Podcast
Questions and Answers
Match the following antidepressants with their corresponding effects:
Match the following antidepressants with their corresponding effects:
Duloxetine = Treats chronic neuropathic pain Venlafaxine = Targets serotonin and norepinephrine reuptake Desvenlafaxine = Active metabolite of Venlafaxine Selegiline = Transdermal patch for patients unresponsive to SSRIs and TCAs
Match the following pain management drugs with their properties:
Match the following pain management drugs with their properties:
Morphine = Pure agonist targeting Mu receptors Naloxone = Used to reverse overdose; pure antagonist Buprenorphine = Partial mu agonist with limited respiratory depression Fentanyl = Mu antagonist
Match the following sleep-related substances with their mechanisms:
Match the following sleep-related substances with their mechanisms:
Ramelton = Melatonin agonist Suvorexant = Orexin receptor antagonist Caffeine = Adenosine receptor antagonist Barbiturates = Suppress REM sleep
Match the following psychedelics with their characteristics:
Match the following psychedelics with their characteristics:
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Match the following substances with their uses in addiction treatment:
Match the following substances with their uses in addiction treatment:
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Match the following opioid substances with their characteristics:
Match the following opioid substances with their characteristics:
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Match the following substances related to cannabis with their functions:
Match the following substances related to cannabis with their functions:
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Match the following medications used in alcohol withdrawal treatment:
Match the following medications used in alcohol withdrawal treatment:
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Study Notes
Depression Treatments
- Duloxetine treats chronic neuropathic pain. Its active metabolite is desvenlafaxine.
- Selegiline, a transdermal patch, is effective in patients unresponsive to SSRIs and TCAs.
- Venlafaxine targets serotonin and norepinephrine reuptake.
Pain and Opioids
- Morphine targets Mu receptors and is a pure agonist.
- Naloxone reverses opioid overdose; a pure antagonist.
- Buprenorphine limits respiratory depression and abuse potential, acting as a partial Mu agonist.
- Suboxone combines Buprenorphine and Naloxone.
- Pentazocine is an analgesic with dysphoric effects; a weak Mu antagonist and Kappa agonist.
- Fentanyl is a Mu antagonist.
- Tramadol is a mixed agonist.
- Laudanum is a mixture of alcohol and opioids.
Pain Management (Non-Opioid)
- Aspirin and other NSAIDs decrease inflammation.
- Gabapentin and Pregabalin decrease nociceptor excitation.
- Opioids decrease neurotransmitter release by nociceptors.
- Antidepressants and opioids activate anti-pain pathways.
- Opioids influence cognitive and emotional processing.
Sleep Medications
- Ramelteon is a melatonin agonist.
- Suvorexant is an orexin receptor antagonist.
- Caffeine is an adenosine receptor antagonist.
- Barbiturates and alcohol suppress REM sleep.
- Z-drugs (Zaleplon, Zolpidem, Eszopiclone) are short- to mid-acting sleep aids.
Psychedelics
- Scopolamine is an anticholinergic used for sedation and twilight anesthesia.
- Psilocybin, found in mushrooms, is chemically similar to serotonin.
- MDMA enhances communication and empathy.
- LSD causes visual, auditory, and space/time distortions.
- Mescaline is chemically similar to dopamine and norepinephrine.
Cannabis Treatment
- Rimonabant is a cannabinoid antagonist that suppresses appetite.
- Carboxy THC is used in urine tests to detect THC.
Alcohol Treatment
- Diazepam prevents withdrawal seizures.
- Disulfiram prolongs the unpleasant effects of alcohol to deter relapse.
- Naltrexone prevents relapse.
- Lamotrigine is an anticonvulsant.
Addiction Treatment
- Naloxone is a heroin antagonist.
- Methadone is a heroin agonist.
- Nicotine patches are a cigarette alternative.
- Varenicline (Chantix) is a partial nicotine agonist.
- Disulfiram (Antabuse) is an alcohol aversive treatment.
- Suboxone is an aversive treatment for opioids.
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Description
Explore the various treatments for depression and pain management, focusing on both opioid and non-opioid options. Learn about the mechanisms of drugs like Duloxetine, Morphine, and NSAIDs, and their effectiveness in clinical settings. This quiz provides insight into the crucial aspects of pharmacology related to mental health and pain relief.