of melanocytes. (D)</p> Signup and view all the answers

    Which topical treatment is likely to cause less stinging when applied for skin conditions?

    <p>Ointment base topical steroid. (A)</p> Signup and view all the answers

    How often should a topical steroid ointment be applied initially for treatment?

    <p>Once a day. (B)</p> Signup and view all the answers

    Which of the following is a systemic option for treating severe skin conditions when topical therapy fails?

    <p>Intralesional corticosteroids. (A)</p> Signup and view all the answers

    What is the expected duration for one 30-g tube of topical steroid to last with regular use?

    <p>3 to 6 months. (A)</p> Signup and view all the answers

    What is a common clinical characteristic of acanthosis nigricans?

    <p>Velvety, hyperpigmented patches on the neck (A)</p> Signup and view all the answers

    Which population shows the highest estimated prevalence of acanthosis nigricans?

    <p>Native Americans (B)</p> Signup and view all the answers

    Which of the following conditions is acanthosis nigricans predominantly linked to?

    <p>Insulin resistance (C)</p> Signup and view all the answers

    What type of growth factor receptors are involved in the pathology of acanthosis nigricans?

    <p>Type 1 insulin-like growth factor receptors (C)</p> Signup and view all the answers

    In rare cases, acanthosis nigricans may be associated with what serious condition?

    <p>Internal malignancy (A)</p> Signup and view all the answers

    What is the percentage of the population affected by vitiligo?

    <p>1% (C)</p> Signup and view all the answers

    Which diagnosis method highlights hypopigmented areas in vitiligo?

    <p>Wood’s lamp (D)</p> Signup and view all the answers

    What is the largest risk factor associated with vitiligo?

    <p>Thyroid disease (D)</p> Signup and view all the answers

    What is a common first-line treatment for vitiligo?

    <p>Calcineurin inhibitors (B)</p> Signup and view all the answers

    How often should whole-body or localized UVB phototherapy be administered for vitiligo?

    <p>3 times per week (B)</p> Signup and view all the answers

    What percentage of people with vitiligo may show a positive family history?

    <p>30% (B)</p> Signup and view all the answers

    What is the primary concern regarding the prognosis of vitiligo?

    <p>It is associated with an increased risk for skin cancer (B)</p> Signup and view all the answers

    Which systemic therapy may be used for quick stabilization of active vitiligo disease?

    <p>Short pulse systemic steroids (A)</p> Signup and view all the answers

    What is a common symptom of lichen sclerosus?

    <p>Dysuria or anuria (A)</p> Signup and view all the answers

    What age group is most often diagnosed with lichen sclerosus?

    <p>Women over 50 (D)</p> Signup and view all the answers

    What complication is associated with untreated lichen sclerosus?

    <p>Increased risk of squamous cell carcinoma (D)</p> Signup and view all the answers

    Which of the following is a recommended hygiene measure for managing genital lichen sclerosus?

    <p>Wash with non-soap cleanser once or twice daily (D)</p> Signup and view all the answers

    Which of the following might NOT be associated with a personal history affecting lichen sclerosus?

    <p>Chronic allergies (A)</p> Signup and view all the answers

    What characteristic describes the appearance of lesions associated with invasive squamous cell carcinoma in lichen sclerosus?

    <p>Enlarging lump or sore that fails to heal (D)</p> Signup and view all the answers

    What physical change can occur in the external genitalia due to lichen sclerosus?

    <p>Burial of the clitoris (A)</p> Signup and view all the answers

    Which statement is TRUE regarding the relationship between lichen sclerosus and other autoimmune diseases?

    <p>Family history of autoimmune diseases may increase risk (B)</p> Signup and view all the answers

    Flashcards

    Acanthosis Nigricans

    Velvety, thickened dark patches on skin, often in folds.

    Etiology of Acanthosis Nigricans

    Often linked to insulin resistance, obesity, and diabetes.

    Prevalence of Acanthosis Nigricans

    Common in 13.3% of African Americans and 5.5% of Latinos.

    Clinical Presentation

    Characterized by darkening and hyperkeratosis of skin.

    Signup and view all the flashcards

    Malignant Acanthosis Nigricans

    Rapid lesion development in non-obese middle-aged individuals; rare.

    Signup and view all the flashcards

    Post-Inflammatory Hyperpigmentation (PIH)

    Temporary skin pigmentation following injury or inflammation, commonly seen in darker skin types.

    Signup and view all the flashcards

    Diagnosis of PIH

    Usually clinical based on history and skin type; biopsy may be necessary.

    Signup and view all the flashcards

    Treatment for PIH

    Identify inflammation source, recommend sunscreen; can use skin lighteners and retinoids.

    Signup and view all the flashcards

    Melasma

    Hyperpigmented patches on the face or sun-exposed skin, asymptomatic with irregular borders.

    Signup and view all the flashcards

    Common patterns of Melasma

    Centrofacial (forehead, cheeks, nose), Malar (cheeks and nose), Mandibular (jawline).

    Signup and view all the flashcards

    Risk factors for Melasma

    Pregnancy, estrogen in contraceptives, hormonal therapy, and sun exposure increase chances of melasma.

    Signup and view all the flashcards

    Pigmentation resolution in PIH

    Lesions typically resolve spontaneously within 6-12 months but can be aided by treatments.

    Signup and view all the flashcards

    Onset Age for Melasma

    Melasma typically arises between ages 20-40, more common in women.

    Signup and view all the flashcards

    Emollients

    Substances applied to skin to relieve dryness and itching, acting as a barrier.

    Signup and view all the flashcards

    Topical Steroids

    Medications applied to the skin to reduce inflammation and symptoms of skin conditions.

    Signup and view all the flashcards

    Clobetasol Propionate

    A high potency topical steroid often used in treating severe skin conditions.

    Signup and view all the flashcards

    Vitiligo

    A skin condition characterized by depigmented macules and patches due to autoimmune destruction of melanocytes.

    Signup and view all the flashcards

    Intralesional Corticosteroids

    Corticosteroids injected directly into lesions to treat severe skin conditions.

    Signup and view all the flashcards

    Dysuria

    Painful or difficult urination often linked to urinary tract issues.

    Signup and view all the flashcards

    Anuria

    A condition where the body produces no urine.

    Signup and view all the flashcards

    Lichen Sclerosus

    A skin condition that affects the genital area, causing itching and pain.

    Signup and view all the flashcards

    Cancer Risk in Lichen Sclerosus

    Increased risk of squamous cell carcinoma in patients with untreated lichen sclerosus.

    Signup and view all the flashcards

    Symptoms of Lichen Sclerosus

    Includes itching, pain, and potentially fissures in the genital area.

    Signup and view all the flashcards

    Biopsy in Lichen Sclerosus

    A procedure to confirm diagnosis, especially for unhealing lesions.

    Signup and view all the flashcards

    Treatment Measures

    Gentle washing and using non-soap cleansers for managing lichen sclerosus.

    Signup and view all the flashcards

    Family History and Lichen Sclerosus

    Higher likelihood of lichen sclerosus in individuals with a family history of autoimmune diseases.

    Signup and view all the flashcards

    Prevalence of Vitiligo

    Affects about 1% of the population, often beginning before age 20.

    Signup and view all the flashcards

    Etiology of Vitiligo

    Association with stress, illness, or skin trauma; can also relate to thyroid disease.

    Signup and view all the flashcards

    Diagnosis of Vitiligo

    Utilizes Wood’s lamp and skin biopsy to detect absence of melanocytes.

    Signup and view all the flashcards

    Prognosis of Vitiligo

    Condition progresses slowly; risk of sunburns and skin cancer increases.

    Signup and view all the flashcards

    First-line Treatment

    Includes topical corticosteroids and calcineurin inhibitors for management.

    Signup and view all the flashcards

    Second-line Treatment

    Involves Ruxolitinib cream and phototherapy for more severe cases.

    Signup and view all the flashcards

    Older Systemic Therapy

    Includes short pulse therapy with systemic steroids to slow disease progression.

    Signup and view all the flashcards

    Melasma Treatment

    Methods to treat melasma include minimizing sun exposure and using broad-spectrum sunscreens.

    Signup and view all the flashcards

    Oral Anti-Oxidants

    Supplements like omega-3, omega-6, and Vitamin E support skin health in melasma treatment.

    Signup and view all the flashcards

    Topical Treatments for Melasma

    Topical agents like kojic acid, ascorbic acid, and hydroquinone are used to lighten pigmentation.

    Signup and view all the flashcards

    Lichen Sclerosis Symptoms

    Itchy and sore skin with atrophic white papules in lichen sclerosis.

    Signup and view all the flashcards

    Lichen Sclerosis Etiology

    Causes may involve genetic, hormonal, traumatic, and infectious factors leading to autoimmune responses.

    Signup and view all the flashcards

    Female to Male Ratio in Lichen Sclerosis

    The ratio is approximately 10:1, indicating a higher prevalence in females.

    Signup and view all the flashcards

    Characteristics of Lichen Sclerosis

    Features include ivory white papules with a smooth, atrophic surface on genital areas.

    Signup and view all the flashcards

    Vulvar Lichen Sclerosis

    Primarily affects the non-hair bearing areas of the vulva and can extend to other regions.

    Signup and view all the flashcards

    More Like This

    Anti-Inflammatory Drugs Ch. 8 Flashcards
    20 questions
    Acanthosis Nigricans and PIH Overview
    44 questions
    Use Quizgecko on...
    Browser
    Browser