Depressive Disorders according to DSM-5

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What is the primary neurobiological mechanism underlying depressive disorders, according to the biological etiological theory?

Dysregulation of the hypothalamic-pituitary-adrenal axis

A patient presents with a history of childhood trauma and experiences feelings of worthlessness and hopelessness. Which cognitive theory best explains the development of depressive symptoms in this individual?

Schemas theory

A 35-year-old woman is diagnosed with major depressive disorder. According to the DSM-5 criteria, what is the minimum duration of symptoms required for this diagnosis?

2 weeks

A patient with depressive symptoms is diagnosed with a comorbid anxiety disorder. Which of the following is a key consideration in the differential diagnosis of depressive disorders?

<p>Ruling out medical conditions that mimic depressive symptoms</p> Signup and view all the answers

A nurse is developing a care plan for a patient with depression. Which of the following nursing diagnoses is most relevant to this patient's symptoms?

<p>Powerlessness</p> Signup and view all the answers

What is the primary characteristic that distinguishes melancholic features from atypical features in major depressive disorder?

<p>Loss of interest in activities and a lack of reactivity to stimuli</p> Signup and view all the answers

A patient with major depressive disorder experiences a significant improvement in symptoms after 6 weeks of treatment. What is the most likely course of this patient's illness?

<p>The patient will likely experience a full remission of symptoms</p> Signup and view all the answers

What is the most common comorbid disorder associated with major depressive disorder?

<p>Anxiety disorder</p> Signup and view all the answers

A patient with major depressive disorder experiences a significant worsening of symptoms after a stressful life event. What is the most likely factor contributing to this worsening?

<p>Environmental factors</p> Signup and view all the answers

What is the primary factor that influences the course and prognosis of major depressive disorder?

<p>Severity of symptoms</p> Signup and view all the answers

Study Notes

Depressive Disorders: Introduction

  • Depressive disorders are a group of mental health conditions characterized by feelings of sadness, hopelessness, and a loss of interest in activities
  • They are one of the most common mental health disorders, affecting millions of people worldwide

Etiology

Biological Theory

  • Genetic factors: individuals with a family history of depression are more likely to develop the disorder
  • Neurotransmitter imbalance: decreased levels of serotonin, dopamine, and norepinephrine contribute to depressive symptoms
  • Hormonal changes: thyroid disorders, Cushing's syndrome, and hormonal fluctuations during pregnancy or menopause can contribute to depression

Psychodynamic Theory

  • Unresolved unconscious conflicts and childhood experiences can contribute to depressive symptoms
  • Defense mechanisms, such as repression and denial, can prevent individuals from coping with negative emotions

Cognitive Theory

  • Negative thought patterns and cognitive distortions contribute to depressive symptoms
  • Individuals with depression may have a negative self-image, distorted thinking, and a pessimistic outlook

Learned Helplessness

  • Repeated exposure to uncontrollable and inescapable stressors can lead to feelings of hopelessness and powerlessness
  • Individuals may develop a perception that they are unable to change their circumstances, leading to depressive symptoms

Stressful Life Events

  • Significant life changes, such as the loss of a loved one, divorce, or job loss, can trigger depressive symptoms
  • Traumatic events, such as abuse or neglect, can increase the risk of developing depression

Epidemiology

  • Depression is a leading cause of disability worldwide, affecting approximately 322 million people
  • Women are more likely to experience depression than men, with a lifetime prevalence of 1 in 5
  • Depression can occur at any age, but the highest prevalence is among adults aged 25-44

Clinical Features

  • Depressed mood: feelings of sadness, hopelessness, and emptiness
  • Anhedonia: loss of interest in activities that were once enjoyable
  • Appetite and sleep disturbances: changes in appetite and sleep patterns
  • Fatigue: feeling tired or lacking energy
  • Concentration difficulties: difficulty concentrating or making decisions

DSM-5 Criteria

  • Five or more symptoms must be present for at least 2 weeks, with at least one of the symptoms being depressed mood or anhedonia
  • Symptoms must cause significant distress or impairment in social, occupational, or other areas of functioning

Course and Prognosis

  • Depression can be a recurrent disorder, with many individuals experiencing multiple episodes
  • Early treatment can improve outcomes and reduce the risk of recurrence

Differential Diagnosis

  • Dysthymia: a chronic, low-grade depressive disorder
  • Bipolar disorder: a mood disorder characterized by alternating periods of mania and depression
  • Anxiety disorders: disorders characterized by excessive worry, fear, or anxiety
  • Substance use disorders: disorders characterized by the misuse of substances

Nursing Diagnosis

  • Risk for suicide: individuals with depression are at an increased risk for suicide
  • Impaired social interaction: depression can impair social relationships and daily functioning
  • Disturbed sleep pattern: changes in sleep patterns can contribute to depressive symptoms

Treatment

  • Pharmacological interventions: medications, such as antidepressants, can help manage depressive symptoms
  • Psychotherapy: cognitive-behavioral therapy, psychodynamic therapy, and interpersonal therapy can help individuals cope with depression
  • Lifestyle modifications: regular exercise, healthy diet, and stress management can help reduce symptoms of depression

Depressive Disorders according to DSM-5

Introduction

  • Depressive disorders are a group of mental health conditions characterized by feelings of sadness, hopelessness, and loss of interest in activities
  • Can affect anyone, regardless of age, gender, or background

Etiology

  • Biological Theory: imbalance of neurotransmitters such as serotonin, dopamine, and norepinephrine
  • Psychodynamic Theory: unconscious conflicts and feelings of guilt, anger, and low self-esteem
  • Cognitive Theory: negative thought patterns and cognitive distortions
  • Learned Helplessness: feeling of powerlessness due to past experiences
  • Stressful Life Events: loss of a loved one, job change, or financial problems

Epidemiology

  • Depressive disorders are common, affecting approximately 1 in 10 people
  • Women are more likely to experience depression than men
  • Depression can occur at any age, but most common in young adults

Clinical Features

  • Persistently feeling sad, empty, or hopeless
  • Loss of interest in activities, including those that were once enjoyable
  • Changes in appetite, sleep patterns, or energy levels
  • Difficulty concentrating, making decisions, or remembering things
  • Feeling guilty, worthless, or suicidal

DSM-5 Criteria

  • At least 5 symptoms of depression present nearly every day for 2 weeks
  • Symptoms must be severe enough to cause significant distress or impairment
  • Symptoms must not be due to a medical condition, substance abuse, or bereavement

Course and Prognosis

  • Major depressive disorder (MDD) can be a chronic condition, with recurring episodes
  • Episodes can last from weeks to months, or even years
  • Recovery is possible, but relapse is common
  • Treatment can improve symptoms and reduce the risk of relapse

Differential Diagnosis

  • Distinguishing depression from other mental health conditions, such as anxiety, bipolar disorder, or dysthymia
  • Ruling out other medical conditions that may cause similar symptoms

Nursing Diagnosis

  • Identifying specific problems and needs of the individual with depression
  • Developing a plan to address these problems and promote recovery

Treatment

  • Medications, such as antidepressants, to help manage symptoms
  • Psychotherapy, such as cognitive-behavioral therapy (CBT), to address underlying issues
  • Lifestyle changes, such as regular exercise, healthy diet, and social support
  • Combination of these approaches often most effective

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